PROSITE entry PS52051
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| Entry name [info] | CXC_MSL2 |
| Accession [info] | PS52051 |
| Entry type [info] | MATRIX |
| Date [info] |
05-FEB-2025 CREATED;
05-FEB-2025 DATA UPDATE; 05-FEB-2025 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC52051 |
| Associated ProRule [info] | PRU01396 |
Name and characterization of the entry
| Description [info] | CXC MSL2-type domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=52; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=47; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.9816434; R2=0.0081472; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1046; N_SCORE=12.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=310; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-51; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='P'; M= -26, -83, -73, -11, -75, -9, -75, -4, 5, -6, -19, 3, 34, -5, -20, -30, -12, 24, -89, -76; /M: SY='E'; M= -9, -86, -62, 45, -43, -65, -69, -38, 44, -54, -10, -66, 15, 2, 17, -59, -8, -42, -85, -76; /M: SY='K'; M= -47, -87, -71, -60, -54, -27, -69, -39, 63, -36, -71, -64, 16, -56, 52, -1, -67, -38, -84, -74; /M: SY='K'; M= -48, -89, -27, -17, -88, -49, 21, -78, 66, -87, -75, -45, 33, 7, 29, -18, -62, -85, -20, -74; /M: SY='G'; M= -64, -84, -73, -77, -80, 60, -23, 10, -5, -29, -70, -3, -26, -71, -15, -19, 11, -29, -87, -78; /M: SY='C'; M= -71, 144, -91, -91, -81, -86, -91, -88, -86, -78, -79, -77,-101, -94, -93, -73, -71, -75,-111, -92; /M: SY='R'; M= -72, -89, -69, -58, -87, -42, -64, -91, 59, -86, -75, -62, -79, -50, 83, -9, -70, -85, -84, -74; /M: SY='C'; M= -71, 144, -91, -91, -81, -86, -91, -88, -86, -78, -79, -77,-101, -94, -93, -73, -71, -75,-111, -92; /M: SY='G'; M= -34, -86, -74, -84, -92, 91, -80, -99, -76, -95, -84, -60, -78, -75, -24, -59, -77, -92, -83, -87; /I: I=-36; MD=-90; /M: SY='R'; M= -49, -88, -75, -75, -83, -34, -75, -9, -22, -44, -16, 38, -87, -6, 39, -31, 21, -5, -97, -59; D=-36; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='A'; M= 55, -75, -73, -68, -55, -26, -75, -72, -32, -77, -72, -23, -76, -14, -10, 35, 11, -12, 1, -76; /M: SY='T'; M= -51, -75, -38, -70, -15, 13, -74, -72, -19, -77, -73, 5, -73, -68, -73, 35, 71, -21, -91, -73; /M: SY='Q'; M= -16, -24, -70, -61, -84, -14, -22, -40, 17, -41, -15, -36, 29, 59, -45, 12, 12, -17, -87, -75; /M: SY='N'; M= 19, -21, -65, -45, -40, -5, -68, -47, -46, -14, -10, 57, -79, 0, -44, -2, 23, -32, -89, -43; /M: SY='P'; M= -72, -92, -69, -63, -91, -30, -72, -80, 11, -89, -77, 30, 96, 9, -70, -50, -39, -31, -90, -86; /M: SY='G'; M= -58, -81, -69, -72, -87, 57, -73, -85, -20, -88, -80, -5, 5, -29, -74, 56, -16, -39, -88, -81; /M: SY='K'; M= -46, -82, -73, -42, -75, -52, -9, -52, 48, 0, -63, -44, 6, -31, 11, -5, -5, 27, -88, -72; /I: I=-38; MD=-97; /M: SY='L'; M= -42, -33, -81, -78, -65, -86, -76, -58, -23, 54, -22, 4, -88, -73, 6, -15, 22, -61, -89, -71; D=-38; /I: I=-38; MD=-97; /M: SY='T'; M= -72, -81, -78, -81, -87, -88, -88, -76, -77, -82, -79, -67, -79, -82, -86, -56, 94, -37,-108, -85; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='C'; M= -71, 144, -91, -91, -81, -86, -91, -88, -86, -78, -79, -77,-101, -94, -93, -73, -71, -75,-111, -92; /M: SY='R'; M= -73, 70, -79, -70, -19, -69, -22, -16, -31, -26, -67, -70, -87, -23, 78, -26, -71, -14, -87, -54; /M: SY='G'; M= -61, -82, -65, -78, -89, 77, -72, -93, -71, -93, -82, 48, -78, -71, -47, -14, -2, -88, -88, -84; /M: SY='Q'; M= -67, -86, -62, -54, -81, -73, -11, -81, -15, -80, -70, 34, -77, 93, -56, 13, 11, -81, -80, 23; /M: SY='R'; M= -76, -92, -72, -60, -86, -86, -62, -92, 7, -85, -74, -65, -84, -49, 104, -70, -75, -86, -85, -72; /M: SY='C'; M= -71, 143, -91, -91, -79, -87, -90, -85, -87, -42, -76, -77,-101, -94, -93, -74, -71, -74,-109, -90; /M: SY='P'; M= -46, -96, -76, -66, -87, -77, -76, -64, -69, -67, -77, -78, 106, -44, -16, -6, -22, -83, 0, -22; /I: I=-31; MD=-79; /M: SY='C'; M= -72, 143, -92, -92, -82, -88, -92, -89, -88, -80, -80, -78,-103, -96, -94, -75, -72, -77,-112, -93; D=-31; /I: I=-31; MD=-79; /M: SY='Y'; M= -83, -91, -84, -86, 37, -90, -51, -66, -78, -62, -61, -84, -95, -75, -75, -78, -77, -71, -40, 117; D=-31; /I: I=-31; MD=-79; /M: SY='S'; M= -12, -69, -64, -58, -69, -64, -66, -7, 55, -62, -3, -55, -68, -54, -51, 63, -12, 40, -81, -65; D=-31; /I: I=-31; MD=-79; /M: SY='N'; M= 12, -70, 27, 20, -78, -32, -53, -71, -11, -77, -69, 88, -69, -31, -58, 20, -13, -14, -89, -71; D=-31; /I: I=-31; MD=-79; /M: SY='F'; M= -40, -77, 11, 4, 55, 42, -52, -74, 7, -69, -67, -11, -72, 2, 33, 13, -62, -72, -67, -18; D=-31; /I: I=-31; MI=-79; MD=-79; IM=-79; DM=-79; /M: SY='N'; M= -26, -74, -51, -53, -73, -12, -55, -72, 70, -22, -64, 78, -70, -17, -20, -53, -13, -38, -80, -17; D=-31; /I: I=-31; DM=-79; /M: SY='S'; M= 14, -68, -59, -23, -65, -17, -63, -68, -43, -74, -68, -52, 40, -53, -39, 87, -23, -11, -82, -69; /M: SY='C'; M= -62, 149, -80, -78, -72, -77, -79, -79, -32, -70, -69, -67, -91, -80, -4, -64, -62, -67, -99, -81; /I: I=-20; MD=-51; /M: SY='A'; M= 44, -70, -19, 31, -48, -66, 6, -2, -6, -9, -33, -12, -68, -36, -11, -3, 22, -4, -77, -1; D=-20; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='D'; M= -51, -14, 86, 5, -79, 14, 30, -80, -11, -52, -41, 36, -69, -22, -24, -9, -58, -53, -90, -26; /M: SY='C'; M= -36, 148, -82, -82, -8, -77, -80, -77, -78, -68, -69, -69, -92, -85, -83, -65, -63, -66, -93, -17; /M: SY='H'; M= -21, -77, -61, -56, -68, -47, 92, -13, 41, -25, -58, 3, 19, -34, 21, 4, -59, -3, -82, -12; /M: SY='C'; M= -36, 148, -83, -83, -72, -79, -83, -76, -79, -42, -69, -70, -93, -86, -85, -66, -63, -34,-101, -83; /M: SY='V'; M= -52, 15, -70, -41, 3, -79, -31, -14, 11, -18, -54, -3, -77, 20, 50, -63, -12, 57, -80, -61; /M: SY='G'; M= -19, 2, -62, -75, -84, 87, -69, -89, -68, -87, -77, 44, -72, -67, -76, -35, -29, -83, -81, -80; /M: SY='C'; M= -37, 147, -82, -82, -75, -79, -7, -81, -45, -73, -72, -69, -46, -84, -83, -66, -64, -70,-103, -83; /M: SY='K'; M= -25, -81, -61, -51, -81, 7, 36, -83, 72, -79, -68, -15, -70, 17, 53, -58, -13, -78, -79, -66; /M: SY='N'; M= -38, -71, -40, -60, -80, -54, -47, -78, -31, -63, -72, 119, -76, -53, -59, -48, -50, -80, -98, -75; /M: SY='P'; M= -67, -92, -69, -38, -86, -70, -73, -77, -66, -86, -74, -73, 118, -68, -77, -5, -19, -81, 19, -82; /M: SY='H'; M= -41, -81, -66, -64, 29, -77, 112, -68, -61, -2, -54, -18, -79, -45, 17, -65, -42, -40, -71, 52; /M: SY='K'; M= -64, -79, -19, -3, -78, -11, -61, -31, 74, -59, 19, 25, -6, -14, 0, -41, 13, -62, -80, -59; /M: SY='E'; M=-130,-151,-101, 42,-154,-146,-123,-155,-111,-147,-143,-127,-125,-104,-121,-127,-131,-147,-150,-144; /M: SY='D'; M=-138,-151, 49,-101,-158,-134,-123,-156,-125,-155,-154,-105,-137,-124,-133,-126,-127,-153,-173,-141; /M: SY='Y'; M=-141,-152,-141,-144, -89,-148,-107,-127,-135,-123,-120,-142,-153,-131,-132,-136,-136,-132, -97, 64; /M: SY='V'; M=-122,-136,-153,-147,-124,-154,-156, -89,-145,-110,-112,-149,-149,-148,-146,-136,-121, 33,-158,-132; /M: SY='E'; M=-130,-151,-101, 42,-154,-146,-123,-155,-111,-147,-143,-127,-125,-104,-121,-127,-131,-147,-150,-144; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 4 in 4 different sequences |
| Number of true positive hits | 4 in 4 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | CXC MSL2-type |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
4 sequences
MSL2_CHICK (A0A1D5NVS8), MSL2_DROME (P50534), MSL2_HUMAN (Q9HCI7), MSL2_MOUSE (Q69ZF8)» more
|
| PDB [Detailed view] |
3 PDB
2LUA; 4RKG; 4RKH |