General rule information
[?]
Accession |
PRU00159 |
Dates |
12-DEC-2003 (Created) 14-MAY-2022 (Last updated, Version 46) |
Predictors |
PROSITE; PS50011; PROTEIN_KINASE_DOM
|
Name |
Protein kinase domain |
Propagated annotation
[?]
case <Feature:PS00108>
else case <Feature:PS00109>
else case <FT:4>
end case
case not <FTTag:active>
Domain |
The protein kinase domain is predicted to be catalytically inactive. |
end case
case <Feature:PS00108>
Similarity |
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. |
else case <Feature:PS00109> and <AnyFeature:PS51550>
Similarity |
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. |
else case <Feature:PS00109>
Similarity |
Belongs to the protein kinase superfamily. Tyr protein kinase family. |
end case
case <FT:3>
else case <Feature:PS00107>
end case
case <Feature:PS00108>
PROSITE |
PS00108; PROTEIN_KINASE_ST; 1; |
else case <Feature:PS00109>
end case
case <Feature:PS00108>
GO:0016301; Molecular function: kinase activity.
GO:0016740; Molecular function: transferase activity.
GO:0004674; Molecular function: protein serine/threonine kinase activity.
else case <Feature:PS00109>
GO:0016301; Molecular function: kinase activity.
GO:0016740; Molecular function: transferase activity.
GO:0004713; Molecular function: protein tyrosine kinase activity.
end case
case <FTTag:ATP>
end case
From: PS50011 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
Protein kinase #
|
|
|
|
|
|
|
case <Feature:PS50011:30=K> or <Feature:PS00107>
BINDING
|
|
7
|
|
15
|
|
/ligand="ATP" /ligand_id="30616
|
|
ATP
|
|
|
|
|
end case
case <Feature:PS50011:30=K>
BINDING
|
|
30
|
|
30
|
|
/ligand="ATP" /ligand_id="30616
|
|
|
|
|
|
|
end case
case <FTTag:ATP>
ACT_SITE
|
|
124
|
|
124
|
|
Proton acceptor
|
|
active
|
|
D
|
|
|
end case
Additional information
[?]
Size range |
205-549 amino acids |
Related rules |
None |
Repeats |
1-2 |
Topology |
Undefined |
Example |
O54967 (ACK1_MOUSE) |
Scope |
Eukaryota
Bacteria
Viruses |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]