ProRule PRU00345
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PURL: https://purl.expasy.org/prosite/rule/PRU00345
General rule information
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| Accession | PRU00345 |
| Dates | 01-JUN-2004 (Created)
27-JUN-2022 (Last updated, Version ) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50995; HTH_MARR_2 |
Name | MarR-type HTH domain |
| Function | The marR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 135 amino acids present in transcription regulators of the marR/slyA family, involved in the development of antibiotic resistance. |
| Scope(s) |
Bacteria Archaea |
| Example(s) | Q93CC3; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Cross-references
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| PROSITE | PS01117; HTH_MARR_1; 1; |
Features
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| From: PS50995 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH marR-type #" | |||||||||
| DNA_BIND | 47 | 70 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 120-160 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Cytoplasmic |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [1] Bacteria [193] All [ 194 ]
- Retrieve set of proteins with 3D structure for this domain