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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00367


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00367
General rule information [?]

Accession PRU00367
Dates 09-NOV-2004 (Created)
19-NOV-2022 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS51024; ZF_FCS
Name Zinc finger FCS-type
Function This domain can bind RNA in a non-sequence-specific manner.
Scope(s) Eukaryota
Example(s) P39769;

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS51024:10=[CH]> and <Feature:PS51024:13=[CH]> and <Feature:PS51024:30=[CH]> and <Feature:PS51024:34=[CH]>
Zinc
Metal-binding
end case

Features [?]

From: PS51024
Key From To Description Tag Condition FTGroup
case <Feature:PS51024:10=[C]> and <Feature:PS51024:13=[C]> and <Feature:PS51024:30=[C]> and <Feature:PS51024:34=[C]>
ZN_FING from to /note="FCS-type #"
else case <Feature:PS51024:10=[CH]> and <Feature:PS51024:13=[CH]> and <Feature:PS51024:30=[CH]> and <Feature:PS51024:34=[CH]>
ZN_FING from to /note="FCS-type #; atypical"
else
ZN_FING from to /note="FCS-type #; degenerate"
end case
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 13 13 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 30 30 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 34 34 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 30-50 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]