|PROSITE documentation PDOC00997 [for PROSITE entry PS01295]|
The bacterial ispD protein  catalyzes the third step of the deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate.
These proteins can be picked up in the database by a pattern centered on a central conserved region that contains a conserved Asp and Arg residues.Last update:
December 2001 / Pattern and text revised.
PROSITE method (with tools and information) covered by this documentation:
|1||Authors||Rohdich F. Wungsintaweekul J. Fellermeier M. Sagner S. Herz S. Kis K. Eisenreich W. Bacher A. Zenk M.H.|
|Title||Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol.|
|Source||Proc. Natl. Acad. Sci. U.S.A. 96:11758-11763(1999).|