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PROSITE documentation PDOC50808 [for PROSITE entry PS50808] |
The BED finger which was named after the drosophila proteins BEAF and DREF, is found in one or more copies in cellular regulatory factors and transposases from plants, animals and fungi. The BED finger is an about 50 to 60 amino acid residues domain that contains a characteristic motif with two highly conserved aromatic positions, as well as a shared pattern of cysteines and histidines that is predicted to form a zinc finger. As diverse BED fingers are able to bind DNA, it has been suggested that DNA-binding is the general function of this domain [1].
Some proteins known to contain a BED domain are listed below:
April 2002 / First entry.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Aravind L. |
Title | The BED finger, a novel DNA-binding domain in chromatin-boundary-element-binding proteins and transposases. | |
Source | Trends Biochem. Sci. 25:421-423(2000). | |
PubMed ID | 10973053 |
2 | Authors | Lam E. Kano-Murakami Y. Gilmartin P. Niner B. Chua N.H. |
Title | A metal-dependent DNA-binding protein interacts with a constitutive element of a light-responsive promoter. | |
Source | Plant Cell 2:857-866(1990). | |
PubMed ID | 2152132 | |
DOI | 10.1105/tpc.2.9.857 |
3 | Authors | Coupe S.A. Deikman J. |
Title | Characterization of a DNA-binding protein that interacts with 5' flanking regions of two fruit-ripening genes. | |
Source | Plant J. 11:1207-1218(1997). | |
PubMed ID | 9225464 |