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PROSITE documentation PDOC00308 [for PROSITE entry PS00357]

Histone H2B signature


Histone H2B is one of the four histones, along with H2A, H3 and H4, which forms the eukaryotic nucleosome core. Using alignments of histone H2B sequences [1,2,E1], we selected a conserved region in the C-terminal part of H2B.

Last update:

November 1995 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

HISTONE_H2B, PS00357; Histone H2B signature  (PATTERN)


1AuthorsWells D.E. Brown D.
TitleHistone and histone gene compilation and alignment update.
SourceNucleic Acids Res. 19:2173-2188(1991).
PubMed ID2041803

2AuthorsThatcher T.H. Gorovsky M.A.
TitlePhylogenetic analysis of the core histones H2A, H2B, H3, and H4.
SourceNucleic Acids Res. 22:174-179(1994).
PubMed ID8121801


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