PROSITE entry PS51233
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PURL: https://purl.expasy.org/prosite/signature/PS51233
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General information about the entry
| Entry name [info] | VWFD |
| Accession [info] | PS51233 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2006 CREATED;
29-SEP-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51233 |
| Associated ProRule [info] | PRU00580 |
Name and characterization of the entry
| Description [info] | VWFD domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=176; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=171; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3314614; R2=0.0092979; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=933; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=449; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-24; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='C'; M= 41, 50, -51, -26, -77, 45, -32, -52, -61, -53, -67, -29, 16, -26, 3, 24, -15, -27, -81, -73; /M: SY='T'; M= -19, -72, -61, 24, -33, -72, -27, -4, -36, -22, -57, -40, -19, -14, 23, 16, 56, 21, -5, 10; /M: SY='C'; M= 3, 146, -80, -80, -73, -33, -81, -56, -76, -69, -69, -67, -89, -82, -69, -62, -61, -50, -98, -81; /M: SY='S'; M= -7, -29, -63, -17, -53, -35, -13, -23, -5, -14, -6, -29, -68, 1, -8, 57, 38, 9, 30, -10; /M: SY='V'; M= 19, -69, -77, -73, -25, -10, -75, 30, -72, 21, 27, -70, -74, -70, -74, -39, 26, 53, -79, -61; /M: SY='W'; M= -37, -77, 18, -4, 44, -34, -64, -44, -39, -16, -60, -10, -39, -10, -67, 23, -10, -8, 102, 43; /M: SY='G'; M= -35, -77, -22, 1, -80, 83, -65, -83, -13, -81, -72, -7, -36, 6, -53, 5, -34, -44, -76, -23; /M: SY='D'; M= -23, -76, 76, 3, -80, 25, -30, -78, -15, -51, -33, 21, -44, 18, -43, 6, 14, -74, -86, -36; /M: SY='P'; M= -15, -77, -12, -26, 2, 18, -12, -48, 2, -34, -65, -57, 67, 13, 3, 30, 1, -69, -75, -18; /I: I=-38; MD=-97; /M: SY='H'; M= -48, -90, -67, -36, -8, -82, 125, -88, -48, -77, -66, -37, -82, -40, -33, -31, -76, -36,-101, -19; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='Y'; M= -25, -76, -80, -78, 57, -82, -59, 45, -73, -3, -45, -76, -52, -72, -72, -70, -63, 13, -47, 90; /M: SY='T'; M= -38, -50, -47, -31, -5, -74, 25, 13, 11, -4, -30, 9, -72, -6, 24, -10, 40, 28, -77, -4; /M: SY='T'; M= -39, -62, -58, -61, -69, -67, -68, -61, -58, -65, -62, -48, -60, -62, -66, 16, 110, -53, -89, -67; /M: SY='F'; M= -59, -72, -88, -84, 117, -84, -68, -49, -79, -8, -50, -78, -87, -88, -77, -75, -68, -54, -7, -3; /M: SY='D'; M= -67, -80, 112, -25, -86, -64, -53, -85, -55, -85, -82, 29, -68, -54, -64, -19, -57, -83,-101, -40; /M: SY='G'; M= -41, -77, -7, -17, -83, 87, -25, -88, -39, -85, -75, 44, -69, -39, -19, -42, -64, -83, -79, -76; /M: SY='R'; M= 6, -74, -7, -37, -11, -71, 17, -31, 22, 6, -13, -22, -72, 14, 52, -11, 13, 5, -77, -35; /M: SY='H'; M= -29, -74, -22, -21, -1, -70, 42, -23, 23, -13, -8, 7, -17, -10, 19, 25, 9, 9, -73, 26; /M: SY='Y'; M= -44, -78, -76, -76, 77, -58, 19, -45, -70, -14, -50, -73, -84, -69, -49, -69, -67, -37, -38, 105; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='T'; M= -1, -72, 36, -37, -25, -31, 34, -71, -20, -39, -65, 35, 10, -36, 22, 28, 39, -46, -83, -18; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='F'; M= -44, -34, -81, -79, 99, -81, -35, -31, -75, 7, 15, -23, -83, -78, -73, -70, -17, -17, -47, 50; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='P'; M= -46, -80, 4, -19, -19, -61, 31, -36, -26, -18, 15, 22, 75, 47, -10, -7, -3, -51, -79, -44; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='G'; M= -26, -76, -14, -7, -55, 85, -42, -84, -19, -59, -43, -29, -68, -61, -70, 22, -23, -78, -77, -74; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='N'; M= -17, -72, 18, 20, -71, -48, -20, -41, 7, -7, -4, 39, 1, -33, 0, 26, 38, -28, -83, -51; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='C'; M= -24, 141, -78, -52, -56, 16, -41, -77, -75, -62, -10, -65, -86, -79, -81, -43, -62, -48, -95, -79; /M: SY='W'; M= -27, -74, -6, 19, -30, -67, 8, -46, -1, -69, -63, 8, -16, 30, -32, 28, 47, -42, 57, 46; /M: SY='Y'; M= -69, -80, -48, -53, 28, -76, 57, -57, -65, -39, -52, -29, -81, -22, -63, -20, -42, -13, -40, 114; /M: SY='V'; M= -22, -69, -78, -52, -32, -80, -33, 37, -72, 19, 13, -30, -76, -72, -75, -31, 18, 69, -81, -42; /M: SY='L'; M= -22, -70, -85, -78, 31, -84, -70, -11, -78, 78, 14, -82, -83, -73, -76, -75, -63, 0, -69, -50; /M: SY='A'; M= 56, 10, -74, -68, -27, -65, -26, -12, -68, -5, 37, -66, -72, -65, -71, 4, 7, 45, -78, -24; /M: SY='Q'; M= -12, -78, -56, 9, -78, -12, 2, -75, 49, -59, -20, -52, -67, 79, 32, -16, 11, -72, -75, -27; /I: I=-15; MD=-37; /M: SY='D'; M= -29, -80, 70, -5, -79, -26, 6, -23, -52, -58, -72, 1, 5, -21, -37, 3, 29, -17, -92, -20; D=-15; /I: I=-15; MD=-37; /M: SY='C'; M= -66, 112, -22, -54, -36, -51, 2, -20, -81, -67, -74, -77, -37, -9, -37, -61, -74, -12, -92, 24; D=-15; /I: I=-15; MD=-37; /M: SY='C'; M= -63, 51, -27, -57,-101, -18, 34, -70, -70, -82, -34, -40, 15, -14, -29, -8, -60, -75, 2, -92; D=-15; /I: I=-15; MI=0; MD=-37; IM=0; DM=-37; /M: SY='S'; M= -15, -80, 34, 12, -83, -38, -24, -54, -29, -46, -5, 3, 17, -31, -27, 46, 16, -74, -92, -76; D=-15; /I: I=-15; DM=-37; /M: SY='S'; M= -4, -75, 3, 7, -35, 0, -1, -47, -7, -53, 0, 13, 16, 6, -14, 36, 12, -13, -83, -36; D=-15; /I: I=-15; DM=-37; /M: SY='D'; M= -37, -79, 40, 28, -12, -13, 11, -29, -3, -5, -34, 21, 7, -5, -21, -5, -35, -30, 12, 20; D=-15; /I: I=-15; DM=-37; /M: SY='P'; M= -44, -79, 18, 23, -61, 36, 34, -49, -13, -43, -36, 5, 56, 7, -13, 12, -24, -52, -82, -69; /M: SY='D'; M= -21, -73, 43, -9, 4, -47, -15, -72, 14, -63, -40, 19, 9, -1, 11, 27, 43, -68, -13, -19; /M: SY='F'; M= -73, -35, -86, -62, 102, -67, -21, -16, -76, 19, -48, -78, -85, -80, -42, -74, -68, -29, 56, 28; /M: SY='S'; M= 7, -71, -13, 10, -47, -44, -32, -6, -17, -11, 32, 16, -42, -4, 27, 37, 17, -15, -25, -64; /M: SY='V'; M= -38, -71, -53, -77, -33, -85, -81, 58, -75, -3, -7, -77, -78, -26, -77, -55, -55, 78, -80, -25; /M: SY='H'; M= -61, -74, -31, 6, -57, -76, 41, 23, -40, 33, 7, -63, -30, 33, -45, 10, 15, 9, -12, 6; /M: SY='V'; M= 28, -70, -75, -72, -44, 12, -73, 33, -43, 19, 22, -68, -21, -49, -73, -15, -1, 36, -18, -23; /M: SY='R'; M= -40, -79, 14, 43, -79, -31, 27, -68, 43, -57, -66, -1, -66, 28, 54, -20, 3, -74, -81, -65; /M: SY='N'; M= -38, -34, -25, -56, -15, -57, 15, -29, 26, -5, 2, 78, -12, 22, 15, -24, 6, -50, -82, -63; /I: I=-22; MD=-55; /M: SY='E'; M= -2, -26, 23, 27, -81, -15, -19, -41, -3, -61, -41, -47, -47, 3, -16, -2, -68, 6, 4, -12; D=-22; /I: I=-22; MD=-55; /M: SY='P'; M= -15, -91, -7, -37, -51, -31, 40, -9, 14, -81, -33, -2, 43, 25, -30, -30, -71, -40, -91, -31; D=-22; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='C'; M= -59, 103, -94, -59, -85, -96, -62, -46, -59, -30, -80, -41,-102, -57, -12, -37, -14, -15, -17, -32; D=-22; /I: I=-22; DM=-55; /M: SY='G'; M= -33, -10, 9, -36, -48, 52, -12, -88, -49, -41, -10, -11, -19, -19, -4, 0, -52, -85, -25, -32; D=-22; /I: I=-22; DM=-55; /M: SY='S'; M= 8, -82, -10, -40, -62, 14, 0, -73, -40, -8, -41, -37, 3, 14, -14, 18, -1, -30, -10, 0; D=-22; /I: I=-22; DM=-55; /M: SY='S'; M= 3, -16, 18, -14, -74, 2, -17, -28, 8, -31, -36, 29, 21, 29, -15, 29, 14, -29, -31, -44; /M: SY='N'; M= -3, -31, 34, 21, -77, 20, 14, -73, -1, -25, -66, 38, 9, 15, -7, 14, -9, -41, -83, -68; /M: SY='G'; M= 8, -73, 0, 16, -68, 30, -28, -30, 17, -23, 6, 6, -30, -41, -7, 6, 9, 5, -4, -10; /I: I=-19; MD=-47; /M: SY='N'; M= 3, -84, -15, -12, -35, -10, -49, -36, -6, -16, -33, 9, -1, -4, -30, -4, -24, 6, -87, -10; D=-19; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='T'; M= -4, -45, -46, -25, -16, -38, -73, -26, -27, -48, -22, 2, -28, -66, -52, 45, 51, -1, -89, -72; D=-19; /I: I=-19; DM=-47; /M: SY='C'; M= -43, 109, -40, -4, -13, -12, -44, -58, -56, -58, -71, 2, -85, -19, -41, -11, -28, -17, 44, 12; D=-19; /I: I=-19; DM=-47; /M: SY='L'; M= -43, -17, -69, -22, -8, -31, -34, 10, -50, 34, 1, -30, 5, 4, 10, 24, 14, 8, -18, -33; /M: SY='K'; M= -17, -15, -47, -3, -73, -39, 15, -23, 58, -49, -1, -5, -55, 29, 46, -12, -1, -32, 16, -40; /M: SY='S'; M= 28, -72, -21, 17, -26, -11, 0, -30, 8, -37, -38, -5, -47, 17, 11, 43, -2, -31, -79, -45; /M: SY='V'; M= -34, -48, -38, -78, 3, -85, -81, 61, -77, 20, -40, -77, -79, -76, -79, -53, -40, 67, -78, -57; /M: SY='T'; M= 6, -71, -40, 9, -50, -68, 1, 12, 15, -14, -21, 18, -55, -34, -12, 16, 42, -8, -75, 21; /M: SY='V'; M= -12, -71, -83, -77, -38, -63, -78, 54, -51, 23, 25, -76, -78, -48, -63, -54, -31, 64, -78, -31; /M: SY='Q'; M= -35, -25, -26, 20, 13, -62, -21, 6, 22, 6, -5, -19, -71, 29, 10, -2, 20, -27, 3, 6; /M: SY='L'; M= -25, -74, -30, -10, 10, -64, 24, 32, -50, 33, 8, -70, -40, -26, 1, -46, -14, 28, -13, 12; /M: SY='G'; M= -10, -77, 26, 21, -11, 41, -18, -76, -6, -48, -68, 21, 1, 25, -8, 4, -47, -50, -74, 11; /M: SY='D'; M= -10, -75, 47, 21, -80, 41, -27, -50, -7, -78, -28, 36, 3, -26, -32, 15, -2, -60, -84, -72; /M: SY='Q'; M= -9, -73, 21, -4, -12, -9, 31, -18, -10, -18, -25, -13, -34, 37, -60, 30, 26, -18, -76, 12; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='E'; M= -80, -95, 4, 16, -28, -61, -49, -6, -6, -42, -77, -10, -51, 9, -18, -31, -6, -8, -26, -41; D=-18; /I: I=-18; DM=-45; /M: SY='I'; M= -20, -79, -17, -43, -39, -84, -14, 31, 2, 17, 22, -73, -43, -15, -41, -19, -8, 29, -85, -43; D=-18; /I: I=-18; DM=-45; /M: SY='V'; M= -32, -74, -4, 8, -4, -65, -1, 41, -2, -13, -50, -28, -21, -33, 3, -31, 2, 44, -75, 11; /M: SY='V'; M= -34, -73, -29, -2, -7, -35, 22, 21, 2, 16, 12, -34, -6, 16, -18, -18, 15, 30, -77, -36; /M: SY='L'; M= -42, -73, -3, -10, 9, -44, -64, 11, 0, 31, 8, -6, -30, 9, 5, -15, 19, 6, -11, -11; /M: SY='H'; M= 3, -12, 12, -24, -14, -26, 23, -12, 17, 4, 4, 2, -25, 23, 10, 2, -1, 1, -78, -39; /M: SY='S'; M= -9, -14, 14, -2, -12, 13, -14, -52, 10, -34, -44, 21, 3, 2, 2, 29, -4, -24, -19, 5; /M: SY='D'; M= 1, -46, 45, -2, -62, 33, 4, -59, 1, -52, -36, 38, -8, 2, 5, -2, -23, -34, -83, -47; /M: SY='G'; M= -36, -53, 7, -8, -26, 36, 31, -21, 4, -10, 9, 4, -26, -5, 23, -29, -24, 2, 9, -22; /M: SY='E'; M= -20, -31, -18, 36, -60, -8, -9, -44, 32, -35, -31, 4, -27, 30, 2, 7, 29, -11, -80, -35; /M: SY='V'; M= -14, -33, -82, -58, -24, -52, -80, 27, -74, 11, -1, -77, -46, -38, -56, -67, -38, 80, -81, -27; /M: SY='T'; M= -22, -72, -50, -7, -26, -67, -33, -8, 28, 26, 9, -39, -40, -16, 1, -6, 40, 11, -12, -4; /M: SY='V'; M= -35, -71, -46, -23, -5, -38, -31, 18, -33, 7, 4, -31, -35, -1, -55, -51, -26, 72, -26, -34; /M: SY='N'; M= -47, -73, 58, -16, -48, -10, -51, -79, 0, -72, -73, 92, -55, -52, -22, 3, -17, -78, -92, -71; /I: I=-29; MD=-75; /M: SY='G'; M= -49, -38, 20, -22, -80, 72, -65, -78, -31, -57, -72, 18, -16, 0, -15, 3, -15, -21, -81, -58; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='Q'; M= -27, -78, 10, 33, -33, -33, -15, -8, -7, -22, -12, 2, 15, 63, 3, -12, -18, -8, -48, -14; /M: SY='R'; M= -31, -75, 9, 6, -14, -20, -25, -8, 2, -8, -5, -6, 14, 4, 24, 7, -1, 20, -77, -10; /M: SY='V'; M= -25, -72, -21, 0, -7, -50, -11, 19, -2, 5, 11, -49, -47, -32, -58, -30, -8, 63, -32, -35; /M: SY='S'; M= 6, -74, 4, 22, -34, -35, 18, -45, 16, -31, -63, 18, 4, 24, -20, 26, 11, -20, 9, -13; /M: SY='L'; M= -55, -28, -78, -41, 9, -25, -69, 28, -41, 56, -7, -35, -13, -11, -56, -54, -21, 20, -70, 7; /I: I=-19; MD=-49; /M: SY='P'; M= -67, -91, -24, -10, -86, -53, -44, -79, -26, -86, -74, -32, 109, -9, -44, -1, -33, -81, -83, -35; D=-19; /I: I=-19; MD=-49; /M: SY='Y'; M= -17, -43, -7, -21, 43, -50, 27, -41, -27, -24, -39, -46, -24, 8, -24, -36, -33, 4, 6, 66; D=-19; /I: I=-19; MD=-49; /M: SY='W'; M= -28, -79, -28, -39, 6, -75, -10, -3, 10, -25, -45, -7, -53, 10, -39, 31, 19, 4, 32, 8; D=-19; /I: I=-19; MD=-49; /M: SY='S'; M= -22, -81, -9, 0, -79, -20, 18, -47, 9, -18, -44, -6, 13, -13, -5, 34, 9, -43, -88, -32; D=-19; /I: I=-19; MD=-49; /M: SY='G'; M= 9, -43, -12, -15, -53, 17, 11, -44, -7, -47, -72, 5, 9, 17, -47, 5, -19, -54, -23, 10; D=-19; /I: I=-19; MD=-49; /M: SY='N'; M= -52, -95, 7, -6, -36, -26, -36, -27, -38, -43, -45, 24, -51, 4, -58, -2, -4, -51, -20, -51; D=-19; /I: I=-19; MI=0; MD=-49; IM=0; DM=-49; /M: SY='G'; M= -15, -76, -20, 4, -19, 49, 26, -6, -5, -20, 1, -1, -25, 9, -7, -3, -9, -38, -76, -10; /M: SY='Y'; M= -43, -73, -77, -57, 30, -81, -41, 32, -69, 32, -1, -48, -78, -5, -24, -24, 16, 32, -65, 40; /M: SY='H'; M= -50, -76, -27, 12, -24, -44, 43, 16, 7, 1, -55, 14, -40, 25, 11, 25, -16, -8, -21, -3; /M: SY='I'; M= -22, -73, -81, -57, 14, -83, -28, 69, -74, 17, -10, -74, -77, -19, -58, -32, -19, 43, -73, -17; /M: SY='W'; M= -38, -78, 1, 32, -31, -49, 40, -41, 4, -35, -5, 4, -40, 13, 28, 6, 7, -29, 52, 33; /M: SY='Q'; M= -16, -78, 6, -17, -71, -40, -11, -19, 22, -2, -38, -25, 24, 54, 31, -5, 3, -41, 33, -32; /M: SY='S'; M= 1, -25, 0, -2, -33, -33, -38, -34, -14, -8, -17, 18, -42, 12, -2, 52, 13, -13, -36, -5; /M: SY='G'; M= 0, -42, 17, -10, -56, 75, -66, -57, -23, -80, -35, -11, -34, -41, -41, 18, -28, -66, -78, -48; /M: SY='S'; M= -10, -74, 19, 7, 2, -2, -10, 1, -29, -22, -10, 23, -56, 15, 5, 30, -12, -8, -76, -2; /M: SY='Y'; M= -43, -76, -20, -40, 30, 1, 50, -37, -29, -18, 12, 6, -75, -24, 0, 8, 7, -24, 21, 66; /M: SY='V'; M= -35, -71, -59, -51, 6, -81, -49, 42, -57, 28, 11, -46, -77, -70, -73, -18, 21, 45, -71, 29; /M: SY='V'; M= -11, -72, -71, -26, -28, -39, -20, 30, 0, 7, 21, -65, -73, 18, -20, 15, -3, 43, -77, -16; /M: SY='V'; M= -16, -71, -80, -55, -6, -64, -30, 24, -72, 46, 3, -44, -80, -41, -15, -69, -33, 59, -78, -57; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='E'; M= -18, -37, 18, 29, -8, -52, 7, -17, 0, -33, -62, 1, -38, -2, 12, 25, 21, -11, -75, 21; /M: SY='T'; M= 10, -28, -65, -18, 17, -30, -9, 9, -63, -10, -31, -46, -69, -28, -68, 45, 59, -43, 3, -3; /M: SY='P'; M= -42, -80, 34, -1, -80, 14, -13, -66, 27, -59, -54, 5, 64, -12, 17, -8, 4, -66, -29, -47; /I: I=-9; MD=-23; /M: SY='F'; M= 16, -76, -35, 1, 41, -2, -34, 2, -25, 7, -58, -23, -29, -3, -21, 9, -29, -37, -70, 2; D=-9; /I: I=-9; MI=0; MD=-23; IM=0; DM=-23; /M: SY='G'; M= -10, -79, 4, 12, -32, 65, 23, -17, -41, -22, -31, -9, -73, -22, -26, -58, -66, -15, -80, -40; D=-9; /I: I=-9; DM=-23; /M: SY='L'; M= -44, -37, -16, -15, 8, -28, -49, 30, -9, 51, 16, -70, -77, -54, -24, -21, -18, 11, -22, -56; /M: SY='Q'; M= -24, -72, -34, -13, -27, -73, -24, 15, -24, -2, -52, -48, -71, 52, -4, 13, 31, 40, -78, -20; /M: SY='V'; M= -39, -28, -38, -24, -17, -63, -76, 35, -38, 26, -18, -35, -52, -70, -55, -15, 4, 63, -81, -60; /M: SY='Q'; M= -7, -5, -8, -34, -3, -58, -64, -6, 9, 9, 31, -63, -74, 32, 28, -2, -13, 20, 28, -17; /M: SY='W'; M= -19, -80, -41, -24, 39, -34, -67, -12, -47, -1, -25, -23, -46, -8, -51, -41, -13, -19, 121, 57; /M: SY='D'; M= -36, -76, 74, -8, 4, -17, -25, -37, -36, -20, -24, 35, -27, -43, -28, 14, -21, -28, -9, 7; /M: SY='G'; M= -31, -80, 44, -21, -53, 53, 23, -83, 0, -70, -72, 8, 22, -1, 10, -13, -63, -80, 49, -34; /M: SY='G'; M= -44, -76, 15, -11, -4, 29, -2, -6, 13, -8, -60, 24, -72, 0, 16, 10, -22, -15, -76, -3; /M: SY='M'; M= -38, -48, 1, 8, -23, 9, 25, -49, 1, -3, 44, 14, -26, -13, -27, 16, 33, -31, -23, -14; /M: SY='Q'; M= -4, -73, -43, -22, 19, -14, 23, -34, -11, -19, -59, -3, -71, 37, 26, 27, 25, -6, -74, -12; /M: SY='V'; M= 17, -4, -80, -73, 2, -62, -76, 34, -25, 35, -44, -74, -52, -44, -35, -24, -58, 48, 24, -38; /M: SY='Y'; M= -19, -74, -35, -5, 14, -72, 5, -9, 3, -2, 30, -61, -61, 18, 7, 27, 1, 2, -66, 45; /M: SY='V'; M= -45, -73, -27, -57, 0, -84, -77, 58, -57, 21, -16, -48, -78, -38, -22, -41, -38, 60, -77, -38; /M: SY='T'; M= -25, -73, -47, 14, -26, -41, 11, -5, 24, -4, -2, -20, -68, 31, 10, 21, 35, -17, -23, -35; /M: SY='L'; M= 4, -71, -79, -47, -33, -79, -3, 20, -73, 48, 11, -53, 22, -70, -75, -47, -30, 47, -79, -60; /M: SY='P'; M= -10, -76, 39, -23, -9, -3, -21, -72, -39, -60, -69, -18, 65, -39, -42, 49, -3, -35, -79, -4; /M: SY='P'; M= -12, -77, 20, 2, -50, 7, 20, -57, -15, -63, -68, 0, 56, 8, -8, 34, 7, -55, 6, -16; /M: SY='W'; M= 6, -75, -1, 13, -7, -38, 14, -69, 25, -24, -10, -7, -24, 15, 13, 22, 12, -37, 60, -59; /M: SY='Y'; M= -58, -78, -37, -71, 54, -58, 32, -56, -66, -9, 34, -43, -80, -16, -19, -25, -11, -39, 53, 93; /M: SY='Q'; M= 2, -77, -47, -47, 28, -38, 5, -37, 30, -22, 12, -32, -45, 51, 45, -18, -26, -48, 12, 18; /I: I=-33; MD=-84; /M: SY='N'; M= -34, -76, -6, -13, -80, 65, -30, -84, -39, -85, -74, 78, -72, -34, -16, -40, -19, -81, -84, -31; D=-33; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='Q'; M= -22, -12, -25, -36, -76, -42, 27, -76, 53, -31, -64, 10, -55, 63, 31, 2, -24, -74, -10, -11; D=-33; /I: I=-33; DM=-84; /M: SY='T'; M= -56, -66, -69, -68, -37, -52, -72, -16, -66, 13, 2, -60, -69, -30, -71, -36, 87, 44, -85, -63; /M: SY='C'; M= -25, 117, -46, 1, -69, -44, 11, -71, -10, -29, -38, -62, -53, 10, 30, -27, -40, -21, -85, -2; /M: SY='G'; M= -50, -78, -66, -78, -84, 102, -72, -92, -71, -88, -77, -52, -70, -69, -79, -51, -70, -86, -75, -79; /M: SY='L'; M= -52, -71, -85, -76, -34, -86, -70, 5, -77, 84, -9, -83, -84, -12, -75, -77, -64, -21, -73, -55; /M: SY='C'; M= -63, 147, -83, -82, -33, -79, -81, -72, -79, -4, -64, -70, -93, -85, -84, -67, -63, -64, -97, -78; /M: SY='G'; M= -44, -78, -66, -77, -84, 102, -72, -92, -71, -88, -77, -52, -70, -69, -79, -51, -70, -85, -75, -79; /M: SY='N'; M= -49, -70, 9, -58, -32, -61, 7, -6, -12, -47, -64, 94, -31, -55, -9, -31, 39, -22, -90, -67; /M: SY='Y'; M= -28, 55, -75, -77, 80, -49, -57, -46, -71, -31, -10, 24, -84, -73, -71, -67, -65, -61, 53, 80; /M: SY='N'; M= -51, -73, 79, -33, -82, -58, -50, -80, -53, -84, -76, 95, -71, -53, -61, -11, 0, -79, -99, -72; /M: SY='G'; M= -22, -76, 23, -4, -56, 69, -17, -46, -19, -50, -33, 40, -69, -1, -21, -7, -43, -76, -8, -71; /M: SY='N'; M= -65, -25, 59, 47, -27, -67, -21, -24, -8, -39, -22, 66, -69, -8, -7, -42, -34, -47, -34, -21; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='P'; M= 2, -38, -31, -11, -75, -40, -65, -14, 3, -37, -8, -46, 75, 36, -7, 12, 8, -29, -29, -37; /M: SY='E'; M= 11, -74, 8, 34, -35, -19, -9, -37, 6, -36, -47, 13, -67, 8, 21, 24, 19, -42, -23, -14; /M: SY='D'; M= -66, -77, 94, -28, -84, -61, -23, -82, -32, -83, -77, 72, -70, 9, -60, -33, -6, -80, -98, -53; /M: SY='D'; M= -67, -82, 106, 53, -56, -68, -55, -87, -53, -83, -82, -41, -65, -50, -62, -57, -60, -83, -97, -72; /M: SY='F'; M= -53, 6, -84, -80, 98, -82, -52, -28, -75, 25, 22, -27, -85, -52, -35, -64, -66, -39, -5, 19; /M: SY='M'; M= -32, -10, -70, -34, -42, -77, 8, -8, -22, 22, 52, -24, -74, -9, 42, -50, 38, 19, -78, -10; /M: SY='T'; M= -23, -69, -4, -11, -47, -24, -64, -30, -17, 11, 62, -56, -67, -31, -9, 13, 70, -39, -81, -63; /M: SY='P'; M= -11, -83, -18, -24, -80, -55, 13, -57, -21, -35, -66, -63, 96, 6, 25, 19, -58, -48, -81, -72; /M: SY='N'; M= -20, -74, 53, 13, -78, 3, -36, -39, -12, -77, -9, 60, -68, 17, -23, 36, -44, -60, -86, -30; /M: SY='G'; M= -23, -76, -11, -28, -80, 82, -9, -70, -30, -51, -51, 42, -70, -22, -31, -37, -52, -59, -79, -51; /M: SY='C'; M= -18, 48, -12, -6, -67, -27, -20, -9, 20, -9, 13, -27, -70, 17, 11, 17, 35, -21, -79, -7; /M: SY='V'; M= -30, 2, -59, -4, -11, -68, -27, 16, -53, 35, -17, -73, 18, -9, -72, -34, -11, 50, -76, -5; /I: I=-17; MD=-42; /M: SY='A'; M= 44, -36, -65, 30, -39, -71, -71, 5, -26, -4, -15, -66, -71, -62, -55, -45, 44, 8, -82, -39; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='S'; M= -9, -78, 23, 20, -46, -13, -21, -75, 2, -60, 10, 5, 12, -7, 9, 27, 22, -44, -86, -71; D=-17; /I: I=-17; DM=-42; /M: SY='D'; M= -47, -6, 62, -26, -76, -36, -36, -21, -1, -30, -38, 51, -70, -37, -53, 39, 29, -68, -91, -70; D=-17; /I: I=-17; DM=-42; /M: SY='P'; M= 28, 14, -32, 1, -24, -30, 1, 14, -60, -20, -58, -42, 56, -41, -72, -1, -30, 15, 11, -11; D=-17; /I: I=-17; DM=-42; /M: SY='E'; M= 11, -76, -15, 41, -16, -36, -10, -28, -2, -4, -14, -10, -6, 16, -8, -5, -9, 5, -77, -3; D=-17; /I: I=-17; DM=-42; /M: SY='E'; M= 13, -76, 27, 54, -31, -38, -7, -38, -14, 5, -15, -35, -20, 1, -31, -12, 0, -10, -82, -67; D=-17; /I: I=-17; DM=-42; /M: SY='F'; M= -45, -35, -87, -83, 107, -84, -36, -49, -79, 9, 3, -78, -87, -84, -77, -74, -41, -42, -12, 23; D=-17; /I: I=-17; DM=-42; /M: SY='G'; M= 49, -71, -47, -71, -56, 60, -10, 5, -69, -27, -13, -61, -71, -66, -58, -23, -45, 15, -78, -70; /M: SY='N'; M= 10, -73, 12, 12, -50, -25, 45, -58, -11, -28, -19, 78, -71, 12, 1, -10, -42, -72, -87, -66; /M: SY='S'; M= 2, -27, -23, -4, -36, -37, -10, -71, -9, -33, -14, -35, -66, -40, -61, 86, 12, -65, -82, -66; /M: SY='W'; M= -75, -96, -91, -75, -15, -75, -47, -71, -69, -69, -69, -49, -33, 11, -72, -77, -82, -83, 164, 58; /M: SY='K'; M= 12, -76, -59, 14, -47, -44, -32, -16, 55, -16, -35, -40, -68, 45, 38, -27, -2, -32, -76, -65; /M: SY='V'; M= 4, -71, -24, -4, -54, -78, -72, 23, -36, 38, 30, -71, -50, -66, -71, -38, 5, 47, -38, -20; /I: I=-45; MD=-115; /M: SY='P'; M= -22, -7, 8, 10, -34, -8, -18, -55, 9, -35, -22, 31, 42, 28, -28, 23, 7, -42, -82, -46; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='D'; M= 5, -76, 37, 16, -81, 27, -24, -59, -6, -71, -70, 20, 26, 22, -15, 24, -17, -33, -83, -71; /M: SY='E'; M= -9, 20, 23, 42, -48, -11, -62, -39, -28, -34, -11, -28, 41, 8, -27, 25, 17, -51, -24, -51; /I: I=-23; MD=-58; /M: SY='E'; M= -61, -85, 18, 28, -14, 2, -42, -45, -28, -37, -76, 18, 1, 9, -17, 26, -11, -79, -89, -75; D=-23; /I: I=-23; MI=0; MD=-58; IM=0; DM=-58; /M: SY='C'; M= -46, 145, -50, -54, -73, -75, -50, -77, -74, -50, -69, -43, -88, -34, -80, -1, -38, -54, -99, -80; /M: SY='P'; M= -11, -76, -4, 13, -13, -14, -6, -36, -22, -5, -16, 16, 40, 34, 0, 13, -3, -22, 12, -35; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 185 in 85 different sequences |
| Number of true positive hits | 185 in 85 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 13 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | VWFD |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
85 sequences
APLP_DROME (Q9V496), APLP_GALME (Q68YP1), APLP_LOCMI (Q9U943), APLP_MANSE (Q25490), BMPER_HUMAN (Q8N8U9), BMPER_MOUSE (Q8CJ69), CLOT_PENMO (Q9U572), FCGBP_HUMAN (Q9Y6R7), HMCT_BOMMO (P98092), KCP_HUMAN (Q6ZWJ8), KCP_MOUSE (Q3U492), KCP_XENLA (Q9IBG7), LUCI_VARHI (P17554), MESH_BOMMO (H9JIQ1), MESH_DROME (Q0KHY3), MLP_ACRMI (B3EWY9), MUC19_BOVIN (P98091), MUC19_HUMAN (Q7Z5P9), MUC19_MOUSE (Q6PZE0), MUC2L_RAT (P98089), MUC2_HUMAN (Q02817), MUC2_MOUSE (Q80Z19), MUC2_RAT(Q62635), MUC4_HUMAN (Q99102), MUC4_MOUSE (Q8JZM8), MUC4_RAT(Q63661), MUC5A_HUMAN (P98088), MUC5B_CHICK (Q98UI9), MUC5B_HUMAN (Q9HC84), MUC6_CHICK (F1NBL0), MUC6_HUMAN (Q6W4X9), MUC6_MOUSE (Q80T03), OTOGL_HUMAN (Q3ZCN5), OTOGL_MOUSE (F7A4A7), OTOGL_PONAB (Q5RCW9), OTOG_HUMAN (Q6ZRI0), OTOG_MOUSE (O55225), SSPO_BOVIN (P98167), SSPO_CHICK (Q2PC93), SSPO_HUMAN (A2VEC9), SSPO_MOUSE (Q8CG65), SSPO_RAT(Q700K0), SUSD2_HUMAN (Q9UGT4), SUSD2_MOUSE (Q9DBX3), SUSD_CAEEL (P34501), TECTA_CHICK (Q9YH85), TECTA_HUMAN (O75443), TECTA_MOUSE (O08523), VIT1_AEDAE (Q16927), VIT1_CAEEL (P55155), VIT1_CHICK (P87498), VIT1_FUNHE (Q90508), VIT1_PERAM (Q9U8M0), VIT1_SOLIN (Q7Z1M0), VIT2_CAEEL (P05690), VIT2_CHICK (P02845), VIT2_FUNHE (Q98893), VIT2_PERAM (Q9BPS0), VIT2_SOLIN (Q2VQM6), VIT3_CAEEL (Q9N4J2), VIT3_SOLIN (Q2VQM5), VIT4_CAEEL (P18947), VIT5_CAEEL (P06125), VIT6_CAEEL (P18948), VIT6_OSCTI (Q94637), VITA2_XENLA (P18709), VIT_ACITR (Q90243), VIT_ANTGR (Q05808), VIT_APIME (Q868N5), VIT_BOMMO (Q27309), VIT_ICHUN (Q91062), VIT_ONCMY (Q92093), VIT_PENME (Q6RG02), VIT_TAKPA (A0A292G9J6), VWDE_HUMAN (Q8N2E2), VWDE_MOUSE (Q6DFV8), VWF_BOVIN (P80012), VWF_CANLF (Q28295), VWF_HUMAN (P04275), VWF_MOUSE (Q8CIZ8), VWF_PIG (Q28833), ZAN_HUMAN (Q9Y493), ZAN_MOUSE (O88799), ZAN_PIG (Q28983), ZAN_RABIT (P57999)» more
|
| PDB [Detailed view] |
25 PDB
1LSH; 6N29; 6RBF; 6TM2; 7A5O; 7KWO; 7PMV; 7PNF; 7POV; 7PP6; 7PRL; 7QCL; 7QCN; 7QCU; 7ZWH; 8D3C; 8D3D; 8OES; 8QSP; 8QTB; 8QTV; 8R1U; 8R1Z; 9GVJ; 9GVQ » more |