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PROSITE documentation PDOC50863 [for PROSITE entry PS50863]

B3 DNA-binding domain profile





Description

The B3 domain is an about 120-amino acid residue region defined originally as the third basic region of maize VP1, which shares the largest contiguous block of sequence identity with its ortholog, Arabidopsis ABI3. The B3 domain, which has also been called REM domain, is found only in higher plant species. It is characteristic of several transcription factors and has been shown to possess a highly cooperative, sequence-specific DNA-binding activity [1,2,3,4]. The B3 domain can be found in one or more copies and in association with other domains, such as the AP2 DNA-binding domain, an acidic domain or the Aux/IAA-ARF domain (see <PDOC51745>) [2,4].

Some proteins known to contain a B3 domain are listed below:

  • Plant REPRODUCTIVE MERISTEM 1 (REM1) protein.
  • Plant ABSCISIC ACID-INSENSITIVE 3 (ABI3)/VIVIPAROUS1 (VP1) family of regulatory protein.
  • Arabidopsis thaliana proteins related to ABI3/VP1 RAV1 and RAV2.
  • Arabidopsis thaliana AUXIN RESPONSE FACTOR 1 (ARF1).
  • Arabidopsis thaliana FUSCA3 (FUS3).
  • Arabidopsis thaliana LEAFY COTYLEDON 2 (LEC2).

The profile we developed covers the entire B3 domain.

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html --------------------------------------------------------------------------------.

Last update:

March 2004 / First entry.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

B3, PS50863; B3 DNA-binding domain profile  (MATRIX)


References

1AuthorsSuzuki M. Kao C.Y. McCarty D.R.
TitleThe conserved B3 domain of VIVIPAROUS1 has a cooperative DNA binding activity.
SourcePlant Cell 9:799-807(1997).
PubMed ID9165754
DOI10.1105/tpc.9.5.799

2AuthorsKagaya Y. Ohmiya K. Hattori T.
TitleRAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants.
SourceNucleic Acids Res. 27:470-478(1999).
PubMed ID9862967

3AuthorsStone S.L. Kwong L.W. Yee K.M. Pelletier J. Lepiniec L. Fischer R.L. Goldberg R.B. Harada J.J.
TitleLEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development.
SourceProc. Natl. Acad. Sci. U.S.A. 98:11806-11811(2001).
PubMed ID11573014
DOI10.1073/pnas.201413498

4AuthorsFranco-Zorrilla J.M. Cubas P. Jarillo J.A. Fernandez-Calvin B. Salinas J. Martinez-Zapater J.M.
SourcePlant Physiol. 128:418-427(2002).



PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

Miscellaneous

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