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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00279


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00279
General rule information [?]

Accession PRU00279
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 13)
Data class Domain;
Predictors PROSITE; PS50255; CYTOCHROME_B5_2
Name Cytochrome b5 family, heme-binding domain
Function A membrane-bound hemoprotein which acts as an electron carrier for several membrane-bound oxygenases
Scope(s) Eukaryota
Bacteria
Example(s) P00171;

Propagated annotation [?]

Keywords [?]

case <FTGroup:1>
Heme
Iron
Metal-binding
end case

Cross-references [?]

PROSITE PS00191; CYTOCHROME_B5_1; 1;

Features [?]

From: PS50255
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Cytochrome b5 heme-binding #"
BINDING 36 36 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 60 60 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1

Additional information [?]

Size range 76-85 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]