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ProRule PRU00388
General rule information
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| Accession | PRU00388 |
| Dates | 21-JAN-2005 (Created)
15-APR-2020 (Last updated, Version 14) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50127; UBC_2 |
Name | Ubiquitin-conjugating (UBC) core domain |
| Function | Catalyzes the covalent attachment of ubiquitin to target proteins. |
| Scope(s) |
Eukaryota |
| Example(s) | P52484 (UBC21_CAEEL); |
Propagated annotation
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Identifier, protein and gene names
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| case <FTTag:act_site> | |
| Protein name | + RecName: EC= 2.3.2.-; |
| end case | |
Comments
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| SIMILARITY | Belongs to the ubiquitin-conjugating enzyme family. |
Keywords
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| Transferase | |
| Ubl conjugation pathway | |
| end case | |
Gene Ontology
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| GO:0016874; Molecular function:ligase activity | |
| end case | |
Cross-references
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| PROSITE | PS00183; UBIQUITIN_CONJUGAT_1; 1; |
Features
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| From: PS50127 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="UBC core #" | |||||||||
| ACT_SITE | 85 | 85 | /note="Glycyl thioester intermediate" | act_site | C | |||||||
Additional information
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| Size range | 100-170 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [360] Viruses [9] All [ 369 ]
- Retrieve set of proteins with 3D structure for this domain