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PROSITE entry PS52013


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General information about the entry

Entry name [info] ZF_C6H2
Accession [info] PS52013
Entry type [info] MATRIX
Date [info] 03-MAY-2023 CREATED;
03-MAY-2023 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52013
Associated ProRule [info] PRU01357

Name and characterization of the entry

Description [info] Zinc finger C6H2-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=56;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=51;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6833065; R2=0.0077849; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1968; N_SCORE=18.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=491; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-54; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='M';  M=  -7,-120, -42,  20,-118,  19,-110,   0,  14, -79,  51, -36,  11,  17,-107,  44,  14, -18,-126, -45;
/M: SY='H';  M=  -8,-122, -36, -48, -72, -25,  55,  13,   0, -38,  10,  30,   3,  23,  47, -24, -13,  11, -20, -25;
/M: SY='P';  M=   5,-119,-114, -65, -21, -83,  23,  27,  23, -10,  17, -56,  35, -12, -32,   5,  33,  26,-124, -37;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='S';  M=  32,  21, -12,  27, -59,-109, -23, -39, -63, -31, -35,   2, -59,  47,-108,  54,  -8, -11,  49,-110;
/M: SY='G';  M=   3,-118, -35,-112, -48,  72,-112,-120, -40, -45,-114,  18,-115,-106,   9,  36,  32, -44,-125,-117;
/I:         I=-29; MD=-75;
/M: SY='P';  M=  -8, -28, -23,  -1, -54, -48, -47, -40, -75, -23,-132, -44,  63,-131,-140, -24, -52, -78,-151,-141; D=-29;
/I:         I=-29; MD=-75;
/M: SY='G';  M= -63,-149,  -3,   5, -55,  32,-132,-154, -74,-153,-145,  20, -30,  15, -74,   6,-130,-151,-153,-143; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/I:         I=-28; MD=-70;
/M: SY='G';  M= -37,-142, -46,-133,-147,  68,-134, -80, -17, -92,-138, -16,  -1,-128,-134,   1, -57,-142,-144,-141; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='K';  M= -76,-141, -69, -12,-141,  12, -19, -56,  59, -67,-129,  12,-132,  -6, -32, -46, -59, -25,-143,-132; D=-28;
/I:         I=-28; DM=-70;
/M: SY='N';  M=  -3,-122,  11,  38,-124,   6, -41, -75,  21, -78,-113,  50,  43,  34,-103,   3, -32,  -2,-128, -52;
/M: SY='T';  M=  36, -31,  -2,   6,-119, -34, -19, -58,  33, -25,-108,  19,  16, -41,-104, -24,  57,  -2,-129,-115;
/M: SY='P';  M=  39, -42,  -4,  15, -36, -56,-111, -78, -11, -51,-111,  16,  63, -17,-110,  14,  46, -33,-128,-116;
/M: SY='S';  M=  52, -36, -51, -50, -35,  18,-110,-116,  -6,-117,  -1, -36, -58, -48,   8,  67,  -6, -33,-125,-114;
/I:         I=-29; MD=-75;
/M: SY='K';  M= -44,-120, -37, -28, -15,-114, -11, -71,  62, -38,-109,  33,-114,  26,  30,  21,  48, -46,-126,-110; D=-29;
/I:         I=-29; MD=-75;
/M: SY='L';  M=-119, -26,-132,-127,  23, -68,-117, -45, -69,  77,  57,  -9,-134,-121,-124, -72,-114, -96,-120, -29; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='Q';  M=  -9,  27,-106,  10, -45,-117, -53,-124,  46,-122,-113, -42,-117,  90,  16,  13, -16, -57,-127,-115; D=-29;
/I:         I=-29; DM=-75;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='P';  M=-114,-139,-114,-102,-133,-116,-116,-122, -33,-131,-118,-119, 132, -22,-119,-111,-107,-126,-126,-130;
/M: SY='T';  M= -70,-116,-111,-107,-110,-120, -16,  22,  51,   5, -98, -12,-115, -20, -32, -31,  74,  30,-128,-109;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='L';  M= -74,-120, -63, -60, -45,-125,   0,  40,  33,  41,   4, -13,-121,  33, -37, -69,   1,  34,-124,-105;
/M: SY='K';  M= -11, -39,  16,  34,-127, -76,-104, -60,  87,-123,-114,  13,-111,  26, -38,  -2, -32,-119,-125,-115;
/M: SY='L';  M= -16,-120, -34,  -9,  -9,-124, -18,   9,  -4,  67,  14,  -9,-123,  36, -20, -68, -67, -95,-118, -15;
/M: SY='G';  M= -36,-122,  18,  -5,-127,  71,-107,-128,  40, -85,-118,  52, -63,  -8, -55,  -1,-105, -66,-126,-119;
/M: SY='I';  M= -31,-120, -51,-117, -38, -78, -27,  66,   1,  58, -86, -23,-124, -26,   5,-116, -59,  -7,-121,-104;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='P';  M=  -4, -25,  12,   9,-148, -73, -37,-141,  -5, -89,-136, -60,  57, -34, -25, -21, -19, -82,-150,-140; D=-20;
/I:         I=-20; DM=-51;
/M: SY='P';  M= -19,-124,  16, -17,-121,  23,  10,   9,   9, -86,-111,  -4,  50, -50, -35,  15,   2,  16,-130, -53; D=-20;
/I:         I=-20; DM=-51;
/M: SY='S';  M=  33, -39,-108, -52,-123, -27,-111, -19, -39,-121,-115, -15,-115, -13, -53,  92, -31, -63,-130,-117; D=-20;
/I:         I=-20; DM=-51;
/M: SY='Y';  M= -26,  -7,-125,-122,  81,-126,  10, -10,-117, -28,-100, -53, -25, -50, -21, -22, -63,  -6,  -9,  85; D=-20;
/I:         I=-20; DM=-51;
/M: SY='F';  M=-125,-122,-136,-132, 124,-132,-113, -99,-127, -91,-100,-126,-135,-136,-124,-123,-117,-104, -89,  40; D=-20;
/I:         I=-20; DM=-51;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='S';  M= -41,   6,  17,-105,-123,  25,-108,-121,-106,-124,-117,  10,-112,-101,-112,  90,  45,-114,-132,-116;
/M: SY='Q';  M= -70,-131,-101, -16,-135,-115, -97,-122, -28,-119,-106, -26,  -7, 132, -30, -51,-108, -59,-121,-110;
/M: SY='E';  M=  13,-122,  68,  70,-126, -36,-105,-118, -21, -58,-115, -26, -55,  16,-105, -20,  16, -14,-132,-117;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='C';  M=-109, 159,-128,-128,-119,-124, -18,-126,-124,-116,-116,-114,-139,-131,-130,-111,-109,-114,-149,-128;
/M: SY='F';  M=-122,-120,-133,-128, 124,-130,-111, -97,-124, -61, -98,-123,-133, -24,-121,-120,-115,-102, -87,  41;
/M: SY='K';  M=  -9,-124, -25, -43,-126,-116,-104,-126,  97,-124,-113,  -7,-113,   2,  53, -53, -38,-120,-122,-113;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='K';  M=  40,-117, -15,   1, -44,  -6,-107,-115,  42, -86,  14,  24, -56,  -1,  12,  32,   6, -31,-125,-113;
/M: SY='N';  M=  19,  10,   2,-106, -13, -65,  29, -61,-104, -77,-111,  87,-118,-102,-109,  56, -31, -20,-128,   8;
/M: SY='W';  M=-122, -40,-144,-127,   5,-122,-133,-117,-119,-114,-116,-139,-128,-119,-122,-127,-131,-129, 176,  53;
/M: SY='P';  M=  10,-122, -16,-101,-124,   3,  -2,-118,  53, -50,-113,  37,  68,-101, -20,  22, -21, -28,-127,-117;
/I:         I=-45; MD=-115;
/M: SY='T';  M= -19,-120, -39,  39, -70, -51, -35,  14,   4, -18,-105,  10,-114,  40,   2,   3,  50,  -2,-128,-112; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='H';  M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84;
/M: SY='K';  M= -65,-123, -59, -91, -32,-116,-105,-123, 110,-123,-112,  11,-112, -28, -20, -67,-104, -50,-120,-111;
/M: SY='A';  M=  34,-117, -37,  -1, -46, -70,-109, -13,  29,  22,-101,  10,-116,  22,   7,  23,   1, -10,-124,-110;
/M: SY='I';  M= -44,-119,-121, -55,  -5,-126, -33,  42,  22,  40, -29, -35,-122, -45, -50, -28,  11,  41,  19,  -6;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='H';  M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84;
/M: SY='K';  M=  -1,-121, -18,  23, -27,-116, -37, -70,  63, -17,-107, -26,  -5, -12,   0,  -2,  30, -23,  17,  16;
/M: SY='P';  M=   3,-120, -14,  21, -41, -79, -19,  -8,  30,  18,  28, -25,  32, -18, -30,  13,  -1,   2,-125,-110;
/M: SY='A';  M=  53, -15,  18,  13, -15,  -8,-113, -31, -10, -15,  10, -67,  12,   0, -51, -15, -10,  -8,  29,-111;
/M: SY='K';  M=  10,-121,   4,  -3, -59,   4,-108, -49,  60, -21,-109,  25,  14,   5, -11, -22,  15, -19,-125,-114;
/M: SY='P';  M=  27,-121,   5,  21, -67,  11,-108, -74, -19, -33,  -4,   8,  44,  43, -29,   8, -31,   1,-125, -41;
/M: SY='P';  M=  16,-121,  -5,  14,-115,  20,-109, -19,  22, -16,  14,  22,  26, -21, -18, -50,  13,  -4,   0,  -9;
/M: SY='N';  M=  14, -38,   5,  18, -32, -57,-106, -41,  12,  -2,  12,  43, -38,  15,  -3,  10,  20, -17, -13, -19;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 13 in 13 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C6H2-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
13 sequences

MAP11_DANRE (Q4QRK0), MAP11_DICDI (Q54WU3), MAP11_HUMAN (P53582), 
MAP11_MOUSE (Q8BP48), MAP1A_ARATH (Q9SLN5), MAP1B_PLAF7 (Q8IJP2), 
MAP1_BOVIN  (A6QLA4), MAP1_CHICK  (Q5ZIM5), MAP1_PONAB  (Q5RBF3), 
MAP1_SCHPO  (O59730), MAP1_XENLA  (Q7ZWV9), MAP1_XENTR  (Q5I0A0), 
MAP1_YEAST  (Q01662)
» more

PDB
[Detailed view]
5 PDB

4IU6; 7SEK; 8BQD; 8BQX; 8P2K