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PROSITE documentation PDOC00978 [for PROSITE entry PS01271] |
Integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions (sodium symporters) can be grouped, on the basis of sequence and functional similarities into a number of distinct families. One of these families currently consists of the following proteins:
These transporters are proteins of from 430 to 620 amino acids which are highly hydrophobic and which probably contain about 12 transmembrane regions. As a signature pattern, we selected a conserved region which is located in or near the penultimate transmembrane region.
Last update:December 2004 / Pattern and text revised.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Markovich D. Forgo J. Stange G. Biber J. Murer H. |
Title | Expression cloning of rat renal Na+/SO4(2-) cotransport. | |
Source | Proc. Natl. Acad. Sci. U.S.A. 90:8073-8077(1993). | |
PubMed ID | 7690140 |
2 | Authors | Pajor A.M. |
Source | Am. J. Physiol. 270:642-648(1996). |
3 | Authors | Davies J.P. Yildiz F.H. Grossman A. |
Title | Sac1, a putative regulator that is critical for survival of Chlamydomonas reinhardtii during sulfur deprivation. | |
Source | EMBO J. 15:2150-2159(1996). | |
PubMed ID | 8641280 |