PROSITE entry PS52111
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PURL: https://purl.expasy.org/prosite/signature/PS52111
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General information about the entry
| Entry name [info] | FV_VP35_NPBP |
| Accession [info] | PS52111 |
| Entry type [info] | MATRIX |
| Date [info] |
04-NOV-2026 CREATED;
04-NOV-2026 DATA UPDATE; 04-NOV-2026 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC52111 |
| Associated ProRule [info] | PRU01455 |
Name and characterization of the entry
| Description [info] | Filoviruses viral protein 35 (VP35) nucleoprotein (NP) binding peptide (NPBP) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=28; /DISJOINT: DEFINITION=PROTECT; N1=3; N2=26; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2244177; R2=0.0155984; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=563; N_SCORE=10.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=339; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-9; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='M'; M=-14, 0, -4, -2, -9,-16,-19, 12, -9,-10, -4, 18, -6,-20, -3,-11,-12,-12, -9,-31, -6, -6; /M: SY='W'; M=-14, -4,-35, 3, -4,-17,-15, 3,-26,-11,-25,-19, -8, -3, -6,-13,-10,-14,-27, 21, 0, -5; /M: SY='G'; M= 6, 8,-25, 12, -5,-31, 29,-14,-33,-12,-25,-21, 4,-15,-12,-17, 2,-12,-23,-26,-25, -8; /M: SY='P'; M= 1, -9,-24, -5, 0,-25, -9,-15,-20,-10,-30,-20, -4, 36, -5,-15, 17, 6,-19,-35,-25, -5; /M: SY='E'; M= -4, 5,-24, 9, 32,-29,-14, -1,-25, 4,-23,-15, 3, -5, 23, -1, 12, -1,-24,-31,-18, 28; /M: SY='Y'; M=-12,-23,-20,-26,-23, 28,-29, -9, 7,-19, 10, 3,-20,-27,-22,-16,-14, 0, 7, -1, 29,-23; /M: SY='M'; M= -2, -9,-14,-16,-12, -8,-15, -9, 1,-10, -2, 19, -6,-14, -3,-10, 7, 16, 2,-28, -8, -7; /M: SY='G'; M= -5, 6,-26, 10, 2,-33, 19, -7,-31, -7,-28,-17, 6,-14, 7, -9, 8, -8,-26,-28,-21, 4; /M: SY='W'; M=-10,-15,-34,-15, -4,-16,-16,-12,-22, 3,-24,-13,-13,-17, 9, -1, -9,-12,-24, 39, 3, 4; /M: SY='V'; M= -7,-30,-18,-34,-28, 12,-32,-27, 29,-26, 20, 13,-26,-28,-27,-22,-17, -6, 31,-20, 0,-28; /M: SY='S'; M= 16, -2,-10, -6, -4,-18, -4,-14,-16,-10,-22,-16, 4,-10, -4,-12, 30, 22, -6,-34,-18, -4; /M: SY='E'; M=-12, 18,-30, 30, 52,-32,-18, 0,-32, 8,-22,-22, 4, -2, 16, -2, 0,-10,-30,-32,-20, 34; /M: SY='Q'; M= 4, -4,-26, -6, 4,-34, 6, -3,-23, -1,-20, -7, -2,-12, 26, -3, 2,-10,-24,-20,-17, 15; /M: SY='L'; M= -8,-30,-20,-32,-24, 6,-32,-24, 28,-28, 37, 18,-28,-28,-22,-22,-24, -8, 22,-22, -2,-24; /M: SY='M'; M=-10,-22,-20,-30,-20, 2,-22, -4, 20,-14, 26, 52,-22,-22, -4,-12,-22,-10, 10,-20, 0,-12; /M: SY='T'; M= 0, 0,-10,-10,-10,-10,-20,-20,-10,-10,-10,-10, 0,-10,-10,-10, 20, 50, 0,-30,-10,-10; /M: SY='G'; M= 0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20, 0,-20,-20,-20, 0,-20,-30,-20,-30,-20; /M: SY='R'; M=-13, 4,-28, 1, 5,-25,-16, -3,-28, 34,-27,-12, 11,-15, 8, 37, -6, -8,-22,-24,-12, 5; /M: SY='I'; M= -8,-30,-21,-34,-26, 4,-34,-26, 33,-28, 29, 18,-26,-26,-22,-24,-21, -8, 27,-22, -2,-26; /M: SY='P'; M= -2,-12,-28, -6, 0,-26,-12,-16,-20,-10,-30,-20, -8, 51, -6,-16, 9, 2,-22,-34,-26, -6; /M: SY='I'; M=-10,-30,-20,-34,-27, 18,-32,-25, 26,-28, 26, 14,-26,-28,-26,-22,-21, -8, 22,-17, 3,-27; /M: SY='D'; M=-11, 32,-23, 42, 10,-30,-11, -6,-30, -4,-25,-24, 14,-10, -2,-10, 10, 8,-20,-38,-18, 4; /M: SY='Q'; M=-10, 13,-26, 17, 19,-33,-18, 0,-24, 4,-20,-12, 5, -9, 27, 0, 4, 2,-24,-28,-14, 23; /M: SY='I'; M= -6,-30,-22,-36,-30, 0,-36,-30, 42,-26, 16, 16,-24,-24,-24,-26,-16, -6, 38,-24, -4,-30; /I: I=-6; MI=0; MD=-29; IM=0; DM=-29; /M: SY='F'; M=-16,-30,-18,-38,-30, 65,-30,-22, 6,-28, 10, 2,-22,-30,-38,-20,-18, -8, 9, 2, 22,-30; /M: SY='Q'; M= -6,-10, -9,-11, -1,-23, -3,-14,-13,-11,-14, -8, -9,-18, 1,-13, -5,-11,-10,-27,-18, 0; /M: SY='D'; M= 7, 11, 8, 12, -3,-26,-12,-15,-25,-10,-19,-19, 0,-16,-10,-17, 3, 0,-13,-34,-21, -7; /M: SY='S'; M= -1, -1,-17, -8,-11,-13,-13,-12, 3,-14,-13, -7, 10,-17, -9,-14, 12, 5, 2,-34,-14,-11; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 10 in 10 different sequences |
| Number of true positive hits | 10 in 10 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | VP35 NPBP |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
10 sequences
VP35_EBORE (Q91DE0), VP35_EBORR (Q8JPY0), VP35_EBOSU (Q5XX07), VP35_EBOZ5 (Q6V1Q9), VP35_EBOZM (Q05127), VP35_MABVA (Q1PD52), VP35_MABVM (P35259), VP35_MABVO (Q6UY68), VP35_MABVP (Q03039), VP35_MABVR (Q1PDC9)» more
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| PDB [Detailed view] |
10 PDB
pdb_00004ypi; pdb_00004zta; pdb_00004ztg; pdb_00004zti; pdb_00005f5o; pdb_00005xsq; pdb_00006oaf; pdb_00008usn; pdb_00008ust; pdb_00009ip2 » more |