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ProRule PRU01391


General rule information [?]

Accession PRU01391
Dates 3-JUL-2024 (Created)
4-JUL-2024 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS52046; ZF_C2HC_NPR
Name Zinc finger C2HC NPR-type
Function A prominent feature of NPR proteins is the presence of a conserved cysteine cluster within the BTB domain. These cysteine residues together with a conserved histidine (C-X-D-X(2,3)-C-X-H-X(2)-C) form a zinc finger motif that bridges the BTB domain with the ANKs.
Scope(s) Eukaryota
Magnoliopsida
Example(s) P93002 (NPR1_ARATH);

Propagated annotation [?]

Keywords [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS52046
Key From To Description Tag Condition FTGroup
case <Feature:PS52046:4=[C]> and <Feature:PS52046:9=[C]> and <Feature:PS52046:11=[H]> and <Feature:PS52046:14=[C]>
ZN_FING from to /note="C2HC NPR-type #"
else case <Feature:PS52046:4=[CH]> and <Feature:PS52046:9=[CH]> and <Feature:PS52046:11=[HC]> and <Feature:PS52046:14=[CH]>
ZN_FING from to /note="C2HC NPR-type #; atypical"
else
ZN_FING from to /note="C2HC NPR-type #; degenerate"
end case
BINDING 4 4 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 9 9 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 11 11 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 14 14 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
MOD_RES 10 10 /note="S-nitrosocysteine" C

Additional information [?]

Size range 15-15 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]