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PROSITE entry PS00463


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PURL: https://purl.expasy.org/prosite/signature/PS00463

Direct ScanProsite submission
General information about the entry

Entry name [info] ZN2_CY6_FUNGAL_1
Accession [info] PS00463
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00378

Name and characterization of the entry

Description [info] Zn(2)-C6 fungal-type DNA-binding domain signature.
Pattern [info] 
[GASTPV]-C-x(2)-C-[RKHSTACW]-x(2)-[RKHQ]-x(2)-C-x(5,12)-C-x(2)-C-x(6,8)-
C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 383 in 383 different sequences
Number of true positive hits 373 in 373 different sequences
Number of 'unknown' hits 1
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 90
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 97.64 %
Recall (true positives / (true positives + false negatives)) 80.56 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] zinc at position 2
Site [info] zinc at position 4
Site [info] zinc at position 9
Site [info] zinc at position 11
Site [info] zinc at position 13
Site [info] zinc at position 15
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 373 sequences 

AACUR_ASPA1 (A0A1L9WLK2), ABL7_LEPMJ  (E5A7E3), ACE2_HYPJE  (Q96WN6), 

ACLZ_ASPOR  (Q2UPC3), ACR2_NEUCR  (P78704), ACRR_ASPA1  (A0A1L9WQN2), 
ACTTR_ALTAL (Q589W9), ACU15_NEUCR (P87000), ACUM_ASPFU  (E5DG73), 
ADAR_ASPNC  (A2QX26), ADAR_ASPNG  (G3KLH2), AFLR_ASPFN  (P41765), 
AFLR_ASPPA  (P43651), AFLR_ASPPU  (Q6UEG8), AFLR_DOTSN  (M2YIY2), 
AFLR_EMENI  (P52957), AFOA_EMENI  (Q5BEK1), AFTR1_ALTAL (Q96VB4), 
AFTR2_ALTAL (Q50LF9), AFUMD_ASPFC (B0Y568), AGN10_PAEDI (A0A411PQP1), 
AGN11_PAEDI (A0A411PQN2), AHR1_CANAL  (Q5A4F3), AKTR1_ALTAL (Q9P4V0), 
AKTR2_ALTAL (Q9P4U8), AKTR3_ALTAL (V5XYQ2), ALT13_ALTAL (A0A3G9HCC8), 
AMDR_ASPFU  (Q4WK35), AMDR_ASPOR  (Q06157), AMDR_EMENI  (P15699), 
AMTR1_ALTAL (C9K7C2), AOIH_ASPOR  (Q2TXQ7), APDR_EMENI  (Q5ATG6), 
ARA1_PYRO7  (G4MNH3), ARAR_ASPNC  (A2QJX5), ARAR_EMENI  (Q5BGE2), 
ARGR2_YEAST (P05085), ARO80_YEAST (Q04052), ASAR_ASPFN  (B8N0F0), 
ASG1_CANAL  (Q59LV8), ASG1_YEAST  (P40467), ASR3_SARSH  (A0A2U8U2K7), 
AT326_ASPTN (Q0D158), ATF_ASPTN   (Q0CJ56), ATG2_PICPA  (Q9HFR4), 
ATND_ARTSZ  (A0A455LXK6), ATNE_ARTSZ  (A0A455M2Z1), ATNN_EMENI  (C8V3N0), 
ATRR_ASPFU  (Q4WI89), ATRR_ASPOR  (Q2UEH7), ATRR_EMENI  (Q5B4H2), 
AURR1_GIBZE (I1RF54), AZAR_ASPNA  (G3XMC5), AZPB6_ASPTN (Q0CF68), 
BEA4_GIBF5  (S0EFU6), BIK5_GIBF5  (S0E028), BOA13_BOTFB (G0LEU0), 
BUT80_GIBZE (I1RV20), CALC_PENDC  (A0A1V6PAU0), CAT8_YEAST  (P39113), 
CBF3B_YEAST (P40969), CGHD_CHAGB  (Q2HBN3), CHA4_YEAST  (P43634), 
CLAE_PASFU  (P0CU72), CPAR_ASPOZ  (F5HN75), CTB8_CERBT  (A0A2G5ICB4), 
CTB8_CERNC  (A0ST46), CTF1A_FUSVN (P52958), CTF1B_FUSVN (P52959), 
CTNR_MONPU  (Q1ERI1), CTNR_MONRU  (A0A162J452), CURR_ASPTE  (L7X8G0), 
CZF1_CANAL  (Q5A0W9), CZF1_CANAW  (P28875), DAL81_YEAST (P21657), 
DBAA_EMENI  (C8V4J5), DEP6_ALTBR  (D2E9X1), DEP6_FUSLA  (A0A0M9ER64), 
DHC4_ALTCI  (A0A0N6WJC7), DIBT_PESMI  (A0A5B8YUW5), DMR14_CRYX8 (A0A4P8DK24), 
ECDB_ASPRU  (K0E2F6), ECM22_YEAST (Q05958), EDS1_YEAS1  (B3LNB2), 
EDS1_YEAS2  (C7GXX9), EDS1_YEAS6  (B5VDZ9), EDS1_YEAS7  (A6ZKX7), 
EDS1_YEAS8  (D3UEC9), EDS1_YEAST  (P38073), ELCR_PHANO  (Q0UI05), 
ERT1_CANAW  (C4YLC3), ERT1_CANDC  (B9WLA7), ERT1_CANGA  (Q6FML7), 
ERT1_DEBHA  (Q6BY37), ERT1_EREGS  (Q754V2), ERT1_KLULA  (Q6CKI5), 
ERT1_KOMPG  (C4R1K8), ERT1_LACTC  (C5E2K7), ERT1_PICGU  (A5DF43), 
ERT1_PICST  (A3LQV7), ERT1_YEAS1  (B3LMS3), ERT1_YEAS2  (C7GMR4), 
ERT1_YEAS7  (A6ZLH8), ERT1_YEAS8  (D3UEY7), ERT1_YEAST  (P38140), 
ERT1_ZYGRC  (C5E1J9), EUPR_PHOSX  (A0A4P8GG91), FCR1_CANAX  (O93870), 
FDB21_FUSPC (K3VZ28), FDB3_FUSPC  (K3UIH8), FDB3_GIBM7  (W7N466), 
FDB94_GIBM7 (W7MVT8), FFSR_ASPFV  (A0A7M4BDQ2), FGR27_CANAL (Q59NX5), 
FGSR_GIBZE  (I1RC73), FLUF_NEUCR  (O13360), FSA6_FUSSF  (A0A0E4AZF8), 
FSL7_GIBZE  (I1S160), FSR6_GIBF5  (S0DW94), FTF2_FUSO4  (A0A0J9WP80), 
FUB10_FUSO4 (A0A0D2YFZ9), FUB10_GIBF5 (S0DRY0), FUB10_GIBM7 (W7MS18), 
FUB12_FUSO4 (A0A0D2YFZ7), FUB12_GIBF5 (S0DRX3), FUB12_GIBM7 (W7MT41), 
FUM21_GIBM7 (W7LKW1), FUMR_ASPFU  (Q4WAY8), FUP7_FUSPR  (A0A1L7VEP9), 
GAL4_ASPNC  (A2QYD4), GAL4_YEAST  (P04386), GEDR_ASPTN  (Q0CCY1), 
GLIZ_ASPFU  (Q4WMK0), GME70_PESMI (A0A5B8YUX3), GRT1_SCHPO  (Q9C469), 
GSM1_CANAL  (Q59WB9), GSM1_CANAW  (C4YDV1), GSM1_CANDC  (B9W8A8), 
GSM1_CANGA  (Q6FLG1), GSM1_CANTT  (C5MCK5), GSM1_CLAL4  (C4Y4V1), 
GSM1_DEBHA  (Q6BJW8), GSM1_EREGS  (Q754J3), GSM1_KLULA  (Q6CK33), 
GSM1_KOMPG  (C4QV17), GSM1_LODEL  (A5DU46), GSM1_PICGU  (A5DRJ2), 
GSM1_PICST  (A3LWY2), GSM1_VANPO  (A7TQK0), GSM1_YEAS1  (B3LQ10), 
GSM1_YEAS2  (C7GR11), GSM1_YEAS7  (A6ZQM3), GSM1_YEAS8  (C8ZBB1), 
GSM1_YEAST  (P42950), GSM1_ZYGRC  (C5DX31), HAL9_YEAST  (Q12180), 
HAP1_YEAS1  (B3RHD9), HAP1_YEAS2  (C7GQY3), HAP1_YEAS7  (A7A1D7), 
HAP1_YEAS8  (C8ZDL9), HAP1_YEASK  (G2WJ80), HAP1_YEAST  (P0CE41), 
HAP1_YEASX  (P0CS82), HASA_ASPFC  (B0XWT0), HASF_ASPFC  (B0XWK6), 
HIMB_ASPJA  (A0A2Z5TJB0), HIMD_ASPJA  (A0A2Z5U1Z1), IACK_PESFW  (A0A1J0HSL8), 
KOJR_ASPFN  (B8NL21), KOJR_ASPOR  (Q2U5H9), LAC9_KLULA  (P08657), 
LEPE_ASPFN  (B8NJG9), LEUR_YEAST  (P08638), LFC1_FLAVE  (A0A455LJ99), 
LOVE_ASPTE  (Q9Y7D3), LOVE_ASPTN  (Q0C8L8), LYS14_YEAST (P40971), 
MACR_PENTR  (A0A2P1DP89), MAL13_YEAST (P53338), MAL33_YEAST (P38157), 
MAL63_YEASX (P10508), MAR1_CANGA  (Q6FXJ5), MDPE_EMENI  (Q5BH32), 
MFL3_PHOSM  (A0A3G1DJJ7), MLCR_PENCI  (Q8J0F2), MOC3_SCHPO  (Q9UT46), 
MOKH_MONPI  (Q3S2U4), MPSE_MACPH  (K2QYX9), MRR1_CANAL  (Q5A4G2), 
MRR2_CANAL  (Q59MJ1), NIRA_EMENI  (P28348), NIT4_NEUCR  (P28349), 
NOSA_ASPFU  (Q4WPL7), NOTL_ASPSM  (E1ACQ7), NOTL_ASPVE  (L7WMF4), 
NOTQ_ASPVE  (L7WMF9), NSCR_ARTBC  (D4AWG9), NSCR_ARTGP  (E4V2N6), 
NSCR_ARTOC  (C5FM61), NSCR_ASPFU  (Q4WA59), NSCR_NEOFI  (A1D8J1), 
NSCR_TRIEC  (F2PWS9), NSCR_TRIRC  (F2T0M4), NSCR_TRIT1  (F2S703), 
NSCR_TRIVH  (D4CZZ6), OAF1_YEAST  (P39720), OAF3_CANGA  (Q6FJJ1), 
OAF3_EREGS  (Q75BN0), OAF3_KLULA  (Q6CXS0), OAF3_LACTC  (C5DKJ7), 
OAF3_VANPO  (A7TGQ2), OAF3_YEAS1  (B3LRD9), OAF3_YEAS2  (C7GX75), 
OAF3_YEAS6  (B5VML1), OAF3_YEAS7  (A7A024), OAF3_YEAST  (P36023), 
OAF3_ZYGRC  (C5DUX2), OPDJ_PENO1  (S8AKF3), OPDL_PENO1  (S7Z806), 
OPDR_PENO1  (S7Z6W7), ORF10_PENRF (W6QB19), ORYO_ASPOR  (Q2TXG2), 
PATL_ASPCL  (A1CFL9), PATL_PENEN  (A0A075TXZ8), PBCR_EMENI  (A0A1U8QL22), 
PDR1_CANGA  (Q6FXU7), PDR1_YEAST  (P12383), PDR3_YEAST  (P33200), 
PDR8_YEAST  (Q06149), PFMAH_PESFW (W3X9K7), PHM6_PYRSX  (A0A2Z5XAK7), 
PHMR_PHANO  (Q0V6Q7), PHOR1_DIALO (A0A8J9RZ21), PHOR2_DIALO (A0A142I731), 
PIG11_CLAP2 (M1W853), PIGI_MONRU  (A0A1P8VFQ8), PIP2_YEAST  (P52960), 
PK81E_PSEFD (M3APK0), POXB_PENO1  (S8B3H6), POXB_PENOX  (A0A1W5T1T3), 
PPR1_YEAST  (P07272), PRIB_LENED  (P49412), PRLF_FUNXX  (A0A089GT84), 
PRLR_FUNXX  (A0A089FQI6), PRO1_NEUCR  (Q9P326), PRTT_ASPCL  (A1CHV7), 
PRTT_ASPFC  (B0Y6K1), PRTT_ASPFU  (Q4WPQ8), PRTT_ASPNC  (A2QJF9), 
PRTT_ASPOR  (A7BJS7), PRTT_EMENI  (Q5B8L0), PRTT_PENRW  (B6HRH5), 
PTAR2_PESFW (A0A067XMN9), PTAR3_PESFW (A0A067XMT7), PUL4_KLULA  (Q6CSN1), 
PUT3_YEAST  (P25502), PYNR_ASPNC  (A5ABG4), PYTR_ASPTN  (Q0CZG5), 
QA1F_NEUCR  (P11638), QUTA_EMENI  (P10563), RDR1_GIBZE  (Q4I0C5), 
RDR1_YEAST  (Q08904), RDS1_YEAST  (P25611), RDS2_YEAST  (P19541), 
RGLT_ASPFC  (B0XQ41), RGLT_ASPFU  (Q4WTI4), RGLT_EMENI  (A0A1U8QZJ7), 
RGT1_CANGA  (Q6FLP2), RGT1_EREGS  (Q750N3), RGT1_LACTC  (C5DGQ7), 
RGT1_VANPO  (A7TE38), RGT1_YEAS1  (B3LR49), RGT1_YEAS2  (C7GP35), 
RGT1_YEAS7  (A6ZZS7), RGT1_YEAST  (P32862), RGT1_ZYGRC  (C5E4G1), 
ROB1_CANAL  (A0A1D8PFP2), RSC30_YEAST (P38781), RSC3_YEAST  (Q06639), 
SDNS_SORAA  (A0A1B4XBH9), SEF1_CANAL  (Q59UY7), SEF1_EREGS  (Q74Z37), 
SEF1_KLULA  (P87164), SEF1_YEAST  (P34228), SIP4_YEAST  (P46954), 
SIRZ_LEPMC  (Q6Q877), SORR1_HYPJQ (G0R6T4), SORR1_PENRW (B6HN75), 
SORR2_HYPJQ (G0R6T2), SPHG_ASPFC  (A0A8F5CBH1), STB4_YEAST  (P50104), 
STB5_CANGA  (Q6FQY1), STB5_YEAST  (P38699), STHR_PHANO  (Q0UK54), 
SUC1_CANAL  (P33181), TAC1_CANAL  (A0A1D8PN96), TAS2_PYRO7  (G4N134), 
TASR_HAPIR  (A0A0F7GH49), TAZR_ASPTN  (Q0CS89), TBS1_YEAST  (P38114), 
TCPZ_CLAP2  (M1W424), TEA1_YEAST  (P47988), TENR_BEAB2  (J4VZG1), 
TERR_ASPTN  (Q0D1P5), TF177_GIBF5 (S0EJF2), TF1A1_FUSO4 (A0A0J9VYS2), 
TF1A2_FUSO4 (A0A0J9WAS0), TF1A3_FUSO4 (A0A0J9W3S9), TF1C1_FUSO4 (A0A0J9W9G2), 
TF1C2_FUSO4 (A0A0J9WVC0), TF1C3_FUSO4 (A0A0J9VT58), TF29_ZYMTI  (F9XMW5), 
TF88_EMENI  (Q5AY42), TF90_EMENI  (Q5AY40), TFC7_DOTSN  (M2XJV1), 
TF_NEOBT(Q6F5E1), THI1_SCHPO  (P36598), THI2_YEAST  (P38141), 
THI5_SCHPO  (O94278), TOG1_YEAST  (P39961), TRAC_PENCR  (A0A481WNP6), 
TROPK_TALSN (B8M9K6), TSF1_ELSFA  (B0ZT45), TUR1_CRYNH  (J9VXS6), 
UAY_EMENI   (P49413), UGA3_YEAST  (P26370), UME6_CANAL  (Q59MD2), 
UME6_YEAST  (P39001), UPC2_CANAL  (Q59QC7), UPC2_YEAST  (Q12151), 
URC2_LACKL  (Q6YFE6), URC2_YEAST  (Q04411), USTR_ASPFN  (B8NM76), 
VDTR1_BYSSP (A0A443HK05), VRTR2_PENAE (D7PHY7), WAR1_CANAL  (Q59VQ8), 
WAR1_YEAST  (Q03631), WOR2_CANAL  (Q5ANB1), YAKB_SCHPO  (Q09922), 
YANR_ASPNA  (G3Y415), YAO7_SCHPO  (Q10086), YAOB_SCHPO  (G2TRN9), 
YAS8_SCHPO  (Q10144), YCN3_SCHPO  (O59780), YCUA_SCHPO  (O59830), 
YCV2_SCHPO  (O74541), YF54_SCHPO  (O14130), YFN1_SCHPO  (Q1MTM9), 
YGDC_SCHPO  (O94569), YGDG_SCHPO  (O94573), YH7G_SCHPO  (O60130), 
YH7H_SCHPO  (O60131), YHDD_SCHPO  (Q9P6I9), YI35_SCHPO  (Q9HE16), 
YI4C_SCHPO  (G2TRT1), YII3_SCHPO  (Q9UTN0), YJ74_SCHPO  (O74915), 
YJU6_YEAST  (P39529), YKM1_SCHPO  (Q9C0Z1), YKN4_SCHPO  (Q9HDX1), 
YKW2_YEAST  (P35995), YL054_YEAST (Q12244), YL278_YEAST (Q05854), 
YL8B_SCHPO  (Q9UTA7), YLV1_SCHPO  (O94392), YN25_SCHPO  (O59741), 
YN28_SCHPO  (O59744), YN92_YEAST  (P53749), YOG2_SCHPO  (O74308), 
YP196_YEAST (Q06595), YRM1_YEAST  (Q12340), YRR1_YEAST  (Q12172), 
ZNF1_YEAST  (P43551)
» more

UniProtKB/Swiss-Prot
False negative sequences		 90 sequences 

AACUB_ASPA1 (A0A1L9WLF2), ACUK_AJECG  (C0NCM1), ACUK_AJECN  (A6R213), 

ACUK_AJEDR  (C5GF27), ACUK_ARTBC  (D4AL61), ACUK_ARTGP  (E4UP58), 
ACUK_ARTOC  (C5FP02), ACUK_ASPCL  (A1C602), ACUK_ASPFC  (B0XVV1), 
ACUK_ASPFU  (Q4WHD1), ACUK_ASPNC  (A2QFG8), ACUK_ASPOR  (Q2UMM2), 
ACUK_ASPTN  (Q0CHR0), ACUK_BLAGS  (C5JT39), ACUK_BOTFB  (A6SP81), 
ACUK_CHAGB  (Q2GSA4), ACUK_COCP7  (C5PHH6), ACUK_EMENI  (Q5AW62), 
ACUK_FUSV7  (C7YM38), ACUK_NEOFI  (A1DG01), ACUK_NEUCR  (Q7RUA4), 
ACUK_PARBA  (C1GR85), ACUK_PARBD  (C1G966), ACUK_PENRW  (B6HSQ3), 
ACUK_PHANO  (Q0U7C8), ACUK_PODAN  (B2AR36), ACUK_PYRTR  (B2W978), 
ACUK_SCLS1  (A7EAG1), ACUK_SORMK  (D1ZRZ5), ACUK_TALMQ  (B6Q3B6), 
ACUK_TALSN  (B8LT44), ACUK_TRIVH  (D4D2Y6), ACUK_UNCRE  (C4JFE4), 
ALCR_EMENI  (P21228), AZPB7_ASPTN (Q0CF67), C6TF_LEPMJ  (E5AE39), 
EOT1_SOLLC  (K4B6C9), EQXR_GIBF5  (S0DRT4), ERT11_YARLI (Q6C5G3), 
ERT12_YARLI (Q6C764), ERT1_COPC7  (A8N767), ERT1_MYCMD  (Q4PD88), 
ERT1_POSPM  (B8PBQ6), ERT1_SCHCM  (D8Q8R5), GRGC_PENSQ  (A0A6F8RPE5), 
IMQK_ASPFN  (B8NI28), KPEA_ASPOR  (Q2UJJ4), LCSL_PURLI  (A0A179G9G5), 
LRP1_ARATH  (Q94CK9), MPSB_MACPH  (K2RKH8), NSRM_ASPN1  (A0A2I1C3T0), 
OPS3_BEAB2  (J4KLU1), PHIO_FUNX7  (A0A348HAZ0), PHM2_PYRSX  (A0A2Z5XAS1), 
PHOD1_DIALO (A0A8J9RRX1), PHOD2_DIALO (A0A142I723), PIG20_CLAP2 (M1WCE9), 
PIGB_MONRU  (R4NN02), PVHR_TALVA  (A0A3T0QHS4), RGT1_KLULA  (Q6CIL8), 
SAT20_STACB (A0A084AFG9), SHI1_ORYSJ  (Q652K4), SHI_ARATH   (Q9XGX0), 
SRS1_ARATH  (Q9SD40), SRS2_ARATH  (O65517), SRS3_ARATH  (Q9SJT8), 
SRS4_ARATH  (Q9SI19), SRS5_ARATH  (Q9LQZ5), SRS6_ARATH  (Q9M2U4), 
SRS7_ARATH  (Q9FXH7), SRS8_ARATH  (F4KH89), TSTO_TALSN  (B8MKY7), 
XILB_PENRW  (B6H998), XLNR_ASPCL  (A1C7P9), XLNR_ASPFC  (B0XUL1), 
XLNR_ASPFN  (B8N6M6), XLNR_ASPFU  (Q4WZV6), XLNR_ASPKA  (Q96WP8), 
XLNR_ASPNC  (A2R5W7), XLNR_ASPNG  (O42804), XLNR_ASPOR  (Q2UD93), 
XLNR_ASPTN  (Q0CV52), XLNR_EMENI  (Q5AVS0), XLNR_NEOFI  (A1DIC0), 
XLNR_PYRO7  (G4MZJ4), YBCB_SCHPO  (O13658), YC79_SCHPO  (O94490), 
YG55_SCHPO  (O60056), YIT3_SCHPO  (Q9P7H9), YN2B_SCHPO  (O59746)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

SCGR7_HUMAN (A0A286YF01)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			9 sequences
			


			
KRA51_HUMAN (Q6L8H4), KRA59_HUMAN (P26371), SCGR2_HUMAN (A0A286YFB4), 

			
SCGR3_HUMAN (A0A286YF60), SCGR4_HUMAN (A0A286YEV6), SCGR5_HUMAN (A0A286YF46), 
SCGR6_HUMAN (A0A286YF77), SCGR8_HUMAN (A0A286YFG1), SCGR9_HUMAN (P0DSO2)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			26 PDB
			


			pdb_00001ajy; pdb_00001aw6; pdb_00001cld; pdb_00001d66; pdb_00001hwt; pdb_00001pyc; pdb_00001pyi; pdb_00001qp9; pdb_00001zme; pdb_00002er8; pdb_00002ere; pdb_00002erg; 
			
				pdb_00003coq; pdb_00006f07; pdb_00006gys; pdb_00006k15; pdb_00006kw3; pdb_00006kw4; pdb_00006kw5; pdb_00006v8o; pdb_00006v92; pdb_00007k79; pdb_00007k7g; pdb_00007uik; 
				pdb_00007uio; pdb_00008ow1
			
			

			» more