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annotation rule: PRU00345

General rule information [?]

Accession PRU00345
Dates 1-JUN-2004 (Created)
27-JUN-2022 (Last updated, Version 10)
Data class Domain
Predictors PROSITE; PS50995; HTH_MARR_2
Name MarR-type HTH domain
Function The marR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 135 amino acids present in transcription regulators of the marR/slyA family, involved in the development of antibiotic resistance.

Propagated annotation [?]


Cross-references [?]

PROSITE PS01117; HTH_MARR_1; 1;

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.

Keywords [?]


Features [?]

From: PS50995
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       HTH marR-type #        
DNA_BIND     47     70       H-T-H motif        

Additional information [?]

Size range 120-160 amino acids
Related rules None
Repeats 1
Topology Cytoplasmic
Example Q93CC3 (HOSA_ECOLX)
Scope
Bacteria
Archaea

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]