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annotation rule: PRU00073

General rule information [?]

Accession PRU00073
Dates 12-DEC-2003 (Created)
8-APR-2020 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS50139; Z_BINDING
Names Z-binding domain; ZBD; Zalpha; Zbeta
Function The Z-binding domain (ZBD), also referred to as Zalpha or Zbeta is a 78-amino-acid protein fold that specifically binds to Z-DNA as well as to Z- RNA but not to B-DNA. ZBDs might play an important role of in innate antiviral immune responses.

Propagated annotation [?]

Features [?]

From: PS50139
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Z-binding #        

Additional information [?]

Size range 66-70 amino acids
Related rules None
Repeats 1-2
Topology Undefined
Example Q99MU3 (DSRAD_MOUSE)
Eukaryota; Eutheria
Viruses; Orthopoxvirus


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]