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PROSITE documentation PDOC00513 [for PROSITE entry PS00594] |
It has been shown [1] that some proteins involved in the transport of aromatic amino acids in Escherichia coli and related bacteria are evolutionary related; these permeases are:
These permeases are proteins of about 400 to 420 amino acids which probably contain 11 or 12 transmembrane regions. The best conserved domain is a stretch of 20 residues which seems to be located in a cytoplasmic loop between the first and second transmembrane region.
Last update:November 1997 / Pattern and text revised.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Sarsero J.P. Wookey P.J. Gollnick P. Yanofsky C. Pittard A.J. |
Title | A new family of integral membrane proteins involved in transport of aromatic amino acids in Escherichia coli. | |
Source | J. Bacteriol. 173:3231-3234(1991). | |
PubMed ID | 2022620 |