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General rule information [?]

Accession PRU00387
Dates 20-JAN-2005 (Created)
27-JUN-2022 (Last updated, Version 9)
Data class Domain
Predictors PROSITE; PS51063; HTH_CRP_2
Name Crp-type HTH domain
Function The crp-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70-75 amino acids present in transcription regulators of the crp-fnr family, involved in the control of virulence factors, enzymes of aromatic ring degradation, nitrogen fixation, photosynthesis, and various types of respiration.

Propagated annotation [?]

Cross-references [?]

PROSITE PS00042; HTH_CRP_1; 1;

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.

Keywords [?]

Features [?]

From: PS51063
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       HTH crp-type #        
DNA_BIND     43     62       H-T-H motif        

Additional information [?]

Size range 40-90 amino acids
Related rules None
Repeats 1
Topology Cytoplasmic
Example P27369 (CYSR_SYNE7)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]