|PROSITE documentation PDOC00862 [for PROSITE entry PS50296]|
In budding yeast (Saccharomyces cerevisiae), SUI1 is a translation initiation factor that functions in concert with eIF-2 and the initiator tRNA-Met in directing the ribosome to the proper start site of translation . SUI1 is a protein of 108 residues. Close homologs of SUI1 have been found  in mammals, insects and plants.
SUI1 is also evolutionary related to:
Two eukaryotic proteins also seem to contain a C-terminal SUI1-like domain. These are:
The profile we developed covers the entire C-terminal SUI1-like domain.Last update:
August 2003 / Pattern removed.
PROSITE method (with tools and information) covered by this documentation:
|1||Authors||Yoon H.J., Donahue T.F.|
|Title||The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon.|
|Source||Mol. Cell. Biol. 12:248-260(1992).|
|2||Authors||Fields C.A., Adams M.D.|
|Title||Expressed sequence tags identify a human isolog of the suil translation initiation factor.|
|Source||Biochem. Biophys. Res. Commun. 198:288-291(1994).|