ProRule PRU00073
General rule information
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| Accession | PRU00073 |
| Dates | 12-DEC-2003 (Created)
8-APR-2020 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50139; Z_BINDING |
Name | Z-binding domain |
| Function | The Z-binding domain (ZBD), also referred to as Zalpha or Zbeta is a 78-amino-acid protein fold that specifically binds to Z-DNA as well as to Z- RNA but not to B-DNA. ZBDs might play an important role of in innate antiviral immune responses. |
| Scope(s) |
Eukaryota Eutheria Viruses Orthopoxvirus |
| Example(s) | Q99MU3 (DSRAD_MOUSE); |
Propagated annotation
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Features
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| From: PS50139 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Z-binding #" | |||||||||
Additional information
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| Size range | 66-70 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [6] Viruses [5] All [ 11 ]
- Retrieve set of proteins with 3D structure for this domain