We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE entry PS51008
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PURL: https://purl.expasy.org/prosite/signature/PS51008
Direct ScanProsite submission
General information about the entry
| Entry name [info] | MULTIHEME_CYTC |
| Accession [info] | PS51008 |
| Entry type [info] | MATRIX |
| Date [info] |
01-AUG-2004 CREATED;
01-AUG-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00169 |
Name and characterization of the entry
| Description [info] | Multiheme cytochrome c family profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=15; TOPOLOGY=CIRCULAR; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=15; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8475713; R2=0.0151062; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=375; N_SCORE=7.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=275; N_SCORE=6.0; MODE=1; TEXT='RR'; /DEFAULT: M0=-9; D=-20; I=-20; B0=-200; B1=-200; E0=-200; E1=-200; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B0=0; B1=0; E0=0; E1=0; BI=-105; BD=-105; IE=-105; DE=-105; /M: SY='N'; M= -3, -2, -70, -4, -1, -19, -18, -10, -15, -2, -14, -9, 1, -11, -2, -4, -1, -4, -12, -24, -13, -2; /I: I0=0; I=-1; /M: SY='N'; M= -8, 0, -70, -1, -2, -16, -12, -80, -16, -1, -15, -10, 0, -7, -2, -1, -1, 0, -14, -23, -10, -3; /M: SY='E'; M= -4, 2, -90, 3, 5, -24, -5, -30, -20, -3, -20, -13, 2, -3, 2, -4, 2, -5, -18, -28, -17, 2; /M: SY='A'; M= 1, -8, -70, -8, -1, -19, -17, -30, -8, 1, -9, -5, -5, -10, -3, -3, -4, -4, -3, -25, -13, -3; /M: SY='S'; M= -2, 1, -70, -2, -4, -5, -3, -30, -17, -8, -16, -12, 3, -15, -6, 0, 6, 6, -12, -24, -12, -5; /M: SY='C'; M= *, *, 120, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *; /M: SY='A'; M= 6, -14, -80, -19, -14, -10, -14, -55, 1, -11, -3, -1, -11, -48, -10, -9, -1, 1, 5, -19, -7, -13; /M: SY='S'; M= 2, 8, -80, 7, 1, -21, 0, -58, -20, -6, -20, -15, 7, -42, -1, -9, 11, 7, -15, -29, -14, 0; /M: SY='C'; M= *, *, 120, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *, *; /M: SY='H'; M= *, *, *, *, *, *, *, 120, *, *, *, *, *, *, *, *, *, *, *, *, *, *; /M: SY='N'; M= -1, -1, -70, -4, -4, -18, -25, -10, -13, -3, -14, -7, 3, -16, -10, -4, 3, 0, -4, -28, -14, -3; /M: SY='E'; M= -5, -1, -70, 0, 2, -19, -9, -30, -16, -4, -16, -10, -2, -1, -2, -7, -2, -6, -15, -25, -14, -1; /M: SY='E'; M= -6, -2, -70, -2, 3, -19, -25, -30, -15, -1, -15, -9, -2, -5, 2, -4, -3, -5, -15, -23, -8, 1; /M: SY='P'; M= -3, 1, -70, 2, 1, -17, -8, -30, -20, -5, -20, -15, 0, 3, -6, -9, 2, -2, -16, -26, -15, -3; /I: I0=0; I=-1; /M: SY='E'; M= -1, 0,-110, 1, 6, -20, -10, -30, -19, -1, -18, -11, -1, -4, 4, -5, 0, -5, -17, -24, -12, 4;» more |
Numerical results [info]
| Total number of hits | 167 in 159 different sequences |
| Number of true positive hits | 167 in 159 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 5 |
| Number of 'partial' sequences | 3 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 97.09 % |
Comments [info]
| Taxonomic range [info] | Archaea, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 3 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | N_Hulo |
| Version [info] | 2 |
Cross-references [info]