PROSITE logo
Due to maintenance work, this service will be unavailable from Mon Nov 11 17:30 until Tue Nov 12 09:00 CET. Apologies for the inconvenience.

PROSITE entry PS52013


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] ZF_C6H2
Accession [info] PS52013
Entry type [info] MATRIX
Date [info] 03-MAY-2023 CREATED;
03-MAY-2023 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52013
Associated ProRule [info] PRU01357

Name and characterization of the entry

Description [info] Zinc finger C6H2-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=56;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=51;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6833065; R2=0.0077849; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1968; N_SCORE=18.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=491; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-54; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='M';  M=  -7,-120, -42,  20,-118,  19,-110,   0,  14, -79,  51, -36,  11,  17,-107,  44,  14, -18,-126, -45;
/M: SY='H';  M=  -8,-122, -36, -48, -72, -25,  55,  13,   0, -38,  10,  30,   3,  23,  47, -24, -13,  11, -20, -25;
/M: SY='P';  M=   5,-119,-114, -65, -21, -83,  23,  27,  23, -10,  17, -56,  35, -12, -32,   5,  33,  26,-124, -37;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='S';  M=  32,  21, -12,  27, -59,-109, -23, -39, -63, -31, -35,   2, -59,  47,-108,  54,  -8, -11,  49,-110;
/M: SY='G';  M=   3,-118, -35,-112, -48,  72,-112,-120, -40, -45,-114,  18,-115,-106,   9,  36,  32, -44,-125,-117;
/I:         I=-29; MD=-75;
/M: SY='P';  M=  -8, -28, -23,  -1, -54, -48, -47, -40, -75, -23,-132, -44,  63,-131,-140, -24, -52, -78,-151,-141; D=-29;
/I:         I=-29; MD=-75;
/M: SY='G';  M= -63,-149,  -3,   5, -55,  32,-132,-154, -74,-153,-145,  20, -30,  15, -74,   6,-130,-151,-153,-143; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/I:         I=-28; MD=-70;
/M: SY='G';  M= -37,-142, -46,-133,-147,  68,-134, -80, -17, -92,-138, -16,  -1,-128,-134,   1, -57,-142,-144,-141; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='K';  M= -76,-141, -69, -12,-141,  12, -19, -56,  59, -67,-129,  12,-132,  -6, -32, -46, -59, -25,-143,-132; D=-28;
/I:         I=-28; DM=-70;
/M: SY='N';  M=  -3,-122,  11,  38,-124,   6, -41, -75,  21, -78,-113,  50,  43,  34,-103,   3, -32,  -2,-128, -52;
/M: SY='T';  M=  36, -31,  -2,   6,-119, -34, -19, -58,  33, -25,-108,  19,  16, -41,-104, -24,  57,  -2,-129,-115;
/M: SY='P';  M=  39, -42,  -4,  15, -36, -56,-111, -78, -11, -51,-111,  16,  63, -17,-110,  14,  46, -33,-128,-116;
/M: SY='S';  M=  52, -36, -51, -50, -35,  18,-110,-116,  -6,-117,  -1, -36, -58, -48,   8,  67,  -6, -33,-125,-114;
/I:         I=-29; MD=-75;
/M: SY='K';  M= -44,-120, -37, -28, -15,-114, -11, -71,  62, -38,-109,  33,-114,  26,  30,  21,  48, -46,-126,-110; D=-29;
/I:         I=-29; MD=-75;
/M: SY='L';  M=-119, -26,-132,-127,  23, -68,-117, -45, -69,  77,  57,  -9,-134,-121,-124, -72,-114, -96,-120, -29; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='Q';  M=  -9,  27,-106,  10, -45,-117, -53,-124,  46,-122,-113, -42,-117,  90,  16,  13, -16, -57,-127,-115; D=-29;
/I:         I=-29; DM=-75;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='P';  M=-114,-139,-114,-102,-133,-116,-116,-122, -33,-131,-118,-119, 132, -22,-119,-111,-107,-126,-126,-130;
/M: SY='T';  M= -70,-116,-111,-107,-110,-120, -16,  22,  51,   5, -98, -12,-115, -20, -32, -31,  74,  30,-128,-109;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='L';  M= -74,-120, -63, -60, -45,-125,   0,  40,  33,  41,   4, -13,-121,  33, -37, -69,   1,  34,-124,-105;
/M: SY='K';  M= -11, -39,  16,  34,-127, -76,-104, -60,  87,-123,-114,  13,-111,  26, -38,  -2, -32,-119,-125,-115;
/M: SY='L';  M= -16,-120, -34,  -9,  -9,-124, -18,   9,  -4,  67,  14,  -9,-123,  36, -20, -68, -67, -95,-118, -15;
/M: SY='G';  M= -36,-122,  18,  -5,-127,  71,-107,-128,  40, -85,-118,  52, -63,  -8, -55,  -1,-105, -66,-126,-119;
/M: SY='I';  M= -31,-120, -51,-117, -38, -78, -27,  66,   1,  58, -86, -23,-124, -26,   5,-116, -59,  -7,-121,-104;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='P';  M=  -4, -25,  12,   9,-148, -73, -37,-141,  -5, -89,-136, -60,  57, -34, -25, -21, -19, -82,-150,-140; D=-20;
/I:         I=-20; DM=-51;
/M: SY='P';  M= -19,-124,  16, -17,-121,  23,  10,   9,   9, -86,-111,  -4,  50, -50, -35,  15,   2,  16,-130, -53; D=-20;
/I:         I=-20; DM=-51;
/M: SY='S';  M=  33, -39,-108, -52,-123, -27,-111, -19, -39,-121,-115, -15,-115, -13, -53,  92, -31, -63,-130,-117; D=-20;
/I:         I=-20; DM=-51;
/M: SY='Y';  M= -26,  -7,-125,-122,  81,-126,  10, -10,-117, -28,-100, -53, -25, -50, -21, -22, -63,  -6,  -9,  85; D=-20;
/I:         I=-20; DM=-51;
/M: SY='F';  M=-125,-122,-136,-132, 124,-132,-113, -99,-127, -91,-100,-126,-135,-136,-124,-123,-117,-104, -89,  40; D=-20;
/I:         I=-20; DM=-51;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='S';  M= -41,   6,  17,-105,-123,  25,-108,-121,-106,-124,-117,  10,-112,-101,-112,  90,  45,-114,-132,-116;
/M: SY='Q';  M= -70,-131,-101, -16,-135,-115, -97,-122, -28,-119,-106, -26,  -7, 132, -30, -51,-108, -59,-121,-110;
/M: SY='E';  M=  13,-122,  68,  70,-126, -36,-105,-118, -21, -58,-115, -26, -55,  16,-105, -20,  16, -14,-132,-117;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='C';  M=-109, 159,-128,-128,-119,-124, -18,-126,-124,-116,-116,-114,-139,-131,-130,-111,-109,-114,-149,-128;
/M: SY='F';  M=-122,-120,-133,-128, 124,-130,-111, -97,-124, -61, -98,-123,-133, -24,-121,-120,-115,-102, -87,  41;
/M: SY='K';  M=  -9,-124, -25, -43,-126,-116,-104,-126,  97,-124,-113,  -7,-113,   2,  53, -53, -38,-120,-122,-113;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='K';  M=  40,-117, -15,   1, -44,  -6,-107,-115,  42, -86,  14,  24, -56,  -1,  12,  32,   6, -31,-125,-113;
/M: SY='N';  M=  19,  10,   2,-106, -13, -65,  29, -61,-104, -77,-111,  87,-118,-102,-109,  56, -31, -20,-128,   8;
/M: SY='W';  M=-122, -40,-144,-127,   5,-122,-133,-117,-119,-114,-116,-139,-128,-119,-122,-127,-131,-129, 176,  53;
/M: SY='P';  M=  10,-122, -16,-101,-124,   3,  -2,-118,  53, -50,-113,  37,  68,-101, -20,  22, -21, -28,-127,-117;
/I:         I=-45; MD=-115;
/M: SY='T';  M= -19,-120, -39,  39, -70, -51, -35,  14,   4, -18,-105,  10,-114,  40,   2,   3,  50,  -2,-128,-112; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='H';  M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84;
/M: SY='K';  M= -65,-123, -59, -91, -32,-116,-105,-123, 110,-123,-112,  11,-112, -28, -20, -67,-104, -50,-120,-111;
/M: SY='A';  M=  34,-117, -37,  -1, -46, -70,-109, -13,  29,  22,-101,  10,-116,  22,   7,  23,   1, -10,-124,-110;
/M: SY='I';  M= -44,-119,-121, -55,  -5,-126, -33,  42,  22,  40, -29, -35,-122, -45, -50, -28,  11,  41,  19,  -6;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='H';  M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84;
/M: SY='K';  M=  -1,-121, -18,  23, -27,-116, -37, -70,  63, -17,-107, -26,  -5, -12,   0,  -2,  30, -23,  17,  16;
/M: SY='P';  M=   3,-120, -14,  21, -41, -79, -19,  -8,  30,  18,  28, -25,  32, -18, -30,  13,  -1,   2,-125,-110;
/M: SY='A';  M=  53, -15,  18,  13, -15,  -8,-113, -31, -10, -15,  10, -67,  12,   0, -51, -15, -10,  -8,  29,-111;
/M: SY='K';  M=  10,-121,   4,  -3, -59,   4,-108, -49,  60, -21,-109,  25,  14,   5, -11, -22,  15, -19,-125,-114;
/M: SY='P';  M=  27,-121,   5,  21, -67,  11,-108, -74, -19, -33,  -4,   8,  44,  43, -29,   8, -31,   1,-125, -41;
/M: SY='P';  M=  16,-121,  -5,  14,-115,  20,-109, -19,  22, -16,  14,  22,  26, -21, -18, -50,  13,  -4,   0,  -9;
/M: SY='N';  M=  14, -38,   5,  18, -32, -57,-106, -41,  12,  -2,  12,  43, -38,  15,  -3,  10,  20, -17, -13, -19;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 13 in 13 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C6H2-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
13 sequences

MAP11_DANRE (Q4QRK0), MAP11_DICDI (Q54WU3), MAP11_HUMAN (P53582), 
MAP11_MOUSE (Q8BP48), MAP1A_ARATH (Q9SLN5), MAP1B_PLAF7 (Q8IJP2), 
MAP1_BOVIN  (A6QLA4), MAP1_CHICK  (Q5ZIM5), MAP1_PONAB  (Q5RBF3), 
MAP1_SCHPO  (O59730), MAP1_XENLA  (Q7ZWV9), MAP1_XENTR  (Q5I0A0), 
MAP1_YEAST  (Q01662)
» more

PDB
[Detailed view]
5 PDB

4IU6; 7SEK; 8BQD; 8BQX; 8P2K