ProRule PRU00393
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PURL: https://purl.expasy.org/prosite/rule/PRU00393
General rule information
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| Accession | PRU00393 |
| Dates | 08-FEB-2005 (Created)
27-JUN-2022 (Last updated, Version 11) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51077; HTH_ICLR |
Name | IclR-type HTH domain |
| Function | The iclR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60 amino acids present in transcription regulators of the iclR family, involved in carbon metabolism in eubacteria and archaea. |
| Scope(s) |
Bacteria Archaea Viruses |
| Example(s) | P37728; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Features
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| From: PS51077 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH iclR-type #" | |||||||||
| DNA_BIND | 23 | 42 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 50-75 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Cytoplasmic |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [2] Bacteria [33] Eukaryota [15] All [ 50 ]
- Retrieve set of proteins with 3D structure for this domain