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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00377


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00377
General rule information [?]

Accession PRU00377
Dates 16-DEC-2004 (Created)
21-NOV-2019 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS51051; DSL
Name DSL domain
Function The DSL domain may mediates oligomerization of DSL proteins to form an active ligand and mediates interaction with the extracellular domain of Lin-12/Notch proteins.
Scope(s) Eukaryota
Example(s) P45442;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Cross-references [?]

PROSITE PS51051; DSL; 1;

Features [?]

From: PS51051
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="DSL #"
DISULFID 3 12 disulf C-x*-C
DISULFID 16 28 disulf C-x*-C
DISULFID 36 45 disulf C-x*-C

Additional information [?]

Size range 45 amino acids
Related rules none
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]