PRU00387

General rule information [?]

Accession	PRU00387
Dates	20-JAN-2005 (Created) 27-JUN-2022 (Last updated, Version 9)

Data class

Domain

Predictors

PROSITE; PS51063; HTH_CRP_2

Name	Crp-type HTH domain

Function

The crp-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70-75 amino acids present in transcription regulators of the crp-fnr family, involved in the control of virulence factors, enzymes of aromatic ring degradation, nitrogen fixation, photosynthesis, and various types of respiration.

Propagated annotation [?]

Cross-references [?]

PROSITE

PS00042; HTH_CRP_1; 1;

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.

Keywords [?]

DNA-binding
Transcription
Transcription regulation

Features [?]

From: PS51063

Key From To Description Tag Condition FTGroup

DOMAIN from to HTH crp-type #

DNA_BIND 43 62 H-T-H motif

Additional information [?]

Size range	40-90 amino acids
Related rules	None
Repeats	1
Topology	Cytoplasmic
Example	P27369 (CYSR_SYNE7)
Scope	Bacteria Plastid

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Archaea [1]

Bacteria [85]

Eukaryota [2]

All [ 88 ]
Retrieve set of proteins with 3D structure for this domain

Archaea	[1]
Bacteria	[85]
Eukaryota	[2]
All	[ 88 ]