 |
|
| annotation rule: PRU00385 |
General rule information
[?]
| Accession | PRU00385 |
| Dates | 18-JAN-2005 (Created) 21-NOV-2019 (Last updated, Version 11) |
| Data class | Domain |
| Predictors | PROSITE; PS51049; KASH |
| Name | KASH domain |
| Function | The KASH or KLS domain is a highly hydrophobic nuclear envelope localization domain of ~60 amino acids comprising an ~20-amino-acid transmembrane region and a 30-35-residue C-terminal region that lies between the inner and the outer nuclear membranes. |
Propagated annotation
[?]
Computed features
[?]
| General | Transmembrane; -; 1; |
Gene Ontology
[?]
GO:0016021; Cellular component: integral component of membrane.
GO:0016020; Cellular component: membrane.
GO:0016020; Cellular component: membrane.
Keywords
[?]
Features
[?]
| From: PS51049 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 9 | Cytoplasmic | |||||||||
| TRANSMEM | 10 | 30 | Helical; Anchor for type IV membrane protein | |||||||||
| TOPO_DOM | 31 | Cter | Perinuclear space | |||||||||
| DOMAIN | from | to | KASH # | |||||||||
Additional information
[?]
| Size range | 55-65 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
| Example | Q8NF91 (SYNE1_HUMAN) |
| Scope | Eukaryota; Metazoa |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
-
UniProtKB/Swiss-Prot sets
Eukaryota [19]
- Retrieve set of proteins with 3D structure for this domain