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PROSITE entry PS51990


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General information about the entry

Entry name [info] COV_NSP2_M
Accession [info] PS51990
Entry type [info] MATRIX
Date [info] 25-MAY-2022 CREATED;
25-MAY-2022 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51989
Associated ProRule [info] PRU01334

Name and characterization of the entry

Description [info] Coronavirus (CoV) Nsp2 middle domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=232;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=227;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5488486; R2=0.0071232; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=976; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=555; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-40; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='C';  M= -62,  89,   7, -52, -69, -70, -56,  -5,  -3, -68, -61,  10, -74,  73,  48,  -8, -59, -67, -75,  23;
/M: SY='H';  M= -15, -73,  34, -62, -64,  40,  67, -48, -65,  12, -52, -57, -73, -63, -15, -59, -59,  52, -84, -60;
/M: SY='N';  M=  15, -70,  39, -54, -78,  18, -52, -77, -51, -80, -71,  90, -70, -52,  10,  25, -50, -74, -88, -71;
/M: SY='L';  M=  -4, -71, -84, -77, -44, -83, -73,  59, -77,  74, -32, -80, -80, -71, -76, -72, -61, -33, -72, -55;
/I:         I=-15; MD=-37;
/M: SY='N';  M= -74, -82,  15,  31,  10, -72,  43, -76, -62,  -1, -69,  80, -80, -60, -68, -63, -64, -79, -92, -67; D=-15;
/I:         I=-15; MD=-37;
/M: SY='Q';  M= -83, -95, -89, -77,  50, -96, -82,  33, -78, -67, -68, -81, -91,  67, -79, -78,   6, -66, -81, -63; D=-15;
/I:         I=-15; MD=-37;
/M: SY='V';  M= -78,  40, -90, -86, -80, -97, -87, -58, -73, -12, -69,   7, -99, -81,  40, -82, -75,  49,-104, -83; D=-15;
/I:         I=-15; MD=-37;
/M: SY='G';  M=  -1, -95,  11,   8,-100,  39,  30,-101, -75, -97, -88,  10, -86,  20, -80, -69, -80, -96,-100, -87; D=-15;
/I:         I=-15; MD=-37;
/M: SY='D';  M= -83, -97,  43,  22, -86, -91, -77,  26, -75, -10, -74,  16, -88,  20, -81, -78, -77, -72,-102, -83; D=-15;
/I:         I=-15; MD=-37;
/M: SY='F';  M= -10, -80, -92, -85,  88, -87, -77, -55, -85,  31, -54, -86,  17, -88, -84, -79, -73, -60, -61, -42; D=-15;
/I:         I=-15; MD=-37;
/M: SY='G';  M=  -5, -82, -68,   3, -83,  40,  24, -73,  32, -78, -71, -63, -76,  -7, -13, -61,   8,  13, -88, -75; D=-15;
/I:         I=-15; MD=-37;
/M: SY='L';  M= -65,  42, -81, -75,  -8, -10, -76, -46,  16,  48, -49, -75, -84, -72, -71,  -1, -63,  36, -82, -64; D=-15;
/I:         I=-15; MD=-37;
/M: SY='N';  M=  -4, -74,  19, -58, -80, -64, -60, -74,   3, -77,  18,  71, -72,  18, -61,  10,  46, -71, -92, -73; D=-15;
/I:         I=-15; MD=-37;
/M: SY='P';  M= -66, -84,  56,  61, -86, -71, -61, -81, -55, -83, -76,  12,  75, -53, -65, -59,  10, -79, -89, -78; D=-15;
/I:         I=-15; MD=-37;
/M: SY='W';  M= -63, -80, -72,  36,  16, -78, -80, -51, -67, -60, -62, -75, -75, -65, -72,  -4,   3,  50, 125, -48; D=-15;
/I:         I=-15; MD=-37;
/M: SY='W';  M= -68, -78, -89, -83,  71, -85, -78,  26, -78, -46, -51, -82, -84, -81, -79, -75, -65,  53,  94,  35; D=-15;
/I:         I=-15; MD=-37;
/M: SY='H';  M=  40,  35, -76, -71, -62, -73,  71,   3, -72,  10, -50, -69, -78, -68, -72, -62, -59,  52, -87, -61; D=-15;
/I:         I=-15; MD=-37;
/M: SY='R';  M=  29, -78, -65, -56, -74, -70, -62,  33,  31, -66, -60,  18, -73,  38,  62, -58, -61, -58, -79, -67; D=-15;
/I:         I=-15; MD=-37;
/M: SY='Q';  M= -66, -81, -69, -56, -66, -80, -66,  56,  58,  12, -50, -63, -73,  68, -49, -65, -63, -48, -75, -63; D=-15;
/I:         I=-15; MD=-37;
/M: SY='L';  M=  -8,  57,  10, -73, -50, -82, -71, -43, -78,  76, -39, -77, -85, -73, -77, -73, -65, -48, -79, -61; D=-15;
/I:         I=-15; MD=-37;
/M: SY='G';  M=  25, -88, -77,   0, -98,  41, -84, -97, -80, -97, -89, -71, -84, -74, -86,  38, -71, -88, -97, -92; D=-15;
/I:         I=-15; MI=-37; MD=-37; IM=-37; DM=-37;
/M: SY='S';  M=   7, -89,  33, -74, -99,  32, -82, -98, -80, -99, -92, -66, -86, -76, -86,  46, -69, -90,-101, -90; D=-15;
/I:         I=-15; DM=-37;
/M: SY='F';  M= -83, -88, -95, -94,  46,-100, -90,  19, -91,  21, -62, -87, -94, -92, -93, -79,  43, -60, -84, -64; D=-15;
/I:         I=-15; DM=-37;
/M: SY='F';  M=  -9, -72, -77, -75,  48, -76, -74, -54, -74,  31, -55, -68, -79, -72, -76,  34,  44,  -4, -75, -56; D=-15;
/I:         I=-15; DM=-37;
/M: SY='C';  M=  36,  43, -71, -69, -67,  -3, -73, -27, -69,   7, -57, -62, -73, -66, -73,  41,  27,  24, -84, -69; D=-15;
/I:         I=-15; DM=-37;
/M: SY='N';  M=  -8, -72,  47, -55, -79, -59, -58, -71, -58, -78, -72,  71,  16, -57, -66,  47,  11,  -8, -93, -73; D=-15;
/I:         I=-15; DM=-37;
/M: SY='R';  M=   8,  39, -72, -66,  13, -74, -68,  -2, -55, -61,  30, -64,  30, -62,  53, -57,  49,  -9, -79, -63; D=-15;
/I:         I=-15; DM=-37;
/M: SY='W';  M= -61,   5,   1,  27, -67,  41, -74, -83,   5, -80, -76, -62, -72, -59, -66,  27, -66, -83, 125, -56; D=-15;
/I:         I=-15; DM=-37;
/M: SY='D';  M=  50, -71,  53,  44, -77, -62, -61, -67,  34, -71, -66, -52, -64, -49, -54,   4, -54,   2, -82, -69;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='Y';  M= -66, -72, -82, -78,  61, -83, -62,   2, -75,  47, -40, -78, -83, -73, -73, -72, -62,  34, -52,  72;
/M: SY='R';  M=  -4, -73, -59,  20, -69,  -2, -63,  12,  31, -61, -57,  11, -69, -52,  46,  10, -55,  39, -79, -65;
/M: SY='D';  M=  32, -74,  55,  43, -73, -64,  39, -68, -55,  -6,  29, -53,  23,  14, -61,   3, -57, -65, -83, -65;
/M: SY='L';  M=  -5, -66, -72, -69, -52,  -8, -69, -42, -69,  63, -41, -65, -73, -66, -71,   5,  55,  -1, -77, -60;
/M: SY='C';  M= -60,  82, -83, -78, -50, -84, -77,   4, -77,  54, -39, -78, -83, -76, -77, -70, -57,  63, -82, -61;
/M: SY='K';  M= -61,  25, -50,  52, -78, -10,  38, -80,  66, -75, -66, -51, -64,  20,  33, -55,   9, -74, -78, -65;
/M: SY='N';  M= -52, -70, -47,   7, -79,  43, -53, -79, -53, -81, -70,  81, -67,  22, -60,  57, -48, -75, -83, -71;
/I:         I=-6; MD=-15;
/M: SY='L';  M=  16, -72, -85, -78, -51, -81, -75,  31, -78,  61,  33, -80, -81, -73, -77, -71, -62,  26, -78, -60; D=-6;
/I:         I=-6; MD=-15;
/M: SY='D';  M= -79, -94,  79, -61,-102, -10, -78, -99, -77, -99, -96, -59, -85, -76, -85,   1,  24, -93,-114, -90; D=-6;
/I:         I=-6; MD=-15;
/M: SY='Y';  M= -90, -95, -97, -96,  12,-102, -70, -64, -91,  35, -60, -97,-104, -87, -88, -91, -85, -71, -62,  85; D=-6;
/I:         I=-6; MD=-15;
/M: SY='F';  M= -87, -95,  -1,  26,  58, -96, -81, -81,  34, -19, -77, -80, -90, -74, -70, -84, -82, -83, -81, -63; D=-6;
/I:         I=-6; MD=-15;
/M: SY='K';  M= -19, -88, -78, -75, -90, -82, -82, -74,  38, -85, -80,  20, -88, -72, -69,  29, -21,  22,-102, -86; D=-6;
/I:         I=-6; MD=-15;
/M: SY='F';  M= -84, -92,   2, -81,  46, -97, -85, -64,  28, -20,  39, -83, -94, -83, -75, -86, -79,  18, -86, -65; D=-6;
/I:         I=-6; MD=-15;
/M: SY='R';  M= -85,-101, -77,   0, -97, -95, -74,-102,  37, -96, -85, -74, -90, -59,  78, -80, -83, -96, -95, -84; D=-6;
/I:         I=-6; MD=-15;
/M: SY='D';  M= -83, -97,  53, -65, -95, -92, -77, -83, -62, -89, -84, -69, -91,   7,  53, -76,  -4,   5,-106, -85; D=-6;
/I:         I=-6; MD=-15;
/M: SY='Y';  M=  37, -78, -73, -67, -62, -75,  37,  34,  37, -62, -59, -67, -76, -64, -61, -61,   1,  -4, -73,  43; D=-6;
/I:         I=-6; MD=-15;
/M: SY='L';  M= -68, -78,   3,  10, -59, -88, -76,   4,   6,  48, -47, -76, -82, -69, -71, -74, -65,  43, -85, -66; D=-6;
/I:         I=-6; MD=-15;
/M: SY='F';  M= -15,  35, -68,  36,  69, -81, -73, -62, -69, -61, -64, -68, -76, -70, -74, -61,  53,  -2, -72, -52; D=-6;
/I:         I=-6; MD=-15;
/M: SY='S';  M=  21, -75,   1, -65, -70,  -6, -64, -76, -66, -78, -72,  17,  12, -63, -71,  50,  31, -70, -78,  39; D=-6;
/I:         I=-6; MD=-15;
/M: SY='C';  M= -78, 103, -89, -83, -82,  -8, -88, -82,  33,  10, -74, -79, -96, -82, -75, -80, -78, -79,-100, -87; D=-6;
/I:         I=-6; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='H';  M= -85,-105, -81,   7, -93,  27,  36,-107,   2,-100, -91, -78, -94, -73,  28, -82, -90,-103, -95,  11; D=-6;
/I:         I=-6; DM=-15;
/M: SY='K';  M= -62, -74,   3, -58, -72,  20, -63, -65,  55,   9, -61,  50, -71, -57, -53, -55,  33, -15, -83, -69; D=-6;
/I:         I=-6; DM=-15;
/M: SY='F';  M= -74, -76, -89, -84, 101, -85, -70, -47, -80,  -8, -52, -81, -87, -85, -78, -76, -68,  19,  60,  38; D=-6;
/I:         I=-6; DM=-15;
/M: SY='A';  M=  43, -72, -72, -64, -63, -70, -70,   0,  35, -11, -56, -67,  18, -63, -61, -57,  14,  32, -75,  19; D=-6;
/I:         I=-6; DM=-15;
/M: SY='V';  M=  -7, -68, -73, -73, -63, -77, -79, -33, -70, -51, -52,  14, -75, -73, -74, -57,  52,  81, -91, -67; D=-6;
/I:         I=-6; DM=-15;
/M: SY='C';  M=  17,  89, -69, -68, -71, -70, -74, -66, -67, -16, -63, -59,  10, -69, -74,  -6,  78, -58, -90, -73; D=-6;
/I:         I=-6; DM=-15;
/M: SY='T';  M=  18, -71,   4, -58,  11,  24, -63,   3,  18, -60,  29,  -5, -68,  24, -17,  -7,  32,  -4, -75, -60;
/M: SY='G';  M= -55, -75,  67, -54, -82,  73, -61, -84, -61, -83, -75,  34, -67, -60, -69,   2,   5, -79, -84, -73;
/M: SY='G';  M=  -7, -73,  11, -59, -70,  41, -66, -56,  29, -10, -59, -56,   7, -58,  17,  19, -56,  36, -79, -67;
/M: SY='F';  M=  -2,  42, -80, -75,  75, -77, -65, -45, -73,  31, -47, -75,  26, -74, -73, -68, -62,  14, -55,  51;
/M: SY='V';  M= -58, -71, -75, -66, -56, -80, -71,  37,  50,  -3,  62, -68, -73, -62, -56, -66, -55,  66, -78, -59;
/M: SY='P';  M=  -3, -77,  43,   4, -79, -65, -59, -75,  28, -77, -69,  14,  64, -51,  36,   1,  23, -71, -82, -71;
/M: SY='F';  M=  -6, -71,  11, -69,  67,  41, -63, -55, -69,  35, -52,  38, -77, -68, -71, -60, -62, -58, -64, -47;
/M: SY='A';  M=  47,  36, -76, -68, -56, -70, -73,   7,   3,  41, -44, -71, -75, -66, -67, -59, -56,  45, -78, -62;
/I:         I=-13; MD=-33;
/M: SY='W';  M= -81, -97,  24, -73, -72, -88, -84,  50,   2, -69, -69,   9, -86,  18, -76, -79, -77, -63, 101, -65; D=-13;
/I:         I=-13; MD=-33;
/M: SY='N';  M= -90, -97, -71, -83,-101, -85, -75, -96,  15, -98,  34,  79, -99, -77, -77, -78, -78, -99,-115, -95; D=-13;
/I:         I=-13; MD=-33;
/M: SY='C';  M= -90,  56,-112,-109, -80,-114,-110,  47,-106, -11, -69,-104,-108,-105,-109, -99, -86,  15,-109, -89; D=-13;
/I:         I=-13; MD=-33;
/M: SY='G';  M= -78,-103, -96,-104,-104,  66,-102, -93, -99,-100, -95, -83, -98, -97,-105, -80, -92,   7,-104,-102; D=-13;
/I:         I=-13; MD=-33;
/M: SY='Q';  M=  13,-103,  10,  -9,-111, -17, -86,-105,  15,-103, -94, -79, -93,  40, -76, -78, -86, -98,-105, -96; D=-13;
/I:         I=-13; MD=-33;
/M: SY='Q';  M= -15,-101, -84, -28,-100, -94,   3, -17,   2, -91, -85,  14, -95,  36, -79, -79,  -5, -14,-109, -91; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='F';  M=  28, -78, -81, -74,  48, -80, -74, -61,   6,  30, -57, -75, -83, -71,  17, -67,   8, -61, -74, -58; D=-13;
/I:         I=-13; DM=-33;
/M: SY='D';  M=  11, -79,  87,   5, -87, -66, -63, -84, -61, -84, -81, -48, -71, -58, -69,  35,   9, -77, -98, -76; D=-13;
/I:         I=-13; DM=-33;
/M: SY='I';  M= -66,  39,  14,   4,   9,  22, -79,  48, -76, -12, -56, -70, -80, -74, -80, -70, -66,  29, -82, -66; D=-13;
/I:         I=-13; DM=-33;
/M: SY='F';  M=  -9, -74, -76, -78,  62, -79, -69, -50, -76,  53, -48,  39, -85, -75, -77, -69,  -2, -55, -70, -50; D=-13;
/I:         I=-13; DM=-33;
/M: SY='T';  M=  30, -69, -66,   0, -68, -70,  38,   0, -65, -59, -57, -61, -70, -64, -70,  -5,  62,  43, -88, -66; D=-13;
/I:         I=-13; DM=-33;
/M: SY='P';  M= -64, -89, -63,   6, -88, -69, -67, -78, -60, -84, -72, -67, 109,  37, -69,  23, -59, -80, -82, -80; D=-13;
/I:         I=-13; DM=-33;
/M: SY='F';  M= -10, -75, -75, -69,  55, -77, -65,  -3, -57,  20, -53, -67, -78, -63,  53,  -2,  26, -55, -65,  17; D=-13;
/I:         I=-13; DM=-33;
/M: SY='C';  M=   0,  98, -79, -78, -59, -75, -75,  58, -75, -54, -55, -69, -80, -73, -78,  28, -57,  -5, -78,  28; D=-13;
/I:         I=-13; DM=-33;
/M: SY='Y';  M=  14, -74,  31, -65, -54,  15, -62, -55, -67, -62, -60, -60, -74, -67, -71, -55,  42,  34, -66,  71; D=-13;
/I:         I=-13; DM=-33;
/M: SY='Y';  M= -11,  35, -82, -81,  62,  -4, -64,  36, -76,   8, -50, -75, -83, -76, -76, -70, -66, -50, -53,  72; D=-13;
/I:         I=-13; DM=-33;
/M: SY='L';  M=  36, -71, -75, -69, -59, -71, -71, -51, -71,  55, -47, -71,  37, -67, -74,  -1,  29, -52, -79, -66; D=-13;
/I:         I=-13; DM=-33;
/M: SY='G';  M=  24, -74, -69, -70, -74,  59, -73,  28,  -2, -68, -64, -58, -71, -64, -70,  35, -58,  -5, -79, -72; D=-13;
/I:         I=-13; DM=-33;
/M: SY='V';  M= -80, -90, -97, -90, -65,-102, -88,  -1,   6,  22, -59, -93, -97, -86, -83, -88, -76,  45, -88,  24; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='G';  M=   7, -92, -86, -92, -97,  71, -91, -90, -88, -94, -87, -74, -88, -86, -95, -69, -82,  -6, -95, -94; D=-13;
/I:         I=-13; DM=-33;
/M: SY='Q';  M= -63, -84, -51,  52, -88, -73, -55, -82,  59, -77, -67, -54, -65,  94, -39, -56, -63, -80, -77, -68; D=-13;
/I:         I=-13; DM=-33;
/M: SY='A';  M=  61,  57, -67, -63, -77, -57, -68, -73, -60, -74, -68, -58, -71, -59,   9,  59,   7, -62, -84, -73; D=-13;
/I:         I=-13; DM=-33;
/M: SY='F';  M=  39, -72, -83, -79, 103,  -9, -72, -57, -77, -51, -58, -74, -82, -81, -77, -65, -66, -58, -52, -33; D=-13;
/I:         I=-13; DM=-33;
/M: SY='C';  M=  -7,  73,  10, -59, -71,  16, -66,  -3,  39, -66, -62,  13, -70, -58,  -1,   5,  16,  12, -83, -69;
/M: SY='K';  M= -61, -74,  16, -55,   9, -73, -67,   6,  68,   3, -54, -58, -71, -55, -48,   9, -56,  30,  66, -55;
/M: SY='V';  M=  -3, -71, -78, -76,  12,  10, -68,  40, -72, -19,  23, -72, -77, -71, -74, -64, -57,  61, -64,  56;
/M: SY='A';  M=  47, -69, -66, -63,  11,  36, -63, -67, -54, -65,  42, -56, -69, -56,  42,  33,   4, -61, -73, -62;
/M: SY='S';  M=  34, -67,  45, -52, -74, -18, -63, -64,  18, -70, -65, -48, -65, -54, -59,  57,  31,   5, -83, -68;
/I:         I=-8; MD=-21;
/M: SY='Y';  M= -71, -81, -80, -81, -43, -87, -64,  57, -76,  13, -47,  -9, -83, -73, -77, -72,   2,   4, -59,  82; D=-8;
/I:         I=-8; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='P';  M=  -5, -84, -79, -72,  54, -74, -75, -71, -74, -70,  28, -74,  74, -74, -80,  39, -63, -72, -75, -61; D=-8;
/I:         I=-8; DM=-21;
/M: SY='W';  M= -35, -83,   5, -63, -72, -69, -70, -83,  22, -83, -77, -61, -77,   8, -63,  64, -18, -80,  91,  14; D=-8;
/I:         I=-8; DM=-21;
/M: SY='R';  M= -68, -84, -62, -50, -81, -76, -56, -84,  56, -79, -67,   4, -74,  20,  93, -61, -65, -79, -78, -67; D=-8;
/I:         I=-8; DM=-21;
/M: SY='T';  M= -28, -70, -73, -19,  30, -80, -77,  27, -70,  -2, -50, -67, -73, -72, -75, -57,  66,  46, -78, -57; D=-8;
/I:         I=-8; DM=-21;
/M: SY='C';  M= -63,  96, -60,  59,  14, -78, -68, -64, -64,  19, -60, -67, -75, -60, -70,  17, -61, -21, -82, -66; D=-8;
/I:         I=-8; DM=-21;
/M: SY='H';  M= -61, -76,  32,  26,   7, -67,  62, -74, -54, -73, -68,  36, -70,  18,   8,  37,   3, -25, -86, -60; D=-8;
/I:         I=-8; DM=-21;
/M: SY='A';  M=  61, -66,  29,  22, -77, -54, -61, -71, -56, -73, -67,  18, -64, -52, -62,  50,  15, -61, -82, -70;
/M: SY='V';  M=  27, -66, -70, -69,  17, -69, -67, -39, -67,  13,  14,  11, -73, -66, -70,   0,  30,  55, -73,  11;
/I:         I=-15; MD=-38;
/M: SY='N';  M=  -7, -77, -67, -64,  13, -73, -67,  16,  25, -64, -61,  36, -76,   9,  33,  -2,  -4,  18, -80, -63; D=-15;
/I:         I=-15; MD=-38;
/M: SY='D';  M= -64, -78,  58,   3, -81, -66,  58, -77,   5, -80, -73,  52, -73, -55, -61,  36, -56,  -7, -97, -68; D=-15;
/I:         I=-15; MD=-38;
/M: SY='L';  M=  -7, -81, -85, -82,  14, -83, -81, -62, -82,  40, -60, -77, -87, -78, -84,  33,  25, -64, -86, -69; D=-15;
/I:         I=-15; MD=-38;
/M: SY='V';  M= -81, -91, -98, -93, -73,-104, -96,  22,  -7,  22, -61, -92, -97, -90, -88, -86,   4,  33,-100, -80; D=-15;
/I:         I=-15; MD=-38;
/M: SY='D';  M= -78, -90,  33, -70, -83, -85, -74,  -1, -67, -34,  28,  30,  22, -71,  28, -73,  -3,  -8, -99, -80; D=-15;
/I:         I=-15; MD=-38;
/M: SY='Y';  M=  -9, -87,  29, -70, -70, -85,  30, -66,  16, -74, -71, -70, -86, -73, -71, -71,   8,  29, -84,  46; D=-15;
/I:         I=-15; MD=-38;
/M: SY='Y';  M= -79, -89,  31,   4, -60, -89, -68, -63, -77,  18, -64,  13, -90, -74, -80, -78, -74,  10, -76,  62; D=-15;
/I:         I=-15; MD=-38;
/M: SY='Q';  M=  10,  11,  26,  44, -97, -78, -69, -92, -63, -90, -82,  14, -79,  56, -69, -19, -71, -87, -97, -84; D=-15;
/I:         I=-15; MD=-38;
/M: SY='D';  M= -78, -94,  56,  29, -84, -83,  26, -95,  -8, -90, -84, -62, -82, -61,  28,   1, -73, -91, -91,  21; D=-15;
/I:         I=-15; MD=-38;
/M: SY='S';  M=  25, -81, -78, -78,   6, -75, -79, -66, -72, -75, -73,  15, -86, -73,   8,  37, -63,  28, -92, -74; D=-15;
/I:         I=-15; MD=-38;
/M: SY='V';  M=  24, -84, -88, -81,  13, -85, -89,  25,  -1, -65, -66, -81,  10, -81, -81, -71,   2,  27, -88, -72; D=-15;
/I:         I=-15; MD=-38;
/M: SY='M';  M=  15, -82, -91, -86, -67, -88, -85,   8, -85,  33,  35, -84, -88, -82, -87, -73,  22,   8, -92, -74; D=-15;
/I:         I=-15; MI=0; MD=-38; IM=0; DM=-38;
/M: SY='V';  M= -71, -85,  47, -67, -82, -88, -82, -57, -75, -71, -71, -68, -84,  21, -80, -68,  40,  51,-104, -80; D=-15;
/I:         I=-15; DM=-38;
/M: SY='I';  M= -13, -87, -97, -93,  14, -96, -93,  66, -89, -52,  25, -88, -89, -88, -92, -81, -17,  23, -87, -67; D=-15;
/I:         I=-15; DM=-38;
/M: SY='P';  M= -74, -85,  -3, -80,  15, -92, -85,  40, -84,  20, -54, -84,  41, -83, -87, -80, -69,  33, -84, -66; D=-15;
/I:         I=-15; DM=-38;
/M: SY='C';  M= -66,  66,  56, -68, -92,  61, -76, -97, -76, -93, -87, -58, -81, -75, -83,  -7, -72, -90, -96, -86; D=-15;
/I:         I=-15; DM=-38;
/M: SY='D';  M= -70, -88,  77, -56, -95,  45, -69, -96,   4, -95, -88,  13, -78, -66, -71, -22, -69, -92, -98, -83; D=-15;
/I:         I=-15; DM=-38;
/M: SY='M';  M= -57,  16, -81, -73, -53, -82, -73,  39, -71,  -4,  80, -74, -76,  15, -71, -67, -55,  72, -80, -58;
/M: SY='C';  M=  49,  80, -62, -60, -73, -56, -65, -69,   5, -69,  10,  -5, -68, -57, -62,  63,   7, -60, -83, -69;
/M: SY='F';  M=  -4, -73,  35,  25,  71, -70, -57, -60,   9, -13,  21,  -5, -72,  10, -59,  -6, -59, -61, -60,  26;
/I:         I=-20; MD=-51;
/M: SY='F';  M= -69, -79,  -4, -62,  73, -76, -56, -63,  26, -57,  11, -64, -78,  42, -58,   7, -63, -66, -52,  70; D=-20;
/I:         I=-20; MD=-51;
/M: SY='M';  M= -21,  35, -64,   1, -71, -69, -65, -59,  40, -63,  52, -58, -71, -55,  11,  45,   5,  22, -84, -67; D=-20;
/I:         I=-20; MD=-51;
/M: SY='S';  M=  10,  34, -62,  45, -72, -70, -69, -67, -65,  25, -62, -64, -74, -58, -70,  57, -57, -65, -86, -72; D=-20;
/I:         I=-20; MD=-51;
/M: SY='D';  M= -72, -82,  49,  -8, -65, -13, -68,  -2, -61,  47, -54, -66, -81, -64,  41, -72, -69, -60, -85, -68; D=-20;
/I:         I=-20; MD=-51;
/M: SY='L';  M= -69, -79, -76,  17,  -6,  33, -73, -52, -77,  65, -47, -77, -83, -71, -78, -73, -71, -57, -77, -64; D=-20;
/I:         I=-20; MD=-51;
/M: SY='Y';  M= -78, -84, -93, -89,  59, -94, -72,   9, -85,  26,  13, -88, -93, -84, -83, -83, -73,   8, -61,  60; D=-20;
/I:         I=-20; MD=-51;
/M: SY='D';  M= -81, -91,  74, -62,  13, -84, -62, -73, -74, -12,  19, -64, -87, -72, -77, -75, -73, -77, -70,  71; D=-20;
/I:         I=-20; MD=-51;
/M: SY='C';  M=  24,  80, -87, -81,  26,  -5, -81, -86, -68, -81, -78, -77, -92, -77,  46, -71, -76, -79, -88, -74; D=-20;
/I:         I=-20; MD=-51;
/M: SY='M';  M= -93,-100,   7, -91,   6,-103,  30, -72, -94, -13,  89, -89,-101, -88, -93, -96, -89, -78,-101, -73; D=-20;
/I:         I=-20; MI=-51; MD=-51; IM=-51; DM=-51;
/M: SY='M';  M= -88, -98,-109,-102, -72,-106, -85, -61, -97, -14,  91,-101,-103, -91, -95, -98, -86,  15, -94,  23; D=-20;
/I:         I=-20; DM=-51;
/M: SY='Y';  M=  37, -95, -98, -94,  -2, -88, -88, -81, -93, -85, -83, -93,-100, -90, -95,  -8, -81,  -5, -85,  43; D=-20;
/I:         I=-20; DM=-51;
/M: SY='T';  M= -81, -95,  30, -80, -96, -90, -89, -90, -87, -17, -89, -74, -93, -84, -93,  34,  39, -87,-114, -93; D=-20;
/I:         I=-20; DM=-51;
/M: SY='P';  M=  14, -79, -71, -67, -79,  -3,  44, -71, -65, -74,  28, -63,  53, -64,   3,  35,   9, -13, -88, -71; D=-20;
/I:         I=-20; DM=-51;
/M: SY='D';  M= -68, -80,  96,  11, -85, -67, -56, -78,   5, -82, -78,  48, -70, -55, -61, -57, -58, -11, -99, -73; D=-20;
/I:         I=-20; DM=-51;
/M: SY='L';  M= -62, -72, -76, -73,   8, -78, -70, -40, -69,  55, -44,  16, -82, -68,   2,  19, -58,  42, -78, -58; D=-20;
/I:         I=-20; DM=-51;
/M: SY='V';  M=  15, -67, -69, -64, -62, -69, -71, -40,  10,   8, -50, -63,  19, -63, -64,  27,  32,  60, -81, -64;
/M: SY='V';  M= -57, -69, -75, -73, -52, -10, -74,  43, -71,  43, -41, -68, -74, -69, -74,  -2,  41,  45, -78, -60;
/M: SY='N';  M=  45, -66,  18,   2, -71, -60, -61, -55, -57, -65, -61,  65, -68, -57, -64, -46,  46,  32, -87, -69;
/M: SY='S';  M=  -6, -66, -54, -58, -73,   1,  33, -72, -53, -74, -66,  48, -65, -52,  10,  67,  53, -65, -85, -65;
/I:         I=-38; MD=-97;
/M: SY='C';  M= -12,  42, -85, -80, -73, -86, -84, -60,   7,  25, -62, -77, -87, -78, -77,   1,  25,  16, -95, -78; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='Y';  M= -76, -88, -88, -89,  10, -13, -72,   9, -84, -64, -64, -82, -91, -82, -84, -37,   7,  27, -65,  78; D=-38;
/I:         I=-38; DM=-97;
/M: SY='F';  M=  -3, -84, -92, -89,  51, -91, -80,  -4, -85, -61, -63, -85, -92, -87, -86, -75,   7,  36, -70,  49; D=-38;
/I:         I=-38; DM=-97;
/M: SY='M';  M=  21, -71, -64,   6, -62, -69, -63,   1,  10,  11,  70,  31,  39, -58, -62, -59, -56,  22, -78, -63;
/M: SY='V';  M=  49, -68, -71,  -1, -60, -70, -74,  31,   9,  -6, -48, -69, -71, -63, -65, -57, -54,  61, -79, -64;
/I:         I=-9; MD=-22;
/M: SY='Y';  M= -73, -82, -73, -70,  48, -82,  66, -61, -58, -58, -56, -68, -83, -62,  45, -69, -69,  -2, -50,  92; D=-9;
/I:         I=-9; MD=-22;
/M: SY='Y';  M= -69, -82, -72, -65, -55, -82, -63,  -8,  58, -19, -59, -67, -78, -60,  12, -67,   9,  16, -65,  68; D=-9;
/I:         I=-9; MD=-22;
/M: SY='T';  M=   7, -85, -81, -79, -86,  -4, -85, -78, -79, -11, -75, -73,  40, -79, -86,  -2,  54, -74, -97, -86; D=-9;
/I:         I=-9; MD=-22;
/M: SY='G';  M=   8, -87, -77,  -4, -86,  42, -83, -72, -81, -17, -75,  20, -87, -78, -86, -69, -75,  17, -96, -86; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='T';  M=   7, -86, -76,   3, -79,  28, -79, -82, -78, -20, -77, -72, -83, -74, -83,   7,  31, -78, -87,  21; D=-9;
/I:         I=-9; DM=-22;
/M: SY='L';  M=  28, -71, -77, -70, -54, -74, -70, -42,   7,  50, -45, -73, -79, -67, -68,   1, -58,  36, -74,  19; D=-9;
/I:         I=-9; DM=-22;
/M: SY='I';  M= -61, -72,  33, -65, -54, -81, -73,  62, -69,  28, -42, -65, -74,  11, -72, -64,  16,  44, -80, -59;
/M: SY='Q';  M=  31, -73,  32,  29,   7,   5, -60, -61,   1, -66, -62,  12, -68,  56, -56, -52, -57,  22, -77, -63;
/M: SY='K';  M= -61, -75,  18, -45, -74, -68, -56, -66,  76, -23, -61,  39, -67,  43,  10, -54,  10,  -4, -79, -65;
/M: SY='V';  M= -58, -68, -74, -72,  17, -77, -67,  19, -69,  26, -44, -67, -74, -69, -71,   4,  46,  50, -66,  47;
/M: SY='N';  M=  26, -70,  52,   3, -76,  -9, -56, -68,   7, -72,   8,  65, -67, -52, -58,  18, -15,  -8, -86, -69;
/M: SY='Q';  M= -59, -74,  46,   3, -74, -68, -56, -61,   2, -11, -59,  17, -66,  81, -52, -50,  46,   4, -82, -64;
/M: SY='W';  M=  -4, -79, -70,   4,   5, -75,  42,  -1, -55,  19, -52, -68,  12,  17,  39, -65, -64,  -1, 101, -49;
/M: SY='F';  M= -68, -71, -81, -77,  72, -83, -63,   7, -74,  56,  28, -76, -81, -73, -73, -71,   3, -44, -54,  49;
/I:         I=-33; MD=-84;
/M: SY='K';  M= -59, -78, -65, -63, -83,  23, -69, -76,  54, -81, -74,  12, -74, -58, -56,  51,  -2,  -4, -87, -76; D=-33;
/I:         I=-33; MD=-84;
/M: SY='N';  M=   0, -77,  40, -62, -77,  -2, -67, -72,  -2,   5, -68,  50, -76, -65, -69, -56,  44, -70, -93, -75; D=-33;
/I:         I=-33; MD=-84;
/M: SY='C';  M= -76,  41, -99, -93,  19, -99, -89,  18, -91,  26,  32, -92, -95, -90, -91, -86, -73,  38, -88, -67; D=-33;
/I:         I=-33; MI=-84; MD=-84; IM=-84; DM=-84;
/M: SY='G';  M=  19, -82, -82, -83,  30,  40, -77,  -9, -81,   5, -65, -73, -84, -78, -83,   2, -71, -66, -74,  19; D=-33;
/I:         I=-33; DM=-84;
/M: SY='T';  M=  -3, -77, -17, -70, -73,  21, -71, -20, -70, -75, -70,  -7,  18, -68, -76,  33,  46, -15, -83,  18; D=-33;
/I:         I=-33; DM=-84;
/M: SY='T';  M=  24,  36, -67, -66, -64, -64, -71,  50, -65, -55, -54, -57, -67, -62, -70,  52,  54,   4, -81, -65;
/M: SY='C';  M= -22,  81, -69,  18,  19, -78, -75, -39, -67, -11, -51, -68, -75, -69, -72, -59,  35,  65, -81, -60;
/M: SY='V';  M= -58,  42, -74, -63,  29, -79, -69,   6,   2, -48, -48, -68, -76,  59, -62, -63, -56,  72, -71,  13;
/M: SY='R';  M= -59, -76,  37,  21, -76, -67, -58,  -5, -45, -72, -66,  13,  45, -50,  58,  29,  30, -66, -83, -68;
/M: SY='K';  M=  30, -73, -57, -47, -77,  -6, -58, -71,  82, -70,  36,  17, -65,  39, -37, -52, -57, -67, -74, -66;
/M: SY='I';  M= -61, -74,   5,  -9, -54,  19, -69,  49, -69,  44,  32, -67, -74,  14, -71, -66, -60,  19, -76, -59;
/M: SY='K';  M=  -7, -70,   7, -51, -73, -64, -62, -61,  67, -68, -63, -50, -66, -49,   5,  51,  17,  23, -80, -65;
/M: SY='P';  M=  -9,  36, -61,  12, -67, -69,  43,   3,  -4,  20, -55,  11,  67, -56,   4,   3, -57, -60, -80, -65;
/M: SY='C';  M= -64, 101, -86, -81,  57, -81, -81,  26, -76, -13, -52, -76, -83, -80, -79, -71, -63,  35,  95, -46;
/M: SY='F';  M= -67, -71, -85, -80,  88, -84, -69,   6, -77,  36, -42, -78, -83, -79, -75, -73, -62,  38, -54,  25;
/M: SY='D';  M= -28, -76,  49,  19, -74, -68, -58,  24,  11, -67, -62,  41,  17,  18,  24, -53,  30, -60, -83, -67;
/M: SY='W';  M=  49,  36, -73, -65, -58, -65, -74, -60, -64,  15, -56, -66, -71,  16, -68, -53,  46, -58, 117, -53;
/I:         I=-36; MD=-90;
/M: SY='C';  M=   0,  93, -85, -83,  18,  -4, -82,  -5, -80, -20,  29, -75, -86, -82, -84, -68,   3,  22, -86, -68; D=-36;
/I:         I=-36; MD=-90;
/M: SY='E';  M= -67, -78, -69,  36,   4, -86, -72, -51, -68,  25,  30, -72, -77,  22, -71, -66,  34,  27, -83, -65; D=-36;
/I:         I=-36; MD=-90;
/M: SY='A';  M=  42, -81,  38,  19, -88, -71,  31, -85,   4, -84, -78, -61, -75, -62, -68,  -1,  12, -76, -95, -77; D=-36;
/I:         I=-36; MI=-90; MD=-90; IM=-90; DM=-90;
/M: SY='K';  M=  29, -76, -69, -61,  12, -71, -71, -33,  49, -73, -69, -61, -73,  17, -56,   9,  44, -66, -81, -67; D=-36;
/I:         I=-36; DM=-90;
/M: SY='F';  M=   2, -69, -73, -71,  72, -71, -60, -50, -68,  21,  38, -65, -75, -67, -69,  25,  32, -52, -55,  50;
/M: SY='K';  M=  38, -70, -59,  -1, -67, -62, -59, -66,  64, -69, -62, -54, -66, -48,  13,  40, -52,  -3, -71,  25;
/M: SY='A';  M=  63, -69,  26,  -5, -71, -58, -64,   3, -58,  -7, -59, -57,  12, -56,   7,  33, -52, -55, -79, -68;
/M: SY='G';  M=  49, -70,  33, -58, -78,  51, -67, -73, -62, -75, -68, -53,  40, -62, -70, -46,  45, -65, -80, -73;
/M: SY='F';  M=  36, -69, -65,  -8,  38,  -1, -64, -21,  26, -59, -57, -59, -69, -59, -59,  24,   5,  23, -66,  24;
/M: SY='G';  M=   1, -74, -55,  37,  15,  51, -58, -67,   0, -68, -64,  30, -69, -55, -61,  -2, -58,  -4, -65,  46;
/I:         I=-16; MD=-40;
/M: SY='W';  M=  -7, -86, -94, -86,  78, -84, -76, -61, -81, -59, -64, -87, -89, -83, -81, -78, -76,  -7, 114,  52; D=-16;
/I:         I=-16; MD=-40;
/M: SY='W';  M= -94,-102,-110,-101,   7,-110, -98,  24, -91,  28, -66,-104,-106, -94,   5,-100, -91, -68,  66, -71; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='D';  M= -78, -92,  98, -48, -91, -78, -69,  13, -69, -84, -83, -52,  18, -68, -77, -69, -68, -77,-106, -80; D=-16;
/I:         I=-16; DM=-40;
/M: SY='M';  M=  27, -81, -79,  -2,   6, -17, -71, -62,   0,  20,  60, -77, -83, -69, -72, -70, -71, -63, -75,  25; D=-16;
/I:         I=-16; DM=-40;
/M: SY='W';  M=  13, -86, -97, -87,  65, -84, -91, -58, -84, -62, -67, -90, -90, -86, -85, -78, -76,  28, 116, -45; D=-16;
/I:         I=-16; DM=-40;
/M: SY='E';  M= -70, -87,  12,  66, -79, -15, -65, -80,   4, -81, -77,  11, -74, -56, -65, -65,   2, -10, -84,  23; D=-16;
/I:         I=-16; DM=-40;
/M: SY='L';  M=   9, -71,   9,  -1,  11,  -3, -70,  36, -69,  46, -43, -66, -73, -66, -72, -62,  10,   8, -74, -57;
/M: SY='F';  M= -66,  49, -83, -79,  54, -84, -68,  29, -76,  54, -39, -78, -83, -75, -75, -72, -62,  18, -60,  41;
/I:         I=-5; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='K';  M= -69, -80, -70, -60,  41, -79, -60, -61,  65,  -9, -58, -64,   9, -56,  29, -67, -64,  -4, -61,  53; D=-5;
/I:         I=-5; DM=-12;
/M: SY='Q';  M=  -3, -75, -72, -65,  47, -73,  42,  38, -66, -54, -54, -63, -75,  49, -67,  34, -57,  22, -73, -51; D=-5;
/I:         I=-5; DM=-12;
/M: SY='L';  M= -67, -74,   7, -73,  34, -86, -74,  18,  -4,  55, -42, -76, -82, -73, -72, -74, -63,  38, -74, -54; D=-5;
/I:         I=-5; DM=-12;
/M: SY='L';  M= -62, -73, -80, -77,  17,  -6, -73,  33, -75,  43,  37, -71, -78, -71, -76,  18,   4,  18, -75, -57; D=-5;
/I:         I=-5; DM=-12;
/M: SY='H';  M= -61, -75, -56,   0, -74,  30,  68, -74,   6, -18, -64,  45, -70, -56,   0, -52,  53, -71, -87, -65; D=-5;
/I:         I=-5; DM=-12;
/M: SY='G';  M=  -1,  27, -60, -61, -77,  65, -64, -73,  43, -76, -67,  31, -69, -56,   6,  -1, -58,  -3, -78, -71;
/M: SY='L';  M=  29, -70, -77, -69, -13, -75, -68,  28, -69,  44, -41, -73, -77,  22, -70, -63, -58,  43, -69,  26;
/M: SY='Y';  M= -69,  26,   5, -65,  76, -74, -55, -60, -10, -55, -57,  11, -78,  13, -63, -62,   9, -63,  65,  79;
/M: SY='V';  M=   2,  42,  30,  -7, -61, -72, -69,  27, -65,   9, -50,  15, -72, -65, -70, -57,  33,  45, -85, -64;
/M: SY='V';  M= -58, -72, -78, -77, -46,  18, -66,  30, -72,  -9,  53, -72, -77, -70, -73, -65, -58,  66, -64,  63;
/M: SY='V';  M=   3, -67, -75, -71, -55, -74, -77,  18, -69,   7, -46, -68, -73, -69, -73,  -1,  45,  67,  59, -59;
/M: SY='N';  M= -56, -74,  37,  13, -77,  27, -57,  -2,  41, -75, -67,  46, -66,  18, -51,  39, -53, -69, -81, -68;
/M: SY='G';  M=  -7,  41, -61, -65,   7,  70, -65, -72,   2, -73, -67,  32, -70,  12, -64,  10, -58,  -9, -75, -67;
/M: SY='C';  M= -56,  67,  17, -57, -77,  54, -62, -68,   6, -72, -65,  40, -72,  56, -60, -53, -59,  16, -82, -71;
/M: SY='I';  M= -62, -72, -79, -75,  59, -81, -72,  63,  -3, -23, -44, -71, -77, -71, -70,   2, -57,  45, -62,  27;
/M: SY='Q';  M= -58, -72, -61, -56, -61, -71, -59, -45,  19, -57, -53,  39, -72,  61,   7, -55,  16,  60, -74,  30;
/M: SY='F';  M=  -4, -68, -80, -75,  79, -77, -73,  10, -73,  -7, -47, -71, -78, -75, -74,   1,  -2,  58, -63, -41;
/M: SY='V';  M=  14,  27, -78, -72, -57, -36, -79,  -3,  -3,   4, -45, -73, -77, -71, -70, -62, -53,  83, -83, -63;
/M: SY='C';  M=  29,  57, -62, -57, -74,  -6, -62, -68,  11, -70, -63,   8, -70,  18,  52,  19,  21,  -6, -80, -68;
/I:         I=-4; MD=-11;
/M: SY='D';  M=  -6, -87,  74,   8, -93, -13, -67, -92,  20, -90, -85, -55, -76, -60,  10,  -2, -67, -86, -97, -80; D=-4;
/I:         I=-4; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='N';  M= -62, -75, -18,  23, -65, -67,  38, -69,  24,   6, -58,  57, -70,  17,  47,   5, -57, -69, -75,  19;
/M: SY='I';  M= -61, -71, -80, -77,  55, -79, -73,  56, -75,  39, -40, -72, -78, -72, -75,  24, -56,  27, -66, -47;
/M: SY='P';  M= -57, -75, -56, -49, -79, -62, -58, -75,  59, -78, -67,  19,  64,  19,  13,  49,  -2, -72, -78, -69;
/M: SY='R';  M= -61, -78,  31,  45, -77, -71, -56, -14,  43, -73, -66, -51, -65,  20,  64,   5,   0, -69, -79, -66;
/M: SY='W';  M= -63,  62, -74, -71, -46, -11, -64,   6,   3,  45, -46,   1, -79, -66, -67, -10, -60,   2,  63,  52;
/M: SY='V';  M=  20,  43, -77, -74, -47,  -8, -67, -37, -72,  28, -45, -73, -79, -70, -73, -62, -57,  62, -66,  58;
/M: SY='K';  M=  -7, -73, -53, -49, -76,  -3,  39, -70,  68, -73, -63,  50, -67,  44, -41,  10, -54,  -3, -79, -64;
/M: SY='Q';  M=  27,  30, -61, -54, -69, -65, -61,  33,  38, -14, -55,  24, -69,  60, -52,   6,  -2, -53, -77, -64;
/M: SY='F';  M= -66, -69, -85, -79,  81, -85, -71, -34, -78,  58, -38, -80, -84, -78, -76, -74, -62,  39, -59, -38;
/M: SY='C';  M=  20,  79, -81, -75,   4, -76, -72, -17, -74,  53,  32, -75, -80, -72, -75, -65, -59,  33, -76, -58;
/M: SY='D';  M= -64, -79,  93,  31, -84, -22,  33, -84,  -4, -81, -74,  38, -66,  29, -55, -54, -58, -81, -93, -67;
/M: SY='V';  M=  34, -68, -72, -65, -58, -71, -70,  28,  29,  23,  32, -65, -71, -62, -61, -57,  25,  37, -77, -61;
/M: SY='Y';  M=   8, -70, -80, -75,  60, -77, -61, -39, -72,  31,  37, -75, -80, -71, -71, -67, -60,  38, -53,  67;
/M: SY='N';  M= -59, -70, -47, -55, -69, -59, -50, -73,  14, -75, -65,  88, -70, -12,  42,  27,  33, -70, -79,  18;
/M: SY='K';  M=   6, -69, -56, -52, -74,   0, -61, -69,  71, -73, -65,  12, -63, -50, -44,  30,  54, -33, -79, -67;
/M: SY='F';  M=  41, -71,  25, -67,  82,   1, -66,   5, -70, -52, -55, -64, -76, -71, -72, -59, -60,  -6, -56,  24;
/M: SY='M';  M=  -1, -70, -83, -76,  43, -79, -66,  37, -74,  52,  88, -76, -77, -69, -72, -70, -61, -38, -66, -47;
/M: SY='K';  M= -14, -76,  13,  61, -81, -66, -56, -79,  67, -76, -68, -49, -61,  43, -40,  27, -55, -73, -77, -68;
/M: SY='M';  M= -59, -68, -75, -70, -52, -79, -70,  22,   4,  42,  57, -68, -73, -66, -66, -61,  48,  43, -78, -58;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 53 in 53 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CoV Nsp2 middle
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

R1AB_BC133  (P0C6W1), R1AB_BC279  (P0C6V9), R1AB_BC512  (P0C6W0), 
R1AB_BCHK3  (P0C6W2), R1AB_BCHK4  (P0C6W3), R1AB_BCHK5  (P0C6W4), 
R1AB_BCHK9  (P0C6W5), R1AB_BCRP3  (P0C6W6), R1AB_CVBEN  (P0C6W7), 
R1AB_CVBLU  (P0C6W8), R1AB_CVBM   (P0C6W9), R1AB_CVBQ   (P0C6X0), 
R1AB_CVH22  (P0C6X1), R1AB_CVHN1  (P0C6X2), R1AB_CVHN2  (P0C6X3), 
R1AB_CVHN5  (P0C6X4), R1AB_CVHNL  (P0C6X5), R1AB_CVHOC  (P0C6X6), 
R1AB_CVM2   (P0C6X8), R1AB_CVMA5  (P0C6X9), R1AB_CVMJH  (P0C6Y0), 
R1AB_CVPPU  (P0C6Y5), R1AB_FIPV   (Q98VG9), R1AB_MERS1  (K9N7C7), 
R1AB_PEDV7  (P0C6Y4), R1AB_SARS   (P0C6X7), R1AB_SARS2  (P0DTD1), 
R1A_BC133   (P0C6F7), R1A_BC279   (P0C6F5), R1A_BC512   (P0C6F6), 
R1A_BCHK3   (P0C6F8), R1A_BCHK4   (P0C6T4), R1A_BCHK5   (P0C6T5), 
R1A_BCHK9   (P0C6T6), R1A_BCRP3   (P0C6T7), R1A_CVBEN   (P0C6T8), 
R1A_CVBLU   (P0C6T9), R1A_CVBM(P0C6U0), R1A_CVBQ(P0C6U1), 
R1A_CVH22   (P0C6U2), R1A_CVHN1   (P0C6U3), R1A_CVHN2   (P0C6U4), 
R1A_CVHN5   (P0C6U5), R1A_CVHNL   (P0C6U6), R1A_CVHOC   (P0C6U7), 
R1A_CVM2(P0C6U9), R1A_CVMA5   (P0C6V0), R1A_CVMJH   (P0C6V1), 
R1A_CVPPU   (P0C6V2), R1A_MERS1   (K9N638), R1A_PEDV7   (P0C6V6), 
R1A_SARS(P0C6U8), R1A_SARS2   (P0DTC1)
» more

PDB
[Detailed view]
3 PDB

7FAC; 7MSW; 7MSX