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PROSITE entry PS51965


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General information about the entry

Entry name [info] AG_I_II_AR
Accession [info] PS51965
Entry type [info] MATRIX
Date [info] 02-JUN-2021 CREATED;
02-JUN-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51965
Associated ProRule [info] PRU01310

Name and characterization of the entry

Description [info] Streptococcus antigen I/II alanine-rich (Ag I/II A) repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=82;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=82;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.3393261; R2=0.0028050; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=2910; N_SCORE=11.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=1127; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-32; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='Q';  M= 41,-74, 36, 41,-42,-64,-32,-72, 26,-36,-65, -3,-66, 49,-32,-26,-13,-48,-80,-67;
/M: SY='A';  M= 62,-71, 24, 22,-78,-61,-63,-62, 25,-53,-65,-29, 14, 16,-56,-28, -1,-28,-80,-71;
/M: SY='K';  M= 27,-70, 12, -1,-74,-62,-21,-71, 45,-33,-64, 36,-66,  1,-28, 24, 31,-60,-80,-22;
/M: SY='K';  M=-40,-74,-24, 35,-74,-68,-57,-69, 66,-27,-63, 46,-66, 31,-43,-32, 24,-17,-79,-30;
/M: SY='A';  M= 71,-69, -1, 43,-79,-59,-63,-71,-13,-63,-65,-43,-65, 31,-15,-47, 10,-61,-79,-71;
/M: SY='Q';  M= 47,-75, 46,  6,-83,-39,-57,-76, 15,-74,-66,-35,-66, 80,-51,-12,-35,-69,-80,-68;
/M: SY='Y';  M= 20,-78,-72,-70,-23,-49,-15,  7,-66,-33,-51,-70,-79,  4,-65,-62,-63,-30,-39,115;
/M: SY='Q';  M= -1,-80, 67, 14,-86,-66,-54,-78, 29,-76,-67,-17,-66, 89,-47,-52,-43,-51,-82,-67;
/M: SY='A';  M= 63,-68,-49, -5,-76,-59,-64,-24, 42,-68,-63,-10,-66,  9,-21,  8, 20,-34,-78,-69;
/M: SY='D';  M= 51,-73, 75, 21,-82,-61,-60,-50, 25,-76,-70,-20,-66,  1,-56,-38,-31,-68,-85,-71;
/M: SY='N';  M=-42,-72,-63,-62,-54,-72,-59,-32, 39, 49, -6, 56,-76,  1,-55,-62,-58, 11,-73, 23;
/M: SY='A';  M= 66,-68,-35, 16,-77,-59,-53,-38, 15,-64,-62,-31,-66, 39,-31,-10, 24,-28,-79,-69;
/M: SY='A';  M= 78,-66,-32,  3,-76,-56,-66,-43, -7,-57,-62,-31,-67, 15,-56, 15,-12,-19,-78,-70;
/M: SY='Y';  M= 29,-78,-66,-64,-35,-69, 32,-63,-40,-60,-55, -4,-77, 28,-60,-37,-62,-64,-42,112;
/M: SY='Q';  M= -4,-78, 32, 40,-81,-68,-55,-50, 11,-44,-63, 11,-66, 88,-24,-53,-17,-11,-80,-67;
/M: SY='A';  M= 55,-70,  4, 23,-78,-55,-61,-70, 25,-51,-64,-16,-65, 49,-54, -3, 24,-42,-79,-69;
/M: SY='E';  M= 22,-77, 25, 83,-80,-45,-57,-77, 20,-32,-68,-10,-62, -4,-52,-36,-55,-56,-81,-72;
/M: SY='Y';  M=-62,-73,-74,-67,-45,-39,-63,-16, 28, 38,-45,-69,-77,-12,-41,-42, -7, 47,-33, 62;
/M: SY='A';  M= 61,-69, 19, 23,-78,-58,-61,-71, 28,-73,-66, 35,-66, -9,-55,  2,-22,-29,-81,-71;
/I:         I=-36; MD=-90;
/M: SY='R';  M= -2,-81,-22, 34,-82,-73,-58,-72, 51,-77,-67,-55,-69, 44, 67,-57, -5,-74,-79,-68; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='Y';  M= 40,-71,-28, -7,-53,-72,-68, 49,-34,-42,-50,-67,-72,-43,-69,-44,  6, 38,-68, 50;
/M: SY='Q';  M=-62,-78, 37, 28,-81,-69,-55,-46, 49,-58,-65, 25,-66, 76,-24,-53, 15,-27,-81,-67;
/M: SY='A';  M= 67,-69,-15, 20,-77,-60,-64,-24, 22,-68,-62,-57,-66, 36,-31, -9,  3,-22,-78,-69;
/M: SY='E';  M= 59,-72, 16, 62,-46,-62,-61,-75, 29,-73,-67,-25,-63,-16,-41,-50,-14,-65,-79,-70;
/M: SY='N';  M=-65,-74,-24,-13,-32,-62,-46,-51, 25,-72,-64, 94,-21, 12,-53,-53,-55,-47,-66, 69;
/M: SY='A';  M= 61,-71, 37, -1,-80,-60,-62,-70, 38,-71,-65,-43,-66, 43,-52, -6,-26,-26,-80,-69;
/M: SY='A';  M= 73,-68,  6,  2,-78,-57,-63,-69, -5,-52,-63, -1,-67, 35,-34,-15,  8,-46,-79,-70;
/M: SY='A';  M= 74,-68,-69,-55,-60,-60,-64,  2, -8,-14,-55,-64,-70,  2,-39,-49,  9,-37,-67, 45;
/M: SY='K';  M=-43,-80, 49,-24,-53,-70,-56,-78, 78,-45,-66,-48,-66, 69,  2,-56,-60,-76,-77,-65;
/M: SY='A';  M= 69,-68, -6, 34,-76,-59,-64,-43, 10,-51,-63,-31,-66, -1,-28, 10,-25,-21,-79,-70;
/M: SY='Q';  M= 27,-76, 33, 35,-56,-65,-56,-77, 39,-75,-67, 10,-65, 64, -5,-25, -7,-71,-80,-68;
/M: SY='Y';  M=-70,-79,-69,-73,-26,-77,-14,-42,-66, -4,-49, 16,-83,-62,-65,-66,-63,  0,-37,121;
/M: SY='E';  M= 22,-78, 57, 84,-84,-43,-56,-82,-48,-78,-73,-13,-62, 15,-57,-32,-59,-74,-84,-73;
/M: SY='Q';  M=  1,-76,-52, 37,-78,-68,-57,-55, 63,-44,-62,-26,-64, 74,-21,-21,  5,-26,-76,-66;
/M: SY='D';  M= 50,-72, 62,  9,-75,-60,-57,-74, 47,-75,-68, 25,-66,-43,-51,-40,-41,-59,-79,  5;
/M: SY='L';  M=  2,-71,-66, -7,-57,-74,-38,-17, 30, 48, 31, -1,-73, 40,-28,-62,-58, 22,-75,-59;
/M: SY='A';  M= 85,-65,-61, 13,-76,-54,-66,-66,  6,-68,-62,-59,-65, -6,-18,-39, -5,-35,-76,-70;
/M: SY='A';  M= 57,-70,  1, 39,-77,-61,-61,-46, 38,-70,-64,-54,-63, 31,-29, -8, 13,-36,-78,-68;
/M: SY='Y';  M=-44,-29,  7,-29,-42,-67, 38,-18,-11,-46,-56, 66,-75,-27,-31,-56,-18,-29,-53, 96;
/M: SY='N';  M=-32,-73, 34,  8,-76,-52,-53,-63, 52,-41,-65, 63,-66, 51,-45,-17, 23,-67,-81,-37;
/I:         I=-12; MD=-29;
/M: SY='A';  M= 68,-76,-54,  2,-86,-42,-77,-50,  1,-77,-72,-70,-76,-14,-70,-37, -2,-21,-88,-80; D=-12;
/I:         I=-12; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='K';  M=  5,-93, 12, 33,-98,-83, 11,-95, 36,-92,-84,-20,-81, 25,-33,-69,-28,-89,-98,-84; D=-12;
/I:         I=-12; DM=-29;
/M: SY='N';  M=-77,-84,-61,-45,-43,-74,-27,-20,-10,-37,-70, 83,-87,-66,-40,-65,-27,-47,-77, 59; D=-12;
/I:         I=-12; DM=-29;
/M: SY='D';  M= 37,-83, 46, 21,-92,-72,-49,-86,  1,-86,-80, 14,-76,  6,-56,-60,  7,-78,-96,-81; D=-12;
/I:         I=-12; DM=-29;
/M: SY='A';  M= 45,-80,-32, 39,-75,-71,-69,-78,-10,-52,-72,-27,-74, 36,  2,-12,-11,-39,-87,-77; D=-12;
/I:         I=-12; DM=-29;
/M: SY='I';  M= 26,-79, -9,-52,-66,-77,-75, 52, 34,-18,-55,-40,-77,-10,-64,-37,-53,  6,-80, -6; D=-12;
/I:         I=-12; DM=-29;
/M: SY='Q';  M=  1,-79,-46, 20,-75,-47,-67,-18, 24, -7,-18, -1,-74, 55,-58,-39,  6, 13,-84,-71; D=-12;
/I:         I=-12; DM=-29;
/M: SY='A';  M= 85,-65,-41,  5,-75,-54,-65,-65,-11,-50,-61,-59,-65, 23,-60,-10,-15,-36,-76,-44;
/M: SY='E';  M= -7,-78, 43, 86,-80,-70,-55,-66, 16,-75,-70,-51,-60, 33,-50,-53,  4,-73,-80,-26;
/M: SY='N';  M=-45,-71,-48,-37,-29,-60,-48,-55, 46,-36,-60, 92,-73,-51,-43,-35,-53,  1,-68, 59;
/M: SY='A';  M= 56,-69,  7, 55,-76,-53,-60,-69,-14,-43,-64,  8,-63, 21,-41,-25, 31,-46,-80,-69;
/M: SY='A';  M= 70,-70,-58, 25,-75,-59,-60,-70,  9,-69,-62,-58,-66, 48, 29,-30,-29,-43,-74,-19;
/M: SY='I';  M= 37,-73, -7, -5,-55,-73,-71, 75,-25,-33,-46,-67,-71,-28,-70,-39,-41, 13,-71, 24;
/I:         I=-36; MD=-90;
/M: SY='Q';  M=-36,-80, 39, 10,-56,-71,-58,-74, 56,-41,-20,  3,-69, 57, 23,-44, -4,-35,-81,-67; D=-36;
/I:         I=-36; MD=-90;
/M: SY='K';  M= 51,-73,-58, 19,-81,-54,-62,-75, 57,-74,-31,-37,-66, 49,-37,-14, -2,-67,-78,-70; D=-36;
/I:         I=-36; MD=-90;
/M: SY='R';  M= 40,-77, 14, 16,-47,-53,-61,-48, -1,-60,-67,-19,-72, 28, 56,-27,-15,-46,-79,-17; D=-36;
/I:         I=-36; MI=-90; MD=-90; IM=-90; DM=-90;
/M: SY='N';  M=-67,-74,-46,-64,-52,-60,-43,-71,-55,-74,-27,106,-79,-55,-61,-52,-54,-75,-65, 81; D=-36;
/I:         I=-36; DM=-90;
/M: SY='A';  M= 65,-70, 30, 38,-78,-47,-59,-55,-23,-52,-64,  1,-65, 48,-34,-47,-12,-48,-79,-69;
/M: SY='Q';  M= 46,-71,  3, 21,-77,-62,-59,-63, 28,-51,-62,-38,-64, 64,-20,  6, 29,-37,-78,-67;
/M: SY='A';  M= 80,-50,  0,-39,-71,-55,-66,-42, 26,  0,-58,-38,-41,-56,-54,-13,-53,-54,-76,-68;
/M: SY='K';  M=-62,-79,-54, 23,-52,-71,-29,-73, 86,-15,-61,-52,-65, 62, 10,-57,-60,-72,-14,-41;
/M: SY='A';  M= 82,-64,-39,  7,-75,-21,-67,-63,-10,-67,-62,-59,-40,-27,-63, -2,  5, -8,-77,-70;
/M: SY='D';  M= 39,-72, 59, 31,-78,-63,-58,-48, 30,-50,-66,  7,-65, 23,-35,-33, 12,-30,-83,-68;
/M: SY='Y';  M=-71,-82,-70,-72, -4,-77,-38,-57,-31,-54,-50,-39,-83,-60,-61,-66,-65,-62, 12,132;
/M: SY='E';  M= -7,-79, 61, 77,-84,-68,-39,-81, -3,-77,-71,  5,-41, 53,-51,-53,-39,-76,-83,-70;
/M: SY='A';  M= 67,-66,-60, -9,-73,-58,-63,-55, 25,-41,-60, -6,-66, 33,-30, -3, 20, -1,-78,-67;
/M: SY='A';  M= 66,-69, 28,  6,-78,-58,-61,-72, 51,-52,-64,-53,-65, 26,-49, -8,-54,-63,-77,-69;
/M: SY='L';  M=-64,-71,-72,-28,-28,-79,-63,-38, 30, 66, 46,-69,-75, 36,-35,-65,-25, -2,-72,-56;
/M: SY='A';  M= 81,-65,-62,  2,-74,-55,-67,-28, 21,-61,-60,-37,-65,-24,-58,-14,  3,-15,-77,-69;
/M: SY='Q';  M= 14,-77,  1, 32,-80,-67,-55,-45, 32,-69,-61,-15,-65, 92,-17,-33,-25, -6,-77,-65;
/M: SY='Y';  M=-71,-81,-69,-72, -5,-77,-38,-58,-15,-55,-51,-13,-82,-60,-60,-65,-65,-63,-30,130;
/M: SY='Q';  M=-21,-78, 30, 63,-83,-66,-52,-78, 16,-76,-67, 43,-63, 76,-48,-51,  1,-75,-81,-68;
/M: SY='Q';  M= 43,-71, -1, 26,-78,-62,-60,-70, 47,-71,-64,-31,-64, 51,-48,  2, 31,-34,-78,-68;
/M: SY='D';  M= 42,-75, 85, 21,-83,-57,-57,-78, 23,-77,-72,-32,-65, 11,-31,-51,-31,-71,-86,-70;
/M: SY='K';  M=-64,-74, -9,-31,-57,-76,-62,-46, 65, 52,-46,-61,-62, 10, -5,-35,-31, -6,-72,-11;
/M: SY='A';  M= 87,-64,-64,-23,-76,-52,-67,-38,  5,-68,-62,-59,-57,-13,-61, 17,-35,-55,-76,-70;
/M: SY='A';  M= 56,-71, -5, 31,-77,-62,-24,-69, 27,-70,-36,-20,-65, 40, 17,-25,  5,-23,-78,-68;
/M: SY='Y';  M=-36,-78,-73,-73,-13,-78,-49, 32,-27,-30,-30,-20,-80,-31,-65,-66,-62, 18,  2,112;
/M: SY='D';  M= -6,-78, 70, 33,-82,-66,-54,-77, 41,-56,-69, 24,-65, 53,-14,-53,-31,-51,-84,-68;
/M: SY='K';  M= 34,-73,-40, 13,-77,-64,-58,-71, 62,-38,-30,-15,-65, 62,-13,-28, 22,-66,-76,-66;
/M: SY='A';  M= 65,-69, 26, 39,-73,-36,-62,-44,  5,-59,-64,-20,-65,-52,-59, -7, -3,-20,-77, -4;
/M: SY='N';  M=-63,-72,-21,-56,-23,-69,-56,-54, 56, 31, 24, 63,-73,  0, -4,-59,-56,  1,-76,-14;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 32 in 8 different sequences
Number of true positive hits 32 in 8 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 6
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] REPEAT
Feature description [info] Ag I/II A
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
8 sequences

PAA_STRCG   (Q9LBG3), PAC_STRMG   (P11657), PAS_STRIT   (Q9KW51), 
SPAA_STRDO  (P21979), SPAP_STRMU  (P23504), SSPA_STRGC  (A8AUS0), 
SSPB_STRGC  (A8AUS1), SSPB_STRGN  (P16952)
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PDB
[Detailed view]
4 PDB

2WD6; 6E36; 6TZL; 6UBV