ProRule PRU00432
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PURL: https://purl.expasy.org/prosite/rule/PRU00432
General rule information
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| Accession | PRU00432 |
| Dates | 13-APR-2005 (Created)
19-NOV-2022 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51113; ZF_BTK |
Name | Zinc finger Btk-type |
| Function | The Btk-type zinc finger is a domain of ~37 amino acids present in eukaryotic signalling proteins. |
| Scope(s) |
Eukaryota |
| Example(s) | O95294 (RASL1_HUMAN); |
Propagated annotation
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Keywords
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| Zinc-finger | |
| case <Feature:PS51113:9=[CH]> and <Feature:PS51113:20=[CH]> and <Feature:PS51113:21=[CH]> and <Feature:PS51113:31=[CH]> | |
| Zinc | |
| Metal-binding | |
| end case | |
Features
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| From: PS51113 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51113:9=[H]> and <Feature:PS51113:20=[C]> and <Feature:PS51113:21=[C]> and <Feature:PS51113:31=[C]> | ||||||||||||
| ZN_FING | from | to | /note="Btk-type #" | |||||||||
| else case <Feature:PS51113:9=[CH]> and <Feature:PS51113:20=[CH]> and <Feature:PS51113:21=[CH]> and <Feature:PS51113:31=[CH]> | ||||||||||||
| ZN_FING | from | to | /note="Btk-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | to | /note="Btk-type #; degenerate" | |||||||||
| end case | ||||||||||||
| BINDING | 9 | 9 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 20 | 20 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 21 | 21 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 31 | 31 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
Additional information
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| Size range | 30-45 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [23] All [ 23 ]
- Retrieve set of proteins with 3D structure for this domain