ProRule PRU00111
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00111 |
| Accession | PRU00111 |
| Dates | 12-DEC-2003 (Created)
27-JUN-2022 (Last updated, Version 11) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50932; HTH_LACI_2 |
Name | LacI-type HTH domain |
| Function | The lacI-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain present in the lacI/galR family of transcriptional regulators involved in metabolic regulation in prokaryotes. |
| Scope(s) |
Bacteria |
| Example(s) | P44329 (RBSR_HAEIN); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Cross-references
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| PROSITE | PS00356; HTH_LACI_1; 1; |
Features
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| From: PS50932 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH lacI-type #" | |||||||||
| DNA_BIND | 3 | 22 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 54-62 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [183] All [ 183 ]
- Retrieve set of proteins with 3D structure for this domain