ProRule PRU00071
General rule information
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| Accession | PRU00071 |
| Dates | 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 16) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50884; ZF_DOF_2 |
Name | Zinc finger Dof-type |
| Function | Like other zinc fingers the Dof domain has a dual activity: it binds DNA in a sequence-specific manner with the core binding site formed by the AAAG sequence and it can also mediates protein-protein interaction. |
| Scope(s) |
Eukaryota Magnoliopsida |
| Example(s) | Q43385 (DOF37_ARATH); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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| Nucleus | |
| DNA-binding | |
| Zinc-finger | |
| case <Feature:PS50884:3=[CH]> and <Feature:PS50884:6=[CH]> and <Feature:PS50884:28=[CH]> and <Feature:PS50884:31=[CH]> | |
| Zinc | |
| Metal-binding | |
| end case | |
Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0005634; Cellular component:nucleus |
Cross-references
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| PROSITE | PS01361; ZF_DOF_1; 1; |
Features
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| From: PS50884 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS50884:3=[C]> and <Feature:PS50884:6=[C]> and <Feature:PS50884:28=[C]> and <Feature:PS50884:31=[C]> | ||||||||||||
| ZN_FING | from | to | /note="Dof-type #" | |||||||||
| else case <Feature:PS50884:3=[CH]> and <Feature:PS50884:6=[CH]> and <Feature:PS50884:28=[CH]> and <Feature:PS50884:31=[CH]> | ||||||||||||
| ZN_FING | from | to | /note="Dof-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | to | /note="Dof-type #; degenerate" | |||||||||
| end case | ||||||||||||
| BINDING | 3 | 3 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 6 | 6 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 28 | 28 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 31 | 31 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
Additional information
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| Size range | 55-55 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [43] All [ 43 ]
- Retrieve set of proteins with 3D structure for this domain