ProRule PRU00280

General rule information [?]

Accession PRU00280
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 12)
Data class Domain;
Predictors PROSITE; PS50846; HMA_2
Name Heavy-metal-associated domain
Function Found in proteins that transport or detoxify heavy metals. This domain contains two conserved cysteines that could be involved in the binding of these metals.
Scope(s) Eukaryota
Example(s) Q47840 (COPZ_ENTHA);

Propagated annotation [?]

Keywords [?]

end case

Cross-references [?]

PROSITE PS01047; HMA_1; 1;

Features [?]

From: PS50846
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HMA #"
BINDING 12 12 /ligand="a metal cation"
C 1
BINDING 15 15 /ligand="a metal cation"
C 1

Additional information [?]

Size range 54-75 amino acids
Related rules None
Fusion None
Repeats 1-6
Topology Undefined


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UniProtKB rule member sequences [?]