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annotation rule: PRU00388

General rule information [?]

Accession PRU00388
Dates 21-JAN-2005 (Created)
15-APR-2020 (Last updated, Version 14)
Data class Domain
Predictors PROSITE; PS50127; UBC_2
Name Ubiquitin-conjugating (UBC) core domain
Function Catalyzes the covalent attachment of ubiquitin to target proteins.

Propagated annotation [?]


Description [?]

case <FTTag:act_site>
+ RecName: EC= 2.3.2.-;
end case


Comments [?]

Similarity Belongs to the ubiquitin-conjugating enzyme family.

Cross-references [?]

case <FTTag:act_site>
PROSITE PS00183; UBIQUITIN_CONJUGAT_1; 1;

Gene Ontology [?]

GO:0016874; Molecular function: ligase activity.

Keywords [?]

Transferase
Ubl conjugation pathway
end case


Features [?]

From: PS50127
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       UBC core #        
ACT_SITE     85     85       Glycyl thioester intermediate   act_site   C  

Additional information [?]

Size range 100-170 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P52484 (UBC21_CAEEL)
Scope
Eukaryota

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]