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| annotation rule: PRU00407 |
General rule information
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| Accession | PRU00407 |
| Dates | 2-MAR-2005 (Created) 21-NOV-2019 (Last updated, Version 16) |
| Data class | Domain |
| Predictors | PROSITE; PS51030; NUCLEAR_REC_DBD_2 |
| Name | Nuclear hormone receptors DNA-binding domain |
| Function | Nuclear hormone receptors are ligand-activated transcription factors that regulate gene expression by interacting with specific DNA sequences upstream of their target genes. |
Propagated annotation
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Comments
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| Subcellular location | Nucleus. |
Cross-references
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| PROSITE | PS00031; NUCLEAR_REC_DBD_1; 1; |
Gene Ontology
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GO:0003677; Molecular function: DNA binding.
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:0006351; Biological process: transcription, DNA-templated.
GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:0006351; Biological process: transcription, DNA-templated.
GO:0005634; Cellular component: nucleus.
case <Feature:PS51030:4=[CH]> and <Feature:PS51030:7=[CH]> and <Feature:PS51030:21=[CH]> and <Feature:PS51030:24=[CH]> or <Feature:PS51030:40=[CH]> and <Feature:PS51030:46=[CH]> and <Feature:PS51030:56=[CH]> and <Feature:PS51030:59=[CH]>
GO:0046872; Molecular function: metal ion binding.
GO:0008270; Molecular function: zinc ion binding.
GO:0008270; Molecular function: zinc ion binding.
end case
Keywords
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case <Feature:PS51030:4=[CH]> and <Feature:PS51030:7=[CH]> and <Feature:PS51030:21=[CH]> and <Feature:PS51030:24=[CH]> or <Feature:PS51030:40=[CH]> and <Feature:PS51030:46=[CH]> and <Feature:PS51030:56=[CH]> and <Feature:PS51030:59=[CH]>
end case
Features
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| From: PS51030 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | from | to | Nuclear receptor # | |||||||||
case <Feature:PS51030:4=[C]> and <Feature:PS51030:7=[C]> and <Feature:PS51030:21=[C]> and <Feature:PS51030:24=[C]>
else case <Feature:PS51030:4=[CH]> and <Feature:PS51030:7=[CH]> and <Feature:PS51030:21=[CH]> and <Feature:PS51030:24=[CH]>
else
end case
case <Feature:PS51030:40=[C]> and <Feature:PS51030:46=[C]> and <Feature:PS51030:56=[C]> and <Feature:PS51030:59=[C]>
else case <Feature:PS51030:40=[CH]> and <Feature:PS51030:46=[CH]> and <Feature:PS51030:56=[CH]> and <Feature:PS51030:59=[CH]>
else
end case
Additional information
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| Size range | 30-80 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q9W539 (HR4_DROME) |
| Scope | Eukaryota
Viruses |
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UniProtKB rule member sequences
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