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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00300


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00300
General rule information [?]

Accession PRU00300
Dates 12-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 14)
Data class Domain;
Predictors Metamotif; -; PS50021~7,91~PS50021
Name Actin-binding region
Function Each single actin-binding region, comprising two CH domains, is able to bind one actin monomer in the filament.
Scope(s) Eukaryota
Example(s) O97592;

Propagated annotation [?]

Keywords [?]


Gene Ontology [?]

GO:0003779; Molecular function:actin binding

Cross-references [?]

PROSITE PS50021; CH; 2;
PROSITE PS00019; ACTININ_1; 1-2;
PROSITE PS00020; ACTININ_2; 1-2;

Features [?]

From: any
Key From To Description Tag Condition FTGroup
REGION from to /note="Actin-binding #"

Additional information [?]

Size range 225-325 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.