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ProRule PRU00395


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PURL: https://purl.expasy.org/prosite/rule/PRU00395
General rule information [?]

Accession PRU00395
Dates 10-FEB-2005 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51052; CYCLOTIDE
Name Cyclotides
Function Cyclotides (cyclo peptides) are plant peptides of ~30 amino acids with a head-to-tail cyclic backbone and six cysteine residues involved in three disulfide bonds. They are most likely present as defense molecules.
Scope(s) Eukaryota
Viridiplantae
Example(s) P58433 (CYH1_VIOHE); P56254 (KAB1_OLDAF);

Propagated annotation [?]

Comments [?]

FUNCTIONProbably participates in a plant defense mechanism.
PTMThis is a cyclic peptide.
case <Feature:PS60008> and not <Feature:PS60009>
SIMILARITYBelongs to the cyclotide family. Bracelet subfamily.
else case <Feature:PS60009> and not <Feature:PS60008>
SIMILARITYBelongs to the cyclotide family. Moebius subfamily.
else
SIMILARITYBelongs to the cyclotide family.
end case
CAUTIONThis peptide is cyclic. The start position was chosen by similarity to Oak1 (kalata B1) for which the DNA sequence is known.

Keywords [?]

case <Feature:PS60008> and not <Feature:PS60009>
else case <Feature:PS60009> and not <Feature:PS60008>
Plant defense
case <FTTag:disulf>
Disulfide bond
end case

Cross-references [?]

PROSITE PS60008; CYCLOTIDE_BRACELET; 0-1;
PROSITE PS60009; CYCLOTIDE_MOEBIUS; 0-3;

Features [?]

From: PS51052
Key From To Description Tag Condition FTGroup
PEPTIDE from to /note=""
DISULFID 5 19 disulf C-x*-C
DISULFID 9 21 disulf C-x*-C
DISULFID 14 26 disulf C-x*-C

Additional information [?]

Size range 20-35 amino acids
Related rules None
Fusion None
Repeats 1-3
Topology Not cytoplasmic

Copyright

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UniProtKB rule member sequences [?]