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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00776


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PURL: https://purl.expasy.org/prosite/signature/PS00776

Direct ScanProsite submission
General information about the entry

Entry name [info] GH11_1
Accession [info] PS00776
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00622
Associated ProRule [info] PRU10062

Name and characterization of the entry

Description [info] Glycosyl hydrolases family 11 (GH11) active site signature 1.
Pattern [info] 
[PSA]-[LQ]-x-E-[YF]-Y-[LIVM](2)-[DE]-x-[FYWHN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 96 in 95 different sequences
Number of true positive hits 96 in 95 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.97 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] active_site at position 4
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 95 sequences 

EIX1_BOTFB  (A0A384JXV5), EIX1_VERDV  (G2X4G0), EIX2_VERDV  (G2X0L1), 

EIX3_VERLO  (A0A0G4KL96), EIX4_VERDV  (G2X5X8), EIX_HYPRU   (Q9UVF9), 
EIX_PEND1   (K9GHZ3), XS20E_NEOPA (B8YG19), XY11A_BOTFB (B3VSG7), 
XY11A_BOTFU (Q2LMP0), XY11A_CELJA (Q59674), XY11A_HUMIN (V9TS54), 
XY11A_MYCMD (Q4P0L3), XY11A_PSEXY (P83513), XY11B_CELJA (Q8VP72), 
XY11B_HUMIN (A0A0B5JC15), XYN11_PAEBA (V9TXH2), XYN1B_HUMIN (P55334), 
XYN1_AURPU  (Q96TR7), XYN1_CLAPU  (O74716), XYN1_COCCA  (Q06562), 
XYN1_HYPJQ  (G0R947), XYN1_HYPJR  (P36218), XYN1_LEUGO  (A6YAP7), 
XYN1_PYRGI  (P0CT48), XYN1_PYRO7  (P0CT49), XYN2_HUMIN  (Q9HGE1), 
XYN2_HYPJQ  (G0RUP7), XYN2_HYPJR  (P36217), XYN2_RHIOR  (W0HJ53), 
XYN2_TRIHA  (B5A7N4), XYN3_ASPKW  (P33557), XYN3_PENPR  (A0A2U7R6V5), 
XYN3_PYRGI  (Q92244), XYN3_PYRO7  (G4MWS3), XYN4_ASPNG  (Q12550), 
XYN4_PYRGI  (Q92245), XYN4_PYRO7  (G4NA54), XYN5_ASPNC  (A2R4D1), 
XYN5_ASPNG  (Q12549), XYN6_ASPNG  (Q6QJ75), XYNA1_THEST (Q8GJ44), 
XYNA2_THEST (P33558), XYNA_ASPAW  (P55328), XYNA_ASPCL  (A1CCU0), 
XYNA_ASPFC  (B0XXF3), XYNA_ASPFN  (B8NKE9), XYNA_ASPFU  (Q4WG11), 
XYNA_ASPNG  (P55329), XYNA_ASPOR  (Q9HFA4), XYNA_ASPTN  (Q0CFS3), 
XYNA_ASPTU  (P55331), XYNA_AURPU  (Q12562), XYNA_BACPU  (P00694), 
XYNA_BACSU  (P18429), XYNA_BYSSP  (P81536), XYNA_CLOSA  (P17137), 
XYNA_EMENI  (P55332), XYNA_GEOSE  (P45705), XYNA_GIBZE  (I1S2K3), 
XYNA_NEOFI  (A1DJ52), XYNA_NEOPA  (P29127), XYNA_NIACI  (P09850), 
XYNA_PENCI  (Q2PGY1), XYNA_PIRSP  (Q12667), XYNA_RUMFL  (P29126), 
XYNA_SCHCO  (P35809), XYNA_THELA  (O43097), XYNB_ASPCL  (A1CU59), 
XYNB_ASPFC  (B0Y8Q8), XYNB_ASPFN  (B8NJ86), XYNB_ASPFU  (Q4WLV2), 
XYNB_ASPKW  (P48824), XYNB_ASPNC  (A2Q7I0), XYNB_ASPNG  (P55330), 
XYNB_ASPOR  (P87037), XYNB_EMENI  (P55333), XYNB_GIBZE  (I1RII8), 
XYNB_NEOFI  (A1DNU5), XYNB_PENOX  (E7EF85), XYNB_PHACH  (B7SIW1), 
XYNB_STRLI  (P26515), XYNB_STRSQ  (D7EZJ3), XYNB_TALFU  (Q8J0K5), 
XYNC_FIBSS  (P35811), XYNC_NEOPA  (Q9UV68), XYNC_STRCO  (Q9RI72), 
XYNC_STRLI  (P26220), XYNC_TALFU  (Q9HFH0), XYND_CELFI  (P54865), 
XYND_RUMFL  (Q53317), XYNG_VERDA  (Q0ZHI9), XYN_PHACE   (O97402), 
XYN_TRIHA   (P48793), XYS20_NEOPA (A8TGA1)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

EIX2_BOTFB  (A0A384K474), EIX3_VERDV  (G2X8M4), EIX5_VERDV  (G2X4G1)


				
	

	

		PDB
[Detailed view]		
		
			98 PDB
			


			pdb_00001axk; pdb_00001bcx; pdb_00001bk1; pdb_00001bvv; pdb_00001c5h; pdb_00001c5i; pdb_00001enx; pdb_00001hv1; pdb_00001pvx; pdb_00001red; pdb_00001ree; pdb_00001ref; 
			
				pdb_00001t6g; pdb_00001te1; pdb_00001ukr; pdb_00001xnb; pdb_00001xnc; pdb_00001xnd; pdb_00001xxn; pdb_00001xyn; pdb_00001xyo; pdb_00001xyp; pdb_00001yna; pdb_00002b42; 
				pdb_00002b45; pdb_00002b46; pdb_00002bvv; pdb_00002c1f; pdb_00002d97; pdb_00002d98; pdb_00002dcy; pdb_00002dcz; pdb_00002dfb; pdb_00002dfc; pdb_00002qz2; pdb_00002qz3; 
				pdb_00002vg9; pdb_00002z79; pdb_00003exu; pdb_00003hd8; pdb_00003lb9; pdb_00003lgr; pdb_00003ri8; pdb_00003ri9; pdb_00003vzj; pdb_00003vzk; pdb_00003vzl; pdb_00003vzm; 
				pdb_00003vzn; pdb_00003vzo; pdb_00003wp3; pdb_00003wp4; pdb_00004hk8; pdb_00004hk9; pdb_00004hkl; pdb_00004hko; pdb_00004hkw; pdb_00004s2d; pdb_00004s2f; pdb_00004s2g; 
				pdb_00004s2h; pdb_00004xpv; pdb_00004xq4; pdb_00004xqd; pdb_00004xqw; pdb_00005ej3; pdb_00005k7p; pdb_00005k9y; pdb_00005zf3; pdb_00005zh0; pdb_00005ziw; pdb_00005zkz; 
				pdb_00005zo0; pdb_00006jug; pdb_00006jwb; pdb_00006jxl; pdb_00006jzp; pdb_00006k9o; pdb_00006k9r; pdb_00006k9w; pdb_00006k9x; pdb_00006kvv; pdb_00006kw9; pdb_00006kwc; 
				pdb_00006kwd; pdb_00006kwe; pdb_00006kwf; pdb_00006kwg; pdb_00006kwh; pdb_00006qe8; pdb_00007mgu; pdb_00007vug; pdb_00007vuh; pdb_00007vui; pdb_00007vuj; pdb_00007xn9; 
				pdb_00007xna; pdb_00008keu
			
			

			» more