ProRule PRU00362
General rule information
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Accession | PRU00362 |
Dates | 11-OCT-2004 (Created)
19-NOV-2022 (Last updated, Version 20) |
Data class | Domain; |
Predictors |
PROSITE; PS50990; PEPTIDASE_C39 |
Name | Peptidase family C39 domain |
Function | This domain is a thiol peptidase found in ABC transporters, and belongs to the C39 peptidase family. |
Scope(s) |
Bacteria Archaea |
Example(s) | P08716 (HLYBP_ECOLX); |
Propagated annotation
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Identifier, protein and gene names
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case (<Feature:PS50990:7=C> and <Feature:PS50990:81=H>) | |
Protein name | + RecName: EC=3.4.22.-; |
end case |
Keywords
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case <OC:Bacteria> or <OC:Archaea> | |
Transport | |
end case | |
case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2> | |
Membrane | |
Cell inner membrane | |
end case | |
case <OC:Bacteria> or <OC:Archaea> | |
Transmembrane | |
ATP-binding | |
Nucleotide-binding | |
end case | |
case (<Feature:PS50990:7=C> and <Feature:PS50990:81=H>) | |
Thiol protease | |
Hydrolase | |
Protease | |
end case | |
case <Feature:PS50990:7=C> |
Cross-references
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PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
PROSITE | PS50990; PEPTIDASE_C39; 1; |
PROSITE | PS50929; ABC_TM1F; 1; |
Features
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From: PS00017 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | from | to | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" /ligand_label="#" |
|||||||||
From: PS50990 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="Peptidase C39 #" | |||||||||
case <Feature:PS50990:7=C> | ||||||||||||
ACT_SITE | 7 | 7 | ||||||||||
else case <Feature:PS50990:81=H> | ||||||||||||
ACT_SITE | 81 | 81 | ||||||||||
end case |
Additional information
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Size range | 121 amino acids |
Related rules |
PRU01700 |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
Comments | A number of the proteins are classified as non-peptidase homologues as they either have been found experimentally to be without peptidase activity, or to lack amino acid residues that are believed to be essential for the catalytic activity. |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [2] Bacteria [36] Viruses [1] All [ 39 ]
- Retrieve set of proteins with 3D structure for this domain