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| annotation rule: PRU00280 |
General rule information
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| Accession | PRU00280 |
| Dates | 12-DEC-2003 (Created) 21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
| Predictors | PROSITE; PS50846; HMA_2 |
| Name | Heavy-metal-associated domain |
| Function | Found in proteins that transport or detoxify heavy metals. This domain contains two conserved cysteines that could be involved in the binding of these metals. |
Propagated annotation
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Cross-references
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| PROSITE | PS01047; HMA_1; 1; |
Keywords
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case <FTGroup:1>
end case
Features
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| From: PS50846 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | HMA # | |||||||||
| METAL | 11 | 11 | C | 1 | ||||||||
| METAL | 14 | 14 | C | 1 | ||||||||
Additional information
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| Size range | 54-75 amino acids |
| Related rules | None |
| Repeats | 1-6 |
| Topology | Undefined |
| Example | Q47840 (COPZ_ENTHA) |
| Scope | Eukaryota
Bacteria |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Archaea [2] Bacteria [111] Eukaryota [90] All [ 203 ]
- Retrieve set of proteins with 3D structure for this domain