Prokaryotic ribonuclease III (EC 188.8.131.52) (gene rnc)  is an enzyme that
digests double-stranded RNA. It is involved in the processing of ribosomal RNA
precursors and of some mRNAs. RNase III is evolutionary related  to the
Fission yeast pac1, a ribonuclease that probably inhibits mating and
meiosis by degrading a specific mRNA required for sexual development.
Yeast ribonuclease III (gene RNT1), a dsRNA-specific nuclease that cleaves
eukaryotic preribosomal RNA at various sites.
Caenorhabditis elegans hypothetical protein F26E4.13.
Paramecium bursaria chlorella virus 1 protein A464R.
Synechocystis strain PCC 6803 hypothetical protein slr0346.
Fission yeast hypothetical protein SpAC8A4.08c, a protein with a N-terminal
helicase domain and a C-terminal RNase III domain.
Caenorhabditis elegans hypothetical protein K12H4.8, a protein with the
same structure as SpAC8A4.08c.
These proteins share regions of sequence similarity; one of which is a highly
conserved stretch of 9 residues which we use as a signature pattern.
December 2004 / Pattern and text revised.
PROSITE methods (with tools and information) covered by this documentation:
Nashimoto H. Uchida H.
DNA sequencing of the Escherichia coli ribonuclease III gene and its mutations.
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