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PROSITE entry PS52046


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PURL: https://purl.expasy.org/prosite/signature/PS52046

Direct ScanProsite submission
General information about the entry

Entry name [info] ZF_C2HC_NPR
Accession [info] PS52046
Entry type [info] MATRIX
Date [info] 27-NOV-2024 CREATED;
27-NOV-2024 DATA UPDATE;
27-NOV-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52046
Associated ProRule [info] PRU01391

Name and characterization of the entry

Description [info] Zinc finger C2HC NPR-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=15;
/DISJOINT: DEFINITION=PROTECT; N1=2; N2=14;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8376615; R2=0.0060848; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=931; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=602; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-59; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='V';  M=  39,-115,-122,-115,-108, -54,-120, -83,-105,  -8, -96,-117,-123,-111,  50, -44,-101,  83,-129,-111;
/M: SY='C';  M=  22,  87,-114,-110, -67,-108,-115,-113,-111,-117, -39,-106,  63,-109, -55,  72, -37,  -6,   0,-116;
/M: SY='T';  M=  -1,-116,   4, -10, -44,   8,-111,  14,-106, -42, -54,  47,-115, -24, -49,   2,  57,  23,-130,-113;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='V';  M=  21,-116,-160, -49,-108,  29,-121, -14,-113,  -2,   8,-113,-121,-113,   1, -14, -72,  73,-128,-112;
/M: SY='D';  M= -25,-127, 106,  48,-129,-114,  29,-129, -99, -73,-122, -29,-113,  21,-106,-102,-106,-126,-138, -23;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='D';  M= -70,-126,  75,  47,-125, -26,-104, -33, -40, -34,-115, -18,  -3, -95,  59,   0, -31,-118,-132,-129;
/M: SY='G';  M=   8,-121,  44,  25,-120,  57,-110, -98,-106, -29,  -1, -10,-115, -12, -20,  -7,  -4,  -1,-127, -45;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='W';  M=  28,  37, -20, -61, -52,   0,  11, -49,-109, -49,-111, -50,  29, -13, -59,  23,   4, -67, 119,-102;
/M: SY='H';  M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84;
/M: SY='D';  M= -38,-119,  75,  32, -32, -39, -41, -70,-104, -51,   4, -26,-114,  -1,-111, -99,  54,  33,-134,-112;
/M: SY='A';  M=  73,  -9,-110,-109,-120,  23,  70,-119,-107,-118,-110, -23,-116,-104, -10,  29, -41, -58,-126, -20;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/M: SY='R';  M= -57, -25,-111,-104,-118, -15,  15,-121, -16, -77, -32, -28,  -1, -97,  91,  -5,  40, -69,  61,-108;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 20 in 20 different sequences
Number of true positive hits 20 in 20 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C2HC NPR-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
20 sequences

COCH_PEA(G8GTN7), NBCL_LOTJA  (G3LSH3), NBCL_LUPAN  (A0A0K0PU92), 
NBCL_LUPLU  (S4VGD0), NH51_ORYSJ  (Q2RAQ5), NH52_ORYSJ  (Q2QXZ2), 
NOOT1_MEDTR (Q2HW56), NOOT2_MEDTR (A0A072VIM5), NPR1_ARATH  (P93002), 
NPR1_MALHU  (E7BQV0), NPR1_ORYSI  (Q5D0W8), NPR1_ORYSJ  (Q9FDY4), 
NPR2_ARATH  (Q9SZI3), NPR2_ORYSJ  (Q0JJ01), NPR3_ARATH  (Q8L746), 
NPR3_ORYSJ  (Q75HA6), NPR4_ARATH  (Q5ICL9), NPR5_ARATH  (Q9ZVC2), 
NPR5_ORYSJ  (A2CIR7), NPR6_ARATH  (Q9M1I7)
» more

PDB
[Detailed view]
4 PDB

7MK2; 7MK3; 7TAC; 7TAD