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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00031


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00031
General rule information [?]

Accession PRU00031
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS50279; BPTI_KUNITZ_2
Name BPTI/Kunitz inhibitor domain
Function Undefined
Scope(s) Eukaryota
Metazoa
Example(s) Q60495;

Propagated annotation [?]

Keywords [?]

Protease inhibitor
Serine protease inhibitor
case <FTTag:disulf>
Disulfide bond
end case

Gene Ontology [?]

GO:0004866; Molecular function:endopeptidase inhibitor activity
GO:0004867; Molecular function:serine-type endopeptidase inhibitor activity

Cross-references [?]

PROSITE PS00280; BPTI_KUNITZ_1; 1;

Features [?]

From: PS50279
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="BPTI/Kunitz inhibitor #"
DISULFID 1 51 disulf C-x*-C
DISULFID 10 34 disulf C-x*-C
DISULFID 26 47 disulf C-x*-C

Additional information [?]

Size range 51-76 amino acids
Related rules None
Fusion None
Repeats 1-5
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]