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ProRule PRU00071


General rule information [?]

Accession PRU00071
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 16)
Data class Domain;
Predictors PROSITE; PS50884; ZF_DOF_2
Name Zinc finger Dof-type
Function Like other zinc fingers the Dof domain has a dual activity: it binds DNA in a sequence-specific manner with the core binding site formed by the AAAG sequence and it can also mediates protein-protein interaction.
Scope(s) Eukaryota
Magnoliopsida
Example(s) Q43385 (DOF37_ARATH);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

Nucleus
DNA-binding
Zinc-finger
case <Feature:PS50884:3=[CH]> and <Feature:PS50884:6=[CH]> and <Feature:PS50884:28=[CH]> and <Feature:PS50884:31=[CH]>
Zinc
Metal-binding
end case

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus

Cross-references [?]

PROSITE PS01361; ZF_DOF_1; 1;

Features [?]

From: PS50884
Key From To Description Tag Condition FTGroup
case <Feature:PS50884:3=[C]> and <Feature:PS50884:6=[C]> and <Feature:PS50884:28=[C]> and <Feature:PS50884:31=[C]>
ZN_FING from to /note="Dof-type #"
else case <Feature:PS50884:3=[CH]> and <Feature:PS50884:6=[CH]> and <Feature:PS50884:28=[CH]> and <Feature:PS50884:31=[CH]>
ZN_FING from to /note="Dof-type #; atypical"
else
ZN_FING from to /note="Dof-type #; degenerate"
end case
BINDING 3 3 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 6 6 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 31 31 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1

Additional information [?]

Size range 55-55 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]