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General rule information [?]

Accession PRU00133
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 11)
Data class Domain
Predictors PROSITE; PS50090; MYB_LIKE
Names Myb-like domain; Myb/SANT domain; Myb-like repeat
Function The myb-like domain resembles the myb-type HTH domain, which is a DNA-binding, helix-turn-helix (HTH) domain of ~55 amino acids, typically occurring in a tandem repeat. Myb-like domains can be involved in different functions, such as protein-interactions or DNA-binding. The SANT domain does not bind to DNA, despite its resemblance to myb-like domains, but it is a protein-protein interaction module that can bind to histone-tails (see ).

Propagated annotation [?]

Features [?]

From: PS50090
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     entry     exit       Myb-like #        

Additional information [?]

Size range 40-120 amino acids
Related rules PRU00625; PRU00624
Repeats 1-5
Topology Undefined
Example O14108 (ETA2_SCHPO)
Viruses; Alpharetrovirus


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]