PRU00191
General rule information
[?]
| Accession | PRU00191 |
| Dates | 12-DEC-2003 (Created) 20-NOV-2019 (Last updated, Version 7) |
| Data class | Domain |
| Predictors | PROSITE; PS50001; SH2 |
| Name | SH2 domain |
| Function | SH2 domains function as regulatory modules of intracellular signalling cascades by interacting with high affinity to phosphotyrosine- containing target peptides in a sequence-specific and strictly phosphorylation-dependent manner. |
Propagated annotation
[?]
Keywords
[?]
Features
[?]
| From: PS50001 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | SH2 # | |||||||||
Additional information
[?]
| Size range | 65-129 amino acids |
| Related rules | None |
| Repeats | 1-2 |
| Topology | Undefined |
| Example | Q13239 (SLAP1_HUMAN) |
| Scope | Eukaryota
Viruses; Retroviridae |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
-
UniProtKB/Swiss-Prot sets
Eukaryota [436] Viruses [18] All [ 454 ]
- Retrieve set of proteins with 3D structure for this domain