We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00070
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00070
General rule information
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| Accession | PRU00070 |
| Dates | 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 12) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50809; DM_2 |
Name | DM DNA-binding domain |
| Function | The DM domain binds DNA as a dimer, allowing the recognition of pseudopalindromic sequences. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | P23023; |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0005634; Cellular component:nucleus |
Cross-references
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| PROSITE | PS40000; DM_1; 1; |
Features
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| From: PS50809 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | from | to | /note="DM #" | |||||||||
Additional information
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| Size range | 47-49 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [49] All [ 49 ]
- Retrieve set of proteins with 3D structure for this domain