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annotation rule: PRU00191 |
Accession | PRU00191 |
Dates | 12-DEC-2003 (Created) 20-NOV-2019 (Last updated, Version 7) |
Data class | Domain |
Predictors | PROSITE; PS50001; SH2 |
Name | SH2 domain |
Function | SH2 domains function as regulatory modules of intracellular signalling cascades by interacting with high affinity to phosphotyrosine- containing target peptides in a sequence-specific and strictly phosphorylation-dependent manner. |
From: PS50001 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | SH2 # |
Size range | 65-129 amino acids |
Related rules | None |
Repeats | 1-2 |
Topology | Undefined |
Example | Q13239 (SLAP1_HUMAN) |
Scope | Eukaryota
Viruses; Retroviridae |
Eukaryota | [433] | |
Viruses | [18] | |
All | [ 451 ] |