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annotation rule: PRU01357

General rule information [?]

Accession PRU01357
Dates 15-DEC-2022 (Created)
15-DEC-2022 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS52013; ZF_C6H2
Name Zinc finger C6H2-type
Function The C6H2-type zinc finger is essential for the normal processing function of MetAP1 and may be important for the proper functional alignment of MetAP1 on the ribosomes. It is a protein-protein interaction domain.

Propagated annotation [?]

Comments [?]

case (<Feature:PS52013:4=[CH]> and <Feature:PS52013:9=[CH]> and <Feature:PS52013:33=[CH]> and <Feature:PS52013:37=[CH]>) or (<Feature:PS52013:19=[CH]> and <Feature:PS52013:22=[CH]> and <Feature:PS52013:45=[CH]> and <Feature:PS52013:49=[CH]>)
Cofactor Zn(2+)
end case

Similarity Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.

Gene Ontology [?]

case (<Feature:PS52013:4=[CH]> and <Feature:PS52013:9=[CH]> and <Feature:PS52013:33=[CH]> and <Feature:PS52013:37=[CH]>) or (<Feature:PS52013:19=[CH]> and <Feature:PS52013:22=[CH]> and <Feature:PS52013:45=[CH]> and <Feature:PS52013:49=[CH]>)
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

end case

Features [?]

case (<Feature:PS52013:4=[C]> and <Feature:PS52013:9=[C]> and <Feature:PS52013:33=[C]> and <Feature:PS52013:37=[C]>) and (<Feature:PS52013:19=[C]> and <Feature:PS52013:22=[C]> and <Feature:PS52013:45=[H]> and <Feature:PS52013:49=[H]>)
From: PS52013
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     to       C6H2-type #        
else case (<Feature:PS52013:4=[CH]> and <Feature:PS52013:9=[CH]> and <Feature:PS52013:33=[CH]> and <Feature:PS52013:37=[CH]>) and (<Feature:PS52013:19=[CH]> and <Feature:PS52013:22=[CH]> and <Feature:PS52013:45=[CH]> and <Feature:PS52013:49=[CH]>)
ZN_FING     from     to       C6H2-type #; atypical        
ZN_FING     from     to       C6H2-type #; degenerate        
end case

BINDING     4     4       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     9     9       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     19     19       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2
BINDING     22     22       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2
BINDING     33     33       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     37     37       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     45     45       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2
BINDING     49     49       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2

Additional information [?]

Size range 53-59 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q5RBF3 (MAP1_PONAB)
Comments None


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