ProRule PRU00245
General rule information
[?]
| Accession | PRU00245 |
| Dates | 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 16) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50807; GCM |
Name | GCM domain |
| Function | The GCM motif has been shown to be a DNA binding domain that recognizes preferentially the nonpalindromic octamer 5'-ATGCGGGT-3'. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9NP62 (GCM1_HUMAN); |
Propagated annotation
[?]
Comments
[?]
| SUBCELLULAR LOCATION | Nucleus. |
Keywords
[?]
| Developmental protein | |
| DNA-binding | |
| Nucleus | |
| Transcription | |
| Transcription regulation | |
| case <FTGroup:1> | |
| Metal-binding | |
| Zinc | |
| end case | |
Gene Ontology
[?]
| GO:0007275; Biological process:multicellular organism development | |
| GO:0003677; Molecular function:DNA binding | |
| GO:0005634; Cellular component:nucleus | |
| GO:0006355; Biological process:regulation of DNA-templated transcription | |
| GO:0006351; Biological process:DNA-templated transcription | |
| case <FTGroup:1> | |
| GO:0046872; Molecular function:metal ion binding | |
| GO:0008270; Molecular function:zinc ion binding | |
| end case | |
Features
[?]
| From: PS50807 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | from | to | /note="GCM #" | |||||||||
Additional information
[?]
| Size range | 156-160 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Eukaryota [7] All [ 7 ]
- Retrieve set of proteins with 3D structure for this domain