ProRule PRU01396

General rule information [?]

Accession	PRU01396
Dates	19-SEP-2024 (Created) -- (Last updated, Version 1)
Data class	Domain;
Predictors	PROSITE; PS52051; CXC_MSL2
Name	CXC MSL2-type domain
Function	The MSL2-type CXC dpmain has a DNA binding function as it can mediate the DNA binding of the MSL2-MSL1 heteromer.
Scope(s)	Eukaryota Metazoa
Example(s)	Q69ZF8 (MSL2_MOUSE);

Propagated annotation [?]

Comments [?]

SIMILARITY

Belongs to the MSL2 family.

Keywords [?]

Metal-binding
Zinc
end case
Nucleus
Chromosome

Gene Ontology [?]

GO:0072487; Cellular component:MSL complex
case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS52051
Key	From	To	Description	Tag	Condition	FTGroup
DOMAIN	from	to	/note="CXC MSL2-type #"
BINDING	6	6	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[C]	1
BINDING	6	6	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[C]	2
BINDING	8	8	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[C]	1
BINDING	20	20	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[C]	1
BINDING	20	20	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		[C]	3
BINDING	25	25	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[C]	1
BINDING	27	27	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[C]	2
BINDING	34	34	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[C]	2
BINDING	34	34	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		[C]	3
BINDING	37	37	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[C]	2
BINDING	39	39	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		[C]	3
BINDING	42	42	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		[C]	3

Additional information [?]

Size range	52-52 amino acids
Related rules	None
Fusion	None
Repeats	1
Topology	Undefined

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Eukaryota	[4]
All	[ 4 ]

Retrieve set of proteins with 3D structure for this domain