ProRule PRU01391
General rule information
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Accession | PRU01391 |
Dates | 3-JUL-2024 (Created)
4-JUL-2024 (Last updated, Version 2) |
Data class | Domain; |
Predictors |
PROSITE; PS52046; ZF_C2HC_NPR |
Name | Zinc finger C2HC NPR-type |
Function | A prominent feature of NPR proteins is the presence of a conserved cysteine cluster within the BTB domain. These cysteine residues together with a conserved histidine (C-X-D-X(2,3)-C-X-H-X(2)-C) form a zinc finger motif that bridges the BTB domain with the ANKs. |
Scope(s) |
Eukaryota Magnoliopsida |
Example(s) | P93002 (NPR1_ARATH); |
Propagated annotation
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Keywords
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Metal-binding | |
Zinc | |
end case | |
Zinc-finger |
Gene Ontology
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case <FTGroup:1> | |
GO:0008270; Molecular function:zinc ion binding |
Features
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From: PS52046 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
case <Feature:PS52046:4=[C]> and <Feature:PS52046:9=[C]> and <Feature:PS52046:11=[H]> and <Feature:PS52046:14=[C]> | ||||||||||||
ZN_FING | from | to | /note="C2HC NPR-type #" | |||||||||
else case <Feature:PS52046:4=[CH]> and <Feature:PS52046:9=[CH]> and <Feature:PS52046:11=[HC]> and <Feature:PS52046:14=[CH]> | ||||||||||||
ZN_FING | from | to | /note="C2HC NPR-type #; atypical" | |||||||||
else | ||||||||||||
ZN_FING | from | to | /note="C2HC NPR-type #; degenerate" | |||||||||
end case | ||||||||||||
BINDING | 4 | 4 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
BINDING | 9 | 9 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
BINDING | 11 | 11 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
BINDING | 14 | 14 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
MOD_RES | 10 | 10 | /note="S-nitrosocysteine" | C |
Additional information
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Size range | 15-15 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [20] All [ 20 ]
- Retrieve set of proteins with 3D structure for this domain