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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00372


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00372
General rule information [?]

Accession PRU00372
Dates 23-NOV-2004 (Created)
27-JUN-2022 (Last updated, Version 15)
Data class Domain;
Predictors PROSITE; PS51029; MADF
Name MADF domain
Function The myb/SANT-like domain in Adf-1 (MADF) is a ~80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple trinucleotide repeats.
Scope(s) Eukaryota
Metazoa
Viruses
Example(s) P05552;

Propagated annotation [?]

Comments [?]

case not <OC:Viruses>
SUBCELLULAR LOCATIONNucleus.
end case

Keywords [?]

DNA-binding
case not <OC:Viruses>
Nucleus
end case
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
case not <OCellular component:Viruses>
GO:0005634; Cellular component:nucleus
end case
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS51029
Key From To Description Tag Condition FTGroup
DNA_BIND from to /note="MADF #"

Additional information [?]

Size range 75-85 amino acids
Related rules None
Fusion None
Repeats 1-3
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]