The following proteins seems to be evolutionary related:
Mammalian proliferating-cell nucleolar antigen p120 (gene NOL1) which may
play a role in the regulation of the cell cycle and the increased nucleolar
activity that is associated with the cell proliferation.
Yeast nucleolar protein NOP2 (or YNA1) which could be involved in nucleolar
function during the onset of growth, and in the maintenance of nucleolar
Yeast hypothetical protein YBL024w.
Bacterial protein sun (also known as fmu).
Escherichia coli hypothetical protein yebU.
Mycobacterium tuberculosis hypothetical protein MtCY21B4.24.
Methanococcus jannaschii hypothetical protein MJ0026.
NOL1 is a protein of 855 residues, NOP2 consists of 618 residues, YBL024w of
684, sun is a protein of about 430 to 450 residues and MJ026 has 274 residues.
They share a conserved central domain which contains some highly conserved
regions. We have selected one these regions as a signature pattern.
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