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PROSITE entry PS51991


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General information about the entry

Entry name [info] COV_NSP2_C
Accession [info] PS51991
Entry type [info] MATRIX
Date [info] 25-MAY-2022 CREATED;
25-MAY-2022 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51989
Associated ProRule [info] PRU01335

Name and characterization of the entry

Description [info] Coronavirus (CoV) Nsp2 C-terminal domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=127;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=122;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6047168; R2=0.0077376; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=956; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=504; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-40; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='H';  M= -13, -73, -70, -64, -55, -75,  71,  11, -56,  51, -43, -63, -76, -57,  48,   8, -59,  -4, -78, -54;
/M: SY='D';  M= -61, -73,  68,  28, -78, -66, -55, -76,  28, -76, -70,  45, -64, -48,  20, -49,  53, -71, -88, -68;
/M: SY='T';  M= -57, -70,  28, -49, -75, -64, -56, -71,  -4, -73, -65,  42, -66,  42,  44,  24,  67, -66, -84, -66;
/M: SY='V';  M= -57, -70, -84, -79, -51, -86, -85,  65, -76,  -5, -39, -78, -77, -76, -78, -69, -54,  84, -82, -59;
/M: SY='C';  M= -55,  92, -59,  19, -68, -68, -67,  12,   2, -62, -60,  24, -71, -59, -64,  34,  35,  20, -87, -69;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='W';  M= -66, -78, -86, -79, -46, -83, -83,  73, -75,  34, -41, -79, -76, -73, -78, -72,   5,   2, 115, -48;
/M: SY='A';  M=  78, -65, -67, -64, -75,  43, -70, -63, -64, -68, -63, -58, -67, -61, -69,  15, -53,   6, -77, -71;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='C';  M=  20,  54, -65, -66, -63, -65, -68,  19, -63,  -9, -54,  24, -71, -62, -22,  43,  25,  35, -83, -65;
/M: SY='K';  M=  -9,  38, -57, -48, -78, -66, -61, -75,  88, -76, -66,   5,  34, -47, -36,  -1,   9, -70, -77, -69;
/M: SY='F';  M= -67, -71, -86, -81,  81, -85, -73,  45, -78,  42, -39, -79, -82, -79, -77, -74, -62,  29, -59, -38;
/M: SY='Y';  M= -59, -76,   9, -52, -54, -66, -51, -72,  60, -70, -63, -53,   0, -48,  30,  46, -54, -70, -58,  77;
/M: SY='Y';  M=  45, -68, -53,  39, -58, -61, -55, -66, -56, -67, -62,  24, -65, -53, -61,  14,  50, -60, -65,  62;
/M: SY='Y';  M= -62,  35, -81, -77,  32, -83, -66,  11, -74,  34, -41, -77, -82, -73, -74, -70, -59,  60, -60,  65;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='N';  M=  41, -74, -59,   5, -84,   5, -67, -78, -64, -81, -74,  59, -73, -63, -71,  -6,  42, -71, -91, -79; D=-8;
/I:         I=-8; DM=-20;
/M: SY='G';  M= -67, -80, -80, -79,  12,  40, -78, -58, -78,  35, -57, -72,  32, -78, -82, -66,  26,  -4, -80, -67; D=-8;
/I:         I=-8; DM=-20;
/M: SY='R';  M= -64,  34,   9, -68, -81,  29, -70,   6, -60, -77, -72,  14, -78, -65,  40,  18,  29, -70, -90, -76; D=-8;
/I:         I=-8; DM=-20;
/M: SY='E';  M= -67, -84,  -4,  59, -74, -80, -66, -64,   3, -73, -70,   9,  24, -57, -65, -11, -63,  32, -83,  20; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M=  -4, -81, -73, -70, -74,   3, -74, -66, -71, -75, -70, -68,  68, -71, -78,  27,  25,  14, -82,  20; D=-8;
/I:         I=-8; DM=-20;
/M: SY='F';  M= -79, -82, -85, -79,  79, -88, -65, -58,  20,  19, -55, -80, -89, -76, -69, -78, -73, -63, -52,  67; D=-8;
/I:         I=-8; DM=-20;
/M: SY='I';  M= -70, -81, -93, -90,  12, -96, -91,  75, -86,  -3, -46, -86, -85, -85, -88, -80, -65,  47, -81, -61; D=-8;
/I:         I=-8; DM=-20;
/M: SY='V';  M=  12, -76,  -5,  -4,  45, -79, -78, -50, -75,  -3, -59, -73, -81, -74, -78,  -1,  -1,  46, -79, -59; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M= -72, -87, -74, -67, -72, -81,  26,  39, -65, -15,  51,  16,  53,  41,   5, -70, -68, -58, -86, -68; D=-8;
/I:         I=-8; DM=-20;
/M: SY='S';  M= -54,  48, -57,  15, -79,  -7, -63, -80,  21, -80, -73,  13, -70, -52,   9,  69,   5, -73, -86, -72; D=-8;
/I:         I=-8; DM=-20;
/M: SY='G';  M= -61, -81,  46, -57, -85,  65, -63, -89,  28, -86, -77,  25, -72, -58,  31, -56, -65, -84, -83, -75; D=-8;
/I:         I=-8; DM=-20;
/M: SY='C';  M=  31,  62, -73, -75,  10,  47, -77,   1, -72, -66, -64, -62, -74, -72, -77, -54,  39,  -3, -80, -68; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Y';  M= -73, -81, -88, -85,  12, -92, -69,  20, -82,  46, -45, -86, -90, -78, -80, -80, -69,  23, -62,  71; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Y';  M= -73,  39, -76, -77,  19, -82,  59, -66, -74,  -2, -58, -70, -86, -70, -72,  -1,   4, -68, -56,  91; D=-8;
/I:         I=-8; DM=-20;
/M: SY='C';  M= -66,  75, -66,   2, -82, -76,  47, -86,   5, -81, -73, -60, -78, -57,  55,  33,   3, -78, -92, -71; D=-8;
/I:         I=-8; DM=-20;
/M: SY='V';  M= -61, -77, -80, -71, -67, -83, -79, -39,  -7,  -7, -54, -74, -82,  40, -70,  11, -59,  74, -90, -69; D=-8;
/I:         I=-8; DM=-20;
/M: SY='C';  M= -62,  77, -69,   3, -76, -76, -74,  21,  -4, -69, -67, -63, -77,  19, -69,  42,  24, -14, -91, -75; D=-8;
/I:         I=-8; DM=-20;
/M: SY='T';  M= -66, -80, -64,  19, -74, -79, -68,  20, -57, -14, -62,  15, -75,  32,  30,  -3,  39,  -9, -88, -71; D=-8;
/I:         I=-8; DM=-20;
/M: SY='K';  M= -66,  38, -70, -58, -65, -80, -64, -57,  51,  15, -55, -64, -78,  36,  46, -65, -63,  23, -76,  10; D=-8;
/I:         I=-8; DM=-20;
/M: SY='G';  M=  30, -76, -66,   2,  32,  47, -69, -75, -65, -73, -68, -61,  28,  28, -70,  -3,   7, -70, -74, -64; D=-8;
/I:         I=-8; DM=-20;
/M: SY='K';  M=  13, -79, -60,  25, -77, -73, -62, -74,  75,  -5, -64, -58, -70, -47,  43, -60, -63, -71, -78, -69; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='D';  M= -67,  37,  45,  38, -85, -26, -68,  -3,  -1, -81, -77, -59, -75, -57,  20,  32, -63, -75, -93, -77; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Q';  M= -68, -83,   5,  25, -73, -85, -71, -52, -65,  15, -57, -71, -80,  69, -67, -69, -67,  47, -88, -71; D=-8;
/I:         I=-8; DM=-20;
/M: SY='M';  M= -70, -80, -81, -77,  28,  -8, -69, -57, -75,  34,  37, -74, -16,   5, -76,  -7,  27, -61, -71,  35; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Q';  M=  -1, -84,  35, -56,  37, -13, -64, -75, -63, -16, -67,  17, -80,  77, -65, -62, -69, -76, -79, -62; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='L';  M= -83, -88, -99, -94, -56,-102, -83,  23, -93,  57, -49, -97, -98, -87, -91, -91, -78, -11, -80,  30; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M= -77, -88, -93, -87, -70, -96, -91,   7, -88,  32, -58, -90,  37, -87, -91, -81,  16,  30, -95, -78; D=-8;
/I:         I=-8; DM=-20;
/M: SY='M';  M= -76, -84, -94, -88, -68, -94, -79, -10, -84,   9, 100, -84, -88, -79, -85, -79,  28,  -6, -93, -71; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M= -78,-103, -74,  -1, -99, -81, -79, -87, -71, -95, -82, -82, 108,  13, -82, -74, -72, -91, -91, -93; D=-8;
/I:         I=-8; DM=-20;
/M: SY='H';  M= -12, -84,   3, -74, -76,  27,  35, -67,  -2,  18, -65, -68, -84, -72, -75,  11, -69,   2, -92, -74; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='D';  M= -73, -93,  59,  -5, -97,  22, -68, -96,  27, -92, -83, -57, -78,  53, -11, -66, -73, -92, -94, -81; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='Q';  M=  36, -85, -76, -71, -87, -75, -77,  21, -72, -77, -72,  16, -84,  50, -76,  11, -14, -67, -94, -81; D=-8;
/I:         I=-8; DM=-20;
/M: SY='K';  M= -74,  47, -65,  32, -91, -82, -73, -90,  69, -89, -80, -67,  52, -57, -51, -70, -70, -86, -89, -83; D=-8;
/I:         I=-8; DM=-20;
/M: SY='K';  M= -69, -86, -67, -55, -88, -76, -66, -83,  70, -81,  31, -10, -76,  58, -46,  21, -65, -81, -86, -74; D=-8;
/I:         I=-8; DM=-20;
/M: SY='E';  M=   9, -75, -52,  64,  63, -71, -58, -67,  15, -62, -61, -58, -65,  58, -52, -55,  10, -65, -65, -50;
/M: SY='I';  M=   2, -71, -71, -69, -53, -38, -67,  40,  -4,  32, -45,  10,  17, -65, -67,   2, -55,  35, -72,  22;
/M: SY='T';  M= -54, -70, -59,  27, -61,  28, -64,  29, -60, -60, -57, -55, -65, -58, -67,  19,  68,  -4, -73,  31;
/M: SY='F';  M= -70,  48, -85, -82, 101, -83, -67,  23, -77, -12, -48, -76, -84, -82, -76, -72, -64,   0, -48,  39;
/M: SY='L';  M= -67, -71, -71,   3,  36, -81, -64, -41, -10,  74, -37,   9, -79, -63,   2, -70, -62, -47, -68, -50;
/M: SY='D';  M= -60, -76,  63,  61, -78, -68,  32, -71,  15, -73, -68,  13, -63,  11, -53,   4,  -3,   2, -87, -66;
/I:         I=-36; MD=-90;
/M: SY='C';  M=  25,  62, -98, -91,-105, -91,-101, -98, -94,-101, -94, -93,  49, -95,-102, -80,   2, -91,-112,-105; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='V';  M= -86, -96, -99,-102,   8,-104, -97, -59, -97, -72,  32,  22,-106, -98, -99, -92, -82,  51,-107, -82; D=-36;
/I:         I=-36; DM=-90;
/M: SY='G';  M= -54, -78, -64, -67,   6,  78,  30, -81, -66, -79, -70, -55,  68, -65, -73,  13, -62, -79, -74, -68;
/M: SY='D';  M= -57, -73,  48,  31, -70, -69, -64,   4, -59, -61, -60,  19,  38, -57, -66,  13,  19,  46, -87, -68;
/M: SY='T';  M=  44, -65, -68, -66,  11,   8, -71,  11, -65, -57, -56, -58, -68, -64, -70,  31,  47,  33, -77, -61;
/M: SY='D';  M= -60, -74,  63,  39, -72, -67,  58, -62,   3, -20, -62,  34, -67, -50, -57,  13, -54,  24, -89, -63;
/M: SY='P';  M=  -6, -77,  61, -49, -81, -61, -61, -75, -58, -80, -72,  12,  87, -58, -67,  38,  11, -72, -86, -74;
/M: SY='T';  M=   2, -69, -64, -64,  23,  12, -68,   5, -11, -59, -57,  15,  15, -63,   2, -50,  64,  22, -76, -60;
/M: SY='V';  M=  -5, -70,  12,  -3, -63, -72,  36,  28, -11, -53, -52, -58, -70, -59,   4,  13,  24,  56, -84, -61;
/M: SY='I';  M= -62, -71, -83, -79,  46, -85, -78,  64, -76,  24, -39, -75, -77, -76, -77, -68,   7,  54, -70, -49;
/M: SY='E';  M=   5, -70,  37,  59, -71, -65, -58, -66, -53,   6, -62,  22, -63, -49, -61,  19,  48, -62, -84, -68;
/M: SY='T';  M=  -2, -67,  62, -52, -71, -64, -64,   2, -59, -65, -63, -47, -64, -59, -66,  35,  75,  -2, -88, -66;
/M: SY='D';  M= -10, -74,  74,  62, -82, -61, -53, -81, -50, -80, -75,  50, -63, -46, -58,  31, -52, -75, -89, -71;
/M: SY='V';  M= -57, -72,  27,  51,   7, -73,  34, -46, -59, -10,  21, -59, -69, -55, -64,  26, -54,  53, -81, -58;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='V';  M= -57, -69, -84, -78, -50, -86, -82,  44, -76,  28, -38, -79, -79, -76, -77, -69, -54,  84, -82, -59;
/M: SY='E';  M= -60, -77,  44,  88, -71, -76, -59, -58, -50,   2, -61, -57, -63, -45, -59, -60, -58,  30, -83, -68;
/M: SY='L';  M= -61, -68, -70,   1, -49, -80, -68, -33, -69,  65, -38,  22, -78, -66, -71, -66,  -4,  52, -78, -59;
/M: SY='V';  M= -57,  38, -59,  49, -64, -78, -68, -42,  49,  -9, -53, -64, -70, -54, -53, -62, -55,  66, -82, -65;
/M: SY='T';  M= -59, -73,  13,  42, -74, -68,  39, -65,  37, -70, -64,  24,  34, -50, -52, -15,  50,   6, -85, -66;
/M: SY='G';  M=  43, -67, -64, -66, -75,  64, -69, -67, -64, -71, -65, -53, -66, -63, -70,  13,  51,  -7, -78, -71;
/M: SY='Q';  M= -56, -75,  44,  53, -77, -67, -58, -64, -51, -70, -65, -51,  25,  55, -58,  37,   4,  19, -83, -68;
/M: SY='L';  M= -69, -71, -84, -78,  65, -84, -64, -38, -77,  74, -35, -81, -85, -73, -74, -75, -64, -45, -55,  43;
/M: SY='E';  M= -54, -71, -51,  66, -69, -73, -64, -50,   0, -60, -58, -58, -64,  15, -57,  11,  43,  52, -83, -67;
/I:         I=-24; MD=-60;
/M: SY='E';  M=   9,-103, -73,  51, -90, -94, -81,-100,  -6, -97, -91, -86,   5, -71, -80, -81, -85, -94, -91,  29; D=-24;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='P';  M= -84,-107, -90, -80,-104, -91, -92, -87, -85, -99, -90, -90,  85,   4, -94,   6, -79, -10,-105,-100; D=-24;
/I:         I=-24; DM=-60;
/M: SY='C';  M= -78,  51, -87, -83,  10, -93, -82, -23, -81, -74, -73, -78, -91,  26, -84, -71,  50,   2, -85,  30; D=-24;
/I:         I=-24; DM=-60;
/M: SY='G';  M= -74, -94,  29,  10,-100,  43, -76,-103, -16,-102, -93,  36, -85, -71, -79,  -8, -75, -98,-102, -92; D=-24;
/I:         I=-24; DM=-60;
/M: SY='Y';  M= -11,  47, -74,  36, -70, -86, -72, -85, -76, -81,  17, -79, -88, -70, -80,  19, -74, -82, -78,  60; D=-24;
/I:         I=-24; DM=-60;
/M: SY='C';  M= -17,  77, -85, -84,  31, -84,  70, -90, -84, -82, -80, -74, -94, -80, -85,  30, -74, -85, -96, -67; D=-24;
/I:         I=-24; DM=-60;
/M: SY='Q';  M= -73, -91,   7,  13, -95,  -5, -79, -86,   8, -89, -84, -68, -82,  28, -72,  10,  25, -16,-100, -86; D=-24;
/I:         I=-24; DM=-60;
/M: SY='P';  M= -77, -98, -74,  -6, -95, -81, -80, -81, -74, -92, -82,  20,  96, -76, -85, -24, -70,  -9, -97, -93; D=-24;
/I:         I=-24; DM=-60;
/M: SY='P';  M= -12, -83,  -1,  22, -83,  16, -65, -77,   2, -82, -71, -61, 102, -57, -65,   5, -57, -76, -79, -78;
/M: SY='K';  M=  28, -72, -65, -57, -69,  19, -65, -60,  56,   3,  36, -58,  38, -56, -52, -20,   1, -13, -75, -66;
/M: SY='V';  M= -55,  40,  -4, -66, -59, -72, -71,  31,   0,   8, -48,   9, -74, -65, -67,  35, -51,  60, -83, -63;
/M: SY='V';  M=   5, -69,  33, -61,  20,  -4, -66, -10,   1, -55, -55,  49, -74, -64, -65, -57, -54,  62, -80, -60;
/M: SY='G';  M= -52, -78,  22,  37, -83,  91, -66, -89, -62, -84, -76, -49, -66, -58, -70, -51, -66, -83, -77, -76;
/M: SY='K';  M= -59, -72,  37, -51, -74,  18, -60,  -1,  62, -71, -65,  41, -65, -52, -48, -49,  55, -64, -82, -68;
/M: SY='I';  M= -65, -78, -77, -70, -46, -81, -66,  61, -69,  27, -42, -74,  52,  18, -72, -68, -60,  17, -63,  58;
/M: SY='C';  M=  16,  95, -81, -76,  12, -77, -81,  22, -74, -47, -50, -73, -80, -77, -77, -63, -55,  70, -82, -62;
/M: SY='C';  M= -60,  77, -82, -79,  13, -82, -80,  74, -76,  -2, -43, -73, -78, -75, -79,  -1, -56,  41, -77, -57;
/M: SY='I';  M= -59, -71, -85, -80, -50, -87, -83,  77, -77,  15, -37, -78, -77, -76, -79, -71, -55,  69, -79, -58;
/M: SY='D';  M=  27, -71,  85, -44, -81, -55, -55, -77, -55, -79, -74,  52, -67, -53, -62,  48, -49, -72, -91, -70;
/M: SY='G';  M= -55, -75,  37,  24, -81,  64, -57, -84,  11, -83, -74,  61, -67, -53, -59,   3, -57, -80, -82, -73;
/M: SY='Y';  M= -65, -74,   8, -60,  11, -77,  37, -48,  47,  36,  44, -62, -75, -58, -53, -66, -61,   9, -62,  59;
/M: SY='Y';  M= -10, -71, -73, -71, -39, -74, -54,  -7, -67,  25,  71, -68, -75, -62, -67,  -2,  23,   1, -54,  86;
/M: SY='F';  M= -69, -70, -86, -79,  94, -82, -64, -41, -75,  36,  89, -76, -81, -75, -72, -74, -64, -47, -53, -32;
/M: SY='Y';  M=  28, -72, -76, -73, -41,   3, -61, -44, -70,  21, -48, -72, -78, -67, -70, -61, -60,  42,  63,  82;
/M: SY='K';  M= -62, -79, -53,  39, -65, -72, -53, -77,  75, -73, -64, -53, -66, -41,  56,  -1, -59, -73, -65,  46;
/M: SY='C';  M=   5,  77,  56, -56, -68, -68, -67,  15,   2, -10, -59, -53, -71, -62, -65,  13,  34,  -2, -87, -67;
/M: SY='G';  M= -56, -77,  28,  52, -79,  62, -63, -72,  40, -75, -69, -51, -65, -51, -55, -54, -61,  11, -79, -72;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='D';  M= -33, -77, 108, -37, -84,  -2, -56, -81, -56, -81, -78,   0, -66, -56, -64, -51,  28, -77, -98, -70;
/M: SY='K';  M= -58, -75,  30,  30, -75,  14, -58, -67,  55, -18, -63,  25, -66,  30, -47, -10,   1,  -4, -80, -67;
/I:         I=-38; MD=-97;
/M: SY='E';  M= -90,-104, -72,  57,  29,-103,  52,  -6, -78, -84, -84, -84, -90, -72, -83, -87, -88, -86, -96, -73; D=-38;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='Y';  M= -73, -77, -77, -78,  88, -80, -47, -53, -71, -47, -50, -74, -85, -71, -68, -69, -66, -58, -32, 111;
/M: SY='Y';  M= -69,  77, -73, -74,  28, -78, -45, -60, -64, -55, -53, -70, -84, -64,   6, -66, -65, -62, -37, 118;
/M: SY='P';  M=  26, -84, -67, -57, -75, -65, -67, -71, -63, -78, -67, -71, 116, -65, -73, -59, -58, -72, -73,  20;
/M: SY='V';  M=  12, -68, -74, -71, -48, -72, -67,  15, -70,  41, -43, -69, -75, -66, -71,  24,   4,  45, -69,  40;
/M: SY='C';  M= -10,  76,  31, -60, -70,  12, -67, -54,   1, -64, -62,  17, -73, -62, -65,  38, -51,  46, -87, -69;
/M: SY='P';  M= -55,  38, -69, -68,   6,  33, -70, -14, -67, -58,  42, -61,  52, -67, -72,  20,  30,  32, -78, -63;
/M: SY='N';  M= -58, -73,  56, -53, -80,  51, -54, -80,   0, -82, -73,  84, -69, -55, -60, -48,   9, -78, -88, -72;
/M: SY='G';  M= -56, -73,  29, -62, -71,  66, -60, -68,  -3,   5,  49,  47, -70, -59, -64,  -1, -59, -68, -79, -68;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='C';  M= -82,  47, -91, -89, -88,  29,  19, -86,  18,   2,  23, -81, -96, -83, -81, -83, -86, -86,-101, -86; D=-36;
/I:         I=-36; DM=-90;
/M: SY='V';  M=  26, -67, -81, -75, -53, -77, -79,  39, -74,  25, -41, -76, -77, -72, -75, -64, -54,  75, -80, -61;
/M: SY='V';  M= -58, -66, -78, -73, -49, -82, -74, -29, -73,  60, -37, -73, -77, -71, -74, -63,  42,  64, -80, -58;
/M: SY='P';  M=  -9, -78,  62, -47, -83,  -3, -57, -78, -55, -81, -71,  51,  73,  38, -63,   6, -54, -77, -86, -73;
/M: SY='Q';  M= -57, -72, -55, -52, -71, -66,  11,  -2,  22, -63, -57,  51, -68,  68,   5,   1,  40,  21, -82, -63;
/M: SY='C';  M=  58,  85, -75, -69, -61, -65, -71, -49, -69,  19,  52, -67, -74, -67, -72, -54,   1,  18, -81, -66;
/M: SY='W';  M= -75, -78, -89, -82, 104, -80, -69, -55, -75, -48, -55, -80, -84, -81, -74, -75, -72, -61, 121,  46;
/M: SY='R';  M= -62, -75, -57, -52, -75, -70, -54, -76,  28, -74, -64,  33, -70, -44,  92, -14,  45, -70, -79, -64;
/M: SY='K';  M= -65, -72, -72, -61,  48, -79, -65, -45,  66,  53, -43, -66, -75, -59, -50, -68, -60,   9, -66, -49;
/M: SY='K';  M=  -6, -78, -63, -51, -73, -69, -61, -66,  76, -14,  51, -59,  70, -50,  11, -60, -58, -66, -74, -66;
/M: SY='C';  M=  19,  95, -68, -75, -79,  83, -73, -83, -70, -78, -71, -55, -73, -70, -77, -51, -64, -73, -80, -78;
/M: SY='G';  M=  44, -72, -65, -71, -81,  91, -71, -83, -68, -80, -71, -53, -68, -65, -74, -47, -63, -73, -74, -76;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 53 in 53 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CoV Nsp2 C-terminal
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

R1AB_BC133  (P0C6W1), R1AB_BC279  (P0C6V9), R1AB_BC512  (P0C6W0), 
R1AB_BCHK3  (P0C6W2), R1AB_BCHK4  (P0C6W3), R1AB_BCHK5  (P0C6W4), 
R1AB_BCHK9  (P0C6W5), R1AB_BCRP3  (P0C6W6), R1AB_CVBEN  (P0C6W7), 
R1AB_CVBLU  (P0C6W8), R1AB_CVBM   (P0C6W9), R1AB_CVBQ   (P0C6X0), 
R1AB_CVH22  (P0C6X1), R1AB_CVHN1  (P0C6X2), R1AB_CVHN2  (P0C6X3), 
R1AB_CVHN5  (P0C6X4), R1AB_CVHNL  (P0C6X5), R1AB_CVHOC  (P0C6X6), 
R1AB_CVM2   (P0C6X8), R1AB_CVMA5  (P0C6X9), R1AB_CVMJH  (P0C6Y0), 
R1AB_CVPPU  (P0C6Y5), R1AB_FIPV   (Q98VG9), R1AB_MERS1  (K9N7C7), 
R1AB_PEDV7  (P0C6Y4), R1AB_SARS   (P0C6X7), R1AB_SARS2  (P0DTD1), 
R1A_BC133   (P0C6F7), R1A_BC279   (P0C6F5), R1A_BC512   (P0C6F6), 
R1A_BCHK3   (P0C6F8), R1A_BCHK4   (P0C6T4), R1A_BCHK5   (P0C6T5), 
R1A_BCHK9   (P0C6T6), R1A_BCRP3   (P0C6T7), R1A_CVBEN   (P0C6T8), 
R1A_CVBLU   (P0C6T9), R1A_CVBM(P0C6U0), R1A_CVBQ(P0C6U1), 
R1A_CVH22   (P0C6U2), R1A_CVHN1   (P0C6U3), R1A_CVHN2   (P0C6U4), 
R1A_CVHN5   (P0C6U5), R1A_CVHNL   (P0C6U6), R1A_CVHOC   (P0C6U7), 
R1A_CVM2(P0C6U9), R1A_CVMA5   (P0C6V0), R1A_CVMJH   (P0C6V1), 
R1A_CVPPU   (P0C6V2), R1A_MERS1   (K9N638), R1A_PEDV7   (P0C6V6), 
R1A_SARS(P0C6U8), R1A_SARS2   (P0DTC1)
» more

PDB
[Detailed view]
3 PDB

7FAC; 7MSW; 7MSX