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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00401


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00401
General rule information [?]

Accession PRU00401
Dates 15-FEB-2005 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51073; RPEL
Name RPEL repeat
Function RPEL (RPxxxEL) repeats have been shown to be required for unpolymerized actin binding and proteins containing RPEL repeats are able to modify cell shape and/or are important in the regulation of gene expression by the actin cytoskeleton.
Scope(s) Eukaryota
Example(s) Q8IZQ8;

Propagated annotation [?]

Features [?]

From: PS51073
Key From To Description Tag Condition FTGroup
REPEAT from to /note="RPEL #"

Additional information [?]

Size range 20-30 amino acids
Related rules None
Fusion None
Repeats 1-4
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]