General rule information
[?]
Accession |
PRU01357 |
Dates |
15-DEC-2022 (Created) 15-DEC-2022 (Last updated, Version 1) |
Predictors |
PROSITE; PS52013; ZF_C6H2
|
Name |
Zinc finger C6H2-type |
Function |
The C6H2-type zinc finger is essential for the normal processing function of MetAP1 and may be important for the proper functional alignment of MetAP1 on the ribosomes. It is a protein-protein interaction domain. |
Propagated annotation
[?]
case (<Feature:PS52013:4=[CH]> and <Feature:PS52013:9=[CH]> and <Feature:PS52013:33=[CH]> and <Feature:PS52013:37=[CH]>) or (<Feature:PS52013:19=[CH]> and <Feature:PS52013:22=[CH]> and <Feature:PS52013:45=[CH]> and <Feature:PS52013:49=[CH]>)
end case
Similarity |
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. |
case (<Feature:PS52013:4=[CH]> and <Feature:PS52013:9=[CH]> and <Feature:PS52013:33=[CH]> and <Feature:PS52013:37=[CH]>) or (<Feature:PS52013:19=[CH]> and <Feature:PS52013:22=[CH]> and <Feature:PS52013:45=[CH]> and <Feature:PS52013:49=[CH]>)
GO:0046872; Molecular function: metal ion binding.
end case
case (<Feature:PS52013:4=[C]> and <Feature:PS52013:9=[C]> and <Feature:PS52013:33=[C]> and <Feature:PS52013:37=[C]>) and (<Feature:PS52013:19=[C]> and <Feature:PS52013:22=[C]> and <Feature:PS52013:45=[H]> and <Feature:PS52013:49=[H]>)
From: PS52013 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ZN_FING
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from
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to
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C6H2-type #
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else case (<Feature:PS52013:4=[CH]> and <Feature:PS52013:9=[CH]> and <Feature:PS52013:33=[CH]> and <Feature:PS52013:37=[CH]>) and (<Feature:PS52013:19=[CH]> and <Feature:PS52013:22=[CH]> and <Feature:PS52013:45=[CH]> and <Feature:PS52013:49=[CH]>)
ZN_FING
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from
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to
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C6H2-type #; atypical
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else
ZN_FING
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from
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to
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C6H2-type #; degenerate
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end case
BINDING
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4
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4
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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[CH]
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1
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BINDING
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9
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9
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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[CH]
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1
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BINDING
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19
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19
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
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[CH]
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2
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BINDING
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22
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22
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
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[CH]
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2
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BINDING
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33
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33
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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[CH]
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1
|
BINDING
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37
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37
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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|
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[CH]
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1
|
BINDING
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45
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45
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
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[CH]
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2
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BINDING
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49
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49
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
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[CH]
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2
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Additional information
[?]
Size range |
53-59 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
Q5RBF3 (MAP1_PONAB) |
Scope |
Eukaryota |
Comments |
None |
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