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PROSITE documentation PDOC00862 [for PROSITE entry PS50296] |
In budding yeast (Saccharomyces cerevisiae), SUI1 is a translation initiation factor that functions in concert with eIF-2 and the initiator tRNA-Met in directing the ribosome to the proper start site of translation [1]. SUI1 is a protein of 108 residues. Close homologs of SUI1 have been found [2] in mammals, insects and plants.
SUI1 is also evolutionary related to:
Two eukaryotic proteins also seem to contain a C-terminal SUI1-like domain. These are:
The profile we developed covers the entire C-terminal SUI1-like domain.
Last update:August 2003 / Pattern removed.
PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Yoon H.J. Donahue T.F. |
Title | The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon. | |
Source | Mol. Cell. Biol. 12:248-260(1992). | |
PubMed ID | 1729602 |
2 | Authors | Fields C.A. Adams M.D. |
Title | Expressed sequence tags identify a human isolog of the suil translation initiation factor. | |
Source | Biochem. Biophys. Res. Commun. 198:288-291(1994). | |
PubMed ID | 7904817 |