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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00237


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00237
General rule information [?]

Accession PRU00237
Dates 12-DEC-2003 (Created)
27-JUN-2022 (Last updated, Version 12)
Data class Domain;
Predictors PROSITE; PS50061; ETS_DOMAIN_3
Name ETS domain
Function Involved in DNA-binding. It seems to recognize purine-rich sequences.
Scope(s) Eukaryota
Viruses
Example(s) P14921;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

DNA-binding
Nucleus
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS00345; ETS_DOMAIN_1; 1;
PROSITE PS00346; ETS_DOMAIN_2; 1;

Features [?]

From: PS50061
Key From To Description Tag Condition FTGroup
DNA_BIND from to /note="ETS #"

Additional information [?]

Size range 80-83 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]