annotation rule: PRU00388

General rule information [?]

Accession PRU00388
Dates 21-JAN-2005 (Created)
3-SEP-2015 (Last updated, Version 9)
Data class Domain
Predictors PROSITE; PS50127; UBIQUITIN_CONJUGAT_2
Name Ubiquitin-conjugating enzyme
Function Catalyzes the covalent attachment of ubiquitin to target proteins

Propagated annotation [?]


Comments [?]

case <Feature:PS50127:83=C>
Function Catalyzes the covalent attachment of ubiquitin to other proteins.
Catalytic activity ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Pathway Protein modification; protein ubiquitination.
end case

case <Feature:PS50127:83=C>
Similarity Belongs to the ubiquitin-conjugating enzyme family.

Cross-references [?]

end case

PROSITE PS00183; UBIQUITIN_CONJUGAT_1; 1;

Gene Ontology [?]

case <Feature:PS50127:83=C>
GO:0016874; Molecular function: ligase activity.

Keywords [?]

Ligase
Ubl conjugation pathway
end case


Features [?]

From: PS50127
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     83     83       Glycyl thioester intermediate     C  

Additional information [?]

Size range 100-170 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P52484 (UBC21_CAEEL)
Scope Eukaryota

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.


View rule in raw text format (no links)


UniProtKB rule member sequences [?]