PROSITE documentation PDOC51742 [for PROSITE entry PS51742]PPC domain profile
Description
The Plants and Prokaryotes Conserved (PPC) domain contains a hydrophobic region in the C terminal, and in the case of plants, is often found in several proteins with the AT-hook motif. Proteins with PPC domains are found in Bacteria, Archaea and the plant kingdom [1,2].
The PPC domain has a single α-helix packed against an antiparallel β-sheet, which is formed by five β-strands (see <PDB:2DT4>) [2]:
Some proteins known to contain a PPC domain are listed below:
- Plant AT-hook motif nuclear localized protein 1 (AHL1), a matrix-attachment region (MAR) binding protein involved in positioning chromatin fibers in the nucleus by an AT-hook motif and PPC.
- Pyrococcus horikoshii putative uncharacterized protein PH0802.
- Cyanobacteria bifunctional protein GlmU.
The profile we developed covers the entire PPC domain.
Last update:December 2014 / First entry.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Fujimoto S. Matsunaga S. Yonemura M. Uchiyama S. Azuma T. Fukui K. |
| Title | Identification of a novel plant MAR DNA binding protein localized on chromosomal surfaces. | |
| Source | Plant Mol. Biol. 56:225-239(2004). | |
| PubMed ID | 15604740 | |
| DOI | 10.1007/s11103-004-3249-5 |
| 2 | Authors | Lin L. Nakano H. Nakamura S. Uchiyama S. Fujimoto S. Matsunaga S. Kobayashi Y. Ohkubo T. Fukui K. |
| Title | Crystal structure of Pyrococcus horikoshii PPC protein at 1.60 A resolution. | |
| Source | Proteins 67:505-507(2007). | |
| PubMed ID | 17295322 | |
| DOI | 10.1002/prot.21270 |
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